AutismKB 2.0

Annotation Detail for ABR


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Basic Information Top
Gene Symbol:ABR ( FLJ45954,MDB )
Gene Full Name: active BCR-related gene
Band: 17p13.3
Quick LinksEntrez ID:29; OMIM: 600365; Uniprot ID:ABR_HUMAN; ENSEMBL ID: ENSG00000159842; HGNC ID: 81
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body13 / 70761183
blastocyst8 / 62319128
fetus79 / 564012140
neonate5 / 31097160
infant3 / 23620127
juvenile2 / 5555635
adult238 / 1939121122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor15 / 94178159
cervical tumor1 / 3436629
chondrosarcoma13 / 82823156
colorectal tumor14 / 114246122
esophageal tumor2 / 17290115
gastrointestinal tumor19 / 119369159
germ cell tumor21 / 26384579
glioma12 / 106883112
head and neck tumor16 / 136302117
kidney tumor11 / 68959159
leukemia50 / 95842521
liver tumor9 / 9635993
lung tumor10 / 10312796
lymphoma2 / 7175527
non-neoplasia13 / 97250133
normal510 / 3360307151
ovarian tumor3 / 7668239
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer2 / 10268019
retinoblastoma6 / 46356129
skin tumor26 / 124949208
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland3 / 3319790
ascites4 / 4001599
bladder0 / 297570 
blood47 / 123478380
bone7 / 7165597
bone marrow3 / 4880161
brain336 / 1100989305
cervix1 / 4817120
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue23 / 215722106
esophagus3 / 20209148
eye40 / 211054189
heart4 / 8962644
intestine28 / 234472119
kidney19 / 21177789
larynx1 / 2414541
liver12 / 20774357
lung25 / 33697474
lymph2 / 4427045
lymph node29 / 91610316
mammary gland19 / 153271123
mouth10 / 67052149
muscle3 / 10771527
nerve1 / 1576863
ovary4 / 10205139
pancreas18 / 21481283
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta19 / 28082567
prostate6 / 18934531
salivary gland3 / 20155148
skin33 / 210574156
spleen7 / 53952129
stomach16 / 96619165
testis20 / 33044260
thymus6 / 8113173
thyroid3 / 4747363
tonsil2 / 16999117
trachea3 / 5241357
umbilical cord2 / 13680146
uterus19 / 23287881
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214671_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.65
Adipocyte5.9
AdrenalCortex7.25
Adrenalgland5.05
Amygdala51.65
Appendix7.5
AtrioventricularNode6.45
BDCA4+_DentriticCells8.9
Bonemarrow6.55
BronchialEpithelialCells5.9
CD105+_Endothelial6.05
CD14+_Monocytes13.55
CD19+_BCells(neg._sel.)6.65
CD33+_Myeloid22.15
CD34+7.6
CD4+_Tcells7.95
CD56+_NKCells14.4
CD71+_EarlyErythroid5.85
CD8+_Tcells8.55
CardiacMyocytes8.6
Caudatenucleus25.05
Cerebellum6.9
CerebellumPeduncles7.8
CiliaryGanglion5.4
CingulateCortex9.75
Colorectaladenocarcinoma25.45
DorsalRootGanglion6
FetalThyroid5.8
Fetalbrain42.5
Fetalliver5.5
Fetallung4.65
GlobusPallidus18.1
Heart15.35
Hypothalamus12.95
Kidney5.2
Leukemia_chronicMyelogenousK-5625.15
Leukemia_promyelocytic-HL-605.1
Leukemialymphoblastic(MOLT-4)4.75
Liver8.95
Lung9.3
Lymphnode4.95
Lymphoma_burkitts(Daudi)8.05
Lymphoma_burkitts(Raji)9.6
MedullaOblongata29.35
OccipitalLobe36.4
OlfactoryBulb4.8
Ovary4.5
Pancreas5
PancreaticIslet7.15
ParietalLobe21.1
Pituitary8.05
Placenta6.25
Pons16.6
PrefrontalCortex65.35
Prostate7.2
Salivarygland6
SkeletalMuscle8.4
Skin6.15
SmoothMuscle7.3
Spinalcord7.85
SubthalamicNucleus7.7
SuperiorCervicalGanglion7.65
TemporalLobe19.95
Testis5.1
TestisGermCell4.75
TestisIntersitial5.2
TestisLeydigCell6.6
TestisSeminiferousTubule5.2
Thalamus6.25
Thymus4.55
Thyroid7.6
Tongue6.6
Tonsil6
Trachea4.95
TrigeminalGanglion8.6
Uterus5
UterusCorpus7.45
WholeBlood14.25
Wholebrain72
colon9.55
pineal_day28.4
pineal_night30.68
retina91.775
small_intestine7.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15327_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.92 ± 0.36
Basal Forebrain7.24 ± 0.32
Basal Part of Pons7 ± 0.48
Cerebellar Cortex6.66 ± 0.33
Cerebellar Nuclei6.42 ± 0.5
Claustrum8.08 ± 0.4
Epithalamus6.86 ± 0.51
Frontal Lobe7.17 ± 0.5
Globus Pallidus6.91 ± 0.66
Hypothalamus6.98 ± 0.39
Insula7.44 ± 0.32
Limbic Lobe7.62 ± 0.39
Mesencephalon7.11 ± 0.63
Myelencephalon7.23 ± 0.46
Occipital Lobe7.21 ± 0.35
Parietal Lobe7.37 ± 0.59
Pontine Tegmentum7.23 ± 0.45
Striatum7.19 ± 0.62
Subthalamus7.14 ± 0.54
Temporal Lobe7.49 ± 0.39
Thalamus7.1 ± 0.35
White Matter5.96 ± 0.89
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AbrCBCerebellum35.57
100
AbrCTXCerebral cortex100
100
AbrHIPHippocampal region100
100
AbrHPFHippocampal formation100
100
AbrHYHypothalamus100
100
AbrLSXLateral septal complex100
100
AbrMBMidbrain100
100
AbrMYMedulla98.3
100
AbrOLFOlfactory bulb100
100
AbrPPons100
100
AbrPALPallidum100
100
AbrRHPRetrohippocampal region100
100
AbrsAMYStriatum-like amygdalar nuclei100
100
AbrSTRStriatum100
100
AbrSTRdStriatum dorsal region100
100
AbrSTRvStriatum ventral region100
100
AbrTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ABR_HUMAN_225 18 225 242 DSHTSVTMEALLYKPIDR PRIDE
ABR_HUMAN_246 27 246 272 STLVLHDLLKHTPVDHPDYPLLQDALR PRIDE
ABR_HUMAN_666 9 666 674 QCVEEVEKR PRIDE
PAp00078282 10 209 218 STLVLHDLLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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