AutismKB 2.0

Annotation Detail for GRIK5


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GRIK5 ( EAA2,GRIK2,KA2 )
Gene Full Name: glutamate receptor, ionotropic, kainate 5
Band: 19q13.2
Quick LinksEntrez ID:2901; OMIM: 600283; Uniprot ID:GRIK5_HUMAN; ENSEMBL ID: ENSG00000105737; HGNC ID: 4583
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult21 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal39 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain18 / 110098916
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node4 / 9161043
mammary gland2 / 15327113
mouth0 / 670520 
muscle1 / 1077159
nerve2 / 15768126
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214966_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.7
Adipocyte7.6
AdrenalCortex10.15
Adrenalgland6.65
Amygdala33.1
Appendix9.5
AtrioventricularNode9.8
BDCA4+_DentriticCells7.95
Bonemarrow9.95
BronchialEpithelialCells7.65
CD105+_Endothelial10.15
CD14+_Monocytes8.35
CD19+_BCells(neg._sel.)7.45
CD33+_Myeloid10.35
CD34+10.7
CD4+_Tcells8.2
CD56+_NKCells8.35
CD71+_EarlyErythroid7.4
CD8+_Tcells6.35
CardiacMyocytes18.95
Caudatenucleus6.95
Cerebellum6.25
CerebellumPeduncles9.75
CiliaryGanglion8.5
CingulateCortex8.3
Colorectaladenocarcinoma7.45
DorsalRootGanglion7.1
FetalThyroid7.55
Fetalbrain7.8
Fetalliver6.85
Fetallung5.35
GlobusPallidus6.1
Heart10.55
Hypothalamus7.55
Kidney6.55
Leukemia_chronicMyelogenousK-5627
Leukemia_promyelocytic-HL-606.8
Leukemialymphoblastic(MOLT-4)6.15
Liver11.35
Lung8.5
Lymphnode6.4
Lymphoma_burkitts(Daudi)9.65
Lymphoma_burkitts(Raji)12.3
MedullaOblongata7
OccipitalLobe6.7
OlfactoryBulb5.75
Ovary5.7
Pancreas6.15
PancreaticIslet8.3
ParietalLobe8.8
Pituitary8.8
Placenta6.55
Pons7.8
PrefrontalCortex11.3
Prostate9.05
Salivarygland6.25
SkeletalMuscle23.45
Skin6.8
SmoothMuscle8.75
Spinalcord7.2
SubthalamicNucleus7.45
SuperiorCervicalGanglion12
TemporalLobe7.2
Testis6.35
TestisGermCell7.45
TestisIntersitial9.1
TestisLeydigCell7.75
TestisSeminiferousTubule6.8
Thalamus7.95
Thymus4.95
Thyroid9.85
Tongue7.95
Tonsil7.5
Trachea6.1
TrigeminalGanglion8.1
Uterus5.7
UterusCorpus8.2
WholeBlood8.2
Wholebrain6.5
colon7.75
pineal_day25.46
pineal_night49.56
retina24
small_intestine6.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_310_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.39 ± 0.47
Basal Forebrain3.75 ± 0.37
Basal Part of Pons5.1 ± 0.21
Cerebellar Cortex4.28 ± 0.48
Cerebellar Nuclei3.68 ± 0.48
Claustrum4.11 ± 0.89
Epithalamus3.58 ± 0.47
Frontal Lobe4.27 ± 0.56
Globus Pallidus3.14 ± 0.52
Hypothalamus3.83 ± 0.56
Insula4.55 ± 0.26
Limbic Lobe4.59 ± 0.39
Mesencephalon4.07 ± 0.54
Myelencephalon4.29 ± 0.61
Occipital Lobe4.19 ± 0.72
Parietal Lobe4.24 ± 0.57
Pontine Tegmentum4.04 ± 0.52
Striatum4.26 ± 0.49
Subthalamus3.92 ± 0.97
Temporal Lobe4.38 ± 0.51
Thalamus4.29 ± 0.54
White Matter2.99 ± 0.68
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Grik5CBCerebellum71.53
73.38
Grik5CTXCerebral cortex100
100
Grik5HIPHippocampal region100
100
Grik5HPFHippocampal formation100
100
Grik5HYHypothalamus100
100
Grik5LSXLateral septal complex100
100
Grik5MBMidbrain100
99.89
Grik5MYMedulla90.46
82.1
Grik5OLFOlfactory bulb100
100
Grik5PPons90.12
78
Grik5PALPallidum100
100
Grik5RHPRetrohippocampal region100
100
Grik5sAMYStriatum-like amygdalar nuclei100
100
Grik5STRStriatum100
100
Grik5STRdStriatum dorsal region100
100
Grik5STRvStriatum ventral region100
100
Grik5THThalamus100
93.39
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved