AutismKB 2.0

Annotation Detail for MRPL18


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Basic Information Top
Gene Symbol:MRPL18 ( L18mt,MRP-L18 )
Gene Full Name: mitochondrial ribosomal protein L18
Band: 6q25.3
Quick LinksEntrez ID:29074; OMIM: 611831; Uniprot ID:RM18_HUMAN; ENSEMBL ID: ENSG00000112110; HGNC ID: 14477
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus41 / 56401272
neonate3 / 3109796
infant4 / 23620169
juvenile1 / 5555617
adult115 / 193912159
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor13 / 114246113
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor8 / 26384530
glioma17 / 106883159
head and neck tumor1 / 1363027
kidney tumor4 / 6895958
leukemia4 / 9584241
liver tumor7 / 9635972
lung tumor2 / 10312719
lymphoma6 / 7175583
non-neoplasia1 / 9725010
normal224 / 336030766
ovarian tumor3 / 7668239
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer9 / 10268087
retinoblastoma3 / 4635664
skin tumor3 / 12494924
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland8 / 33197240
ascites1 / 4001524
bladder3 / 29757100
blood10 / 12347880
bone5 / 7165569
bone marrow4 / 4880181
brain56 / 110098950
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye7 / 21105433
heart12 / 89626133
intestine22 / 23447293
kidney12 / 21177756
larynx0 / 241450 
liver16 / 20774377
lung19 / 33697456
lymph5 / 44270112
lymph node2 / 9161021
mammary gland12 / 15327178
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary4 / 10205139
pancreas21 / 21481297
parathyroid1 / 2053948
pharynx9 / 41328217
pituitary gland1 / 1658560
placenta8 / 28082528
prostate14 / 18934573
salivary gland2 / 2015599
skin9 / 21057442
spleen0 / 539520 
stomach15 / 96619155
testis12 / 33044236
thymus2 / 8113124
thyroid2 / 4747342
tonsil1 / 1699958
trachea3 / 5241357
umbilical cord2 / 13680146
uterus16 / 23287868
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217907_at
Cell line Expression level Expression bar
721_B_lymphoblasts411.05
Adipocyte122.05
AdrenalCortex71.65
Adrenalgland113.5
Amygdala96.3
Appendix34.15
AtrioventricularNode76.05
BDCA4+_DentriticCells165.4
Bonemarrow69.85
BronchialEpithelialCells288.2
CD105+_Endothelial245.25
CD14+_Monocytes120.2
CD19+_BCells(neg._sel.)184.4
CD33+_Myeloid118.85
CD34+202.8
CD4+_Tcells103
CD56+_NKCells142.95
CD71+_EarlyErythroid142.4
CD8+_Tcells123.35
CardiacMyocytes120.7
Caudatenucleus62
Cerebellum68.8
CerebellumPeduncles56
CiliaryGanglion55.9
CingulateCortex111.7
Colorectaladenocarcinoma153.9
DorsalRootGanglion71.05
FetalThyroid93.75
Fetalbrain82.9
Fetalliver61.2
Fetallung77.3
GlobusPallidus50.65
Heart86.6
Hypothalamus128.15
Kidney74.9
Leukemia_chronicMyelogenousK-562152.45
Leukemia_promyelocytic-HL-60159.75
Leukemialymphoblastic(MOLT-4)189.75
Liver89.5
Lung110.2
Lymphnode81.5
Lymphoma_burkitts(Daudi)204.95
Lymphoma_burkitts(Raji)139.35
MedullaOblongata73.05
OccipitalLobe69.95
OlfactoryBulb128.9
Ovary63.15
Pancreas76.85
PancreaticIslet138.45
ParietalLobe71.6
Pituitary126.7
Placenta91.75
Pons53.55
PrefrontalCortex129.15
Prostate130.35
Salivarygland92.9
SkeletalMuscle35.8
Skin49.05
SmoothMuscle211.4
Spinalcord93.25
SubthalamicNucleus66.7
SuperiorCervicalGanglion53.45
TemporalLobe83.8
Testis136.2
TestisGermCell133.95
TestisIntersitial125.4
TestisLeydigCell100.55
TestisSeminiferousTubule137.95
Thalamus94.55
Thymus115.35
Thyroid93.4
Tongue71.4
Tonsil94.25
Trachea66.65
TrigeminalGanglion45.9
Uterus101.5
UterusCorpus75.2
WholeBlood121.15
Wholebrain232.05
colon85.45
pineal_day127.76
pineal_night126.3
retina103.4
small_intestine101.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7048_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.71 ± 0.52
Basal Forebrain8 ± 0.2
Basal Part of Pons8.43 ± 0.36
Cerebellar Cortex7.94 ± 0.35
Cerebellar Nuclei8.19 ± 0.37
Claustrum7.38 ± 0.49
Epithalamus8.2 ± 0.4
Frontal Lobe8.23 ± 0.38
Globus Pallidus7.86 ± 0.36
Hypothalamus8.25 ± 0.34
Insula8.16 ± 0.3
Limbic Lobe7.85 ± 0.58
Mesencephalon7.87 ± 0.49
Myelencephalon7.94 ± 0.5
Occipital Lobe7.57 ± 0.47
Parietal Lobe8.01 ± 0.47
Pontine Tegmentum8 ± 0.37
Striatum7.7 ± 0.43
Subthalamus8.19 ± 0.44
Temporal Lobe8.12 ± 0.41
Thalamus7.97 ± 0.37
White Matter8.44 ± 0.44
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00490492 9 55 63 NLELLSVAR Peptide Atlas
RM18_HUMAN_120 10 120 129 NVVACESIGR PRIDE
RM18_HUMAN_161 13 161 173 LQSAMTEGGVVLR PRIDE
RM18_HUMAN_54 9 54 62 NLELLSVAR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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