AutismKB 2.0

Annotation Detail for HSPC159


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Basic Information Top
Gene Symbol:HSPC159 ( GRP,MGC33751,MGC71953 )
Gene Full Name: -
Band: 2p14
Quick LinksEntrez ID:29094; OMIM: NA; Uniprot ID:LEGL_HUMAN; ENSEMBL ID: ENSG00000119862; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus25 / 56401244
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult67 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor2 / 17290115
gastrointestinal tumor5 / 11936941
germ cell tumor8 / 26384530
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma4 / 7175555
non-neoplasia6 / 9725061
normal104 / 336030730
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain38 / 110098934
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus2 / 2020998
eye18 / 21105485
heart5 / 8962655
intestine3 / 23447212
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth2 / 6705229
muscle3 / 10771527
nerve0 / 157680 
ovary2 / 10205119
pancreas1 / 2148124
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate11 / 18934558
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach3 / 9661931
testis13 / 33044239
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219998_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.05
Adipocyte4.2
AdrenalCortex4.55
Adrenalgland3.7
Amygdala4.4
Appendix4.25
AtrioventricularNode3.35
BDCA4+_DentriticCells4.55
Bonemarrow4.25
BronchialEpithelialCells4.5
CD105+_Endothelial4.2
CD14+_Monocytes4.5
CD19+_BCells(neg._sel.)4.5
CD33+_Myeloid5.35
CD34+5.3
CD4+_Tcells4.5
CD56+_NKCells4.9
CD71+_EarlyErythroid3.9
CD8+_Tcells4.05
CardiacMyocytes5.25
Caudatenucleus3.8
Cerebellum3.45
CerebellumPeduncles4.8
CiliaryGanglion3.2
CingulateCortex4.3
Colorectaladenocarcinoma4.2
DorsalRootGanglion3.3
FetalThyroid4.1
Fetalbrain4.2
Fetalliver3.65
Fetallung3.4
GlobusPallidus3.15
Heart5.5
Hypothalamus4.6
Kidney3.5
Leukemia_chronicMyelogenousK-5623.75
Leukemia_promyelocytic-HL-603.75
Leukemialymphoblastic(MOLT-4)3.35
Liver5.65
Lung4.6
Lymphnode3.5
Lymphoma_burkitts(Daudi)5.4
Lymphoma_burkitts(Raji)5.85
MedullaOblongata3.85
OccipitalLobe3.8
OlfactoryBulb3.3
Ovary2.8
Pancreas3.4
PancreaticIslet4.55
ParietalLobe4.5
Pituitary4.9
Placenta4.4
Pons4
PrefrontalCortex5.05
Prostate4.9
Salivarygland3.4
SkeletalMuscle5
Skin3.5
SmoothMuscle4.8
Spinalcord4.5
SubthalamicNucleus3.85
SuperiorCervicalGanglion4.8
TemporalLobe3.85
Testis3.6
TestisGermCell3.45
TestisIntersitial3.55
TestisLeydigCell4.2
TestisSeminiferousTubule3.55
Thalamus4.25
Thymus3.25
Thyroid5.25
Tongue4.3
Tonsil4.1
Trachea3.5
TrigeminalGanglion4.4
Uterus3.4
UterusCorpus3.9
WholeBlood4.65
Wholebrain3.6
colon4.25
pineal_day5.16
pineal_night5.1
retina5.15
small_intestine4.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P210330
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.23 ± 0.39
Basal Forebrain9.08 ± 0.26
Basal Part of Pons9.5 ± 0.31
Cerebellar Cortex9.65 ± 0.13
Cerebellar Nuclei9.14 ± 0.39
Claustrum9.03 ± 0.3
Epithalamus8.68 ± 0.37
Frontal Lobe9.34 ± 0.26
Globus Pallidus8.24 ± 0.22
Hypothalamus9.36 ± 0.25
Insula9.48 ± 0.21
Limbic Lobe9.31 ± 0.44
Mesencephalon9.21 ± 0.43
Myelencephalon9.21 ± 0.41
Occipital Lobe9.01 ± 0.43
Parietal Lobe9.35 ± 0.35
Pontine Tegmentum9.18 ± 0.3
Striatum8.91 ± 0.47
Subthalamus9.29 ± 0.06
Temporal Lobe9.4 ± 0.37
Thalamus9.19 ± 0.32
White Matter8.16 ± 0.05
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00351469 19 107 125 GEEQSAIPYFPFIPDQPFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018