AutismKB 2.0

Annotation Detail for FHOD1


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Basic Information Top
Gene Symbol:FHOD1 ( FHOS )
Gene Full Name: formin homology 2 domain containing 1
Band: 16q22.1
Quick LinksEntrez ID:29109; OMIM: 606881; Uniprot ID:FHOD1_HUMAN; ENSEMBL ID: ENSG00000135723; HGNC ID: 17905
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult71 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma14 / 82823169
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor4 / 26384515
glioma6 / 10688356
head and neck tumor12 / 13630288
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal93 / 336030727
ovarian tumor0 / 766820 
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer17 / 102680165
retinoblastoma0 / 463560 
skin tumor13 / 124949104
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood6 / 12347848
bone4 / 7165555
bone marrow7 / 48801143
brain21 / 110098919
cervix0 / 481710 
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye3 / 21105414
heart4 / 8962644
intestine18 / 23447276
kidney2 / 2117779
larynx2 / 2414582
liver2 / 2077439
lung21 / 33697462
lymph0 / 442700 
lymph node2 / 9161021
mammary gland1 / 1532716
mouth1 / 6705214
muscle8 / 10771574
nerve1 / 1576863
ovary1 / 1020519
pancreas20 / 21481293
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate19 / 189345100
salivary gland5 / 20155248
skin13 / 21057461
spleen5 / 5395292
stomach1 / 9661910
testis8 / 33044224
thymus2 / 8113124
thyroid5 / 47473105
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218530_at
Cell line Expression level Expression bar
721_B_lymphoblasts24.05
Adipocyte9.8
AdrenalCortex5.55
Adrenalgland4.45
Amygdala5.6
Appendix5.15
AtrioventricularNode3.8
BDCA4+_DentriticCells6.05
Bonemarrow5.1
BronchialEpithelialCells7.3
CD105+_Endothelial5.3
CD14+_Monocytes18.3
CD19+_BCells(neg._sel.)5.7
CD33+_Myeloid15.05
CD34+10.9
CD4+_Tcells6.05
CD56+_NKCells12.6
CD71+_EarlyErythroid4.85
CD8+_Tcells5.85
CardiacMyocytes7.15
Caudatenucleus4.4
Cerebellum4.15
CerebellumPeduncles5.75
CiliaryGanglion3.55
CingulateCortex5.2
Colorectaladenocarcinoma6.6
DorsalRootGanglion3.95
FetalThyroid6.8
Fetalbrain5.1
Fetalliver4.45
Fetallung30
GlobusPallidus3.75
Heart39.65
Hypothalamus5.65
Kidney4.15
Leukemia_chronicMyelogenousK-56210.85
Leukemia_promyelocytic-HL-608.9
Leukemialymphoblastic(MOLT-4)14.6
Liver6.75
Lung28.1
Lymphnode6.1
Lymphoma_burkitts(Daudi)6.55
Lymphoma_burkitts(Raji)43.75
MedullaOblongata4.7
OccipitalLobe4.65
OlfactoryBulb4.15
Ovary3.45
Pancreas4.15
PancreaticIslet5.6
ParietalLobe5.45
Pituitary5.7
Placenta5.55
Pons4.75
PrefrontalCortex6.45
Prostate6.25
Salivarygland4.15
SkeletalMuscle13.95
Skin3.9
SmoothMuscle5.95
Spinalcord5.6
SubthalamicNucleus4.45
SuperiorCervicalGanglion5.75
TemporalLobe4.7
Testis4.5
TestisGermCell4.45
TestisIntersitial4.35
TestisLeydigCell5.1
TestisSeminiferousTubule4.55
Thalamus4.9
Thymus4.2
Thyroid14.1
Tongue5.05
Tonsil5.1
Trachea4.25
TrigeminalGanglion5.1
Uterus5.15
UterusCorpus4.55
WholeBlood11.45
Wholebrain4.3
colon5.3
pineal_day6.32
pineal_night6.24
retina7.65
small_intestine5.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9141_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.09 ± 0.99
Basal Forebrain1.66 ± 0.24
Basal Part of Pons1.35 ± 0.37
Cerebellar Cortex1.51 ± 0.61
Cerebellar Nuclei1.9 ± 0.72
Claustrum2.52 ± 0.82
Epithalamus1.52 ± 0.73
Frontal Lobe1.48 ± 0.63
Globus Pallidus2.3 ± 0.37
Hypothalamus1.74 ± 0.64
Insula1.62 ± 0.67
Limbic Lobe1.66 ± 0.63
Mesencephalon1.88 ± 0.76
Myelencephalon1.67 ± 0.64
Occipital Lobe1.84 ± 0.7
Parietal Lobe1.63 ± 0.67
Pontine Tegmentum1.73 ± 0.69
Striatum1.88 ± 0.68
Subthalamus1.74 ± 0.64
Temporal Lobe1.52 ± 0.54
Thalamus1.59 ± 0.57
White Matter2.23 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fhod1CBCerebellum11.26
11.84
Fhod1CTXCerebral cortex6.54
4.83
Fhod1HIPHippocampal region3.37
3.28
Fhod1HPFHippocampal formation3.31
2.82
Fhod1HYHypothalamus1.06
0.9
Fhod1LSXLateral septal complex0.2
0.19
Fhod1MBMidbrain2.51
3.03
Fhod1MYMedulla10.43
10.61
Fhod1OLFOlfactory bulb7.12
4.9
Fhod1PPons6.05
5.84
Fhod1PALPallidum3.06
2.55
Fhod1RHPRetrohippocampal region3.24
2.18
Fhod1sAMYStriatum-like amygdalar nuclei1.26
1
Fhod1STRStriatum3.76
2.49
Fhod1STRdStriatum dorsal region5.1
3.37
Fhod1STRvStriatum ventral region2.42
1.59
Fhod1THThalamus3.47
2.52
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
FHOD1_HUMAN_462 19 462 480 AETLAGAMPNEAGGHPDAR PRIDE
FHOD1_HUMAN_887 18 887 904 CAKVDFEQLTENLGQLER PRIDE
PAp00033857 20 647 666 FGPCATLWASLDPVSVDTAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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