AutismKB 2.0

Annotation Detail for TAGLN3


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Basic Information Top
Gene Symbol:TAGLN3 ( NP22,NP25 )
Gene Full Name: transgelin 3
Band: 3q13.2
Quick LinksEntrez ID:29114; OMIM: 607953; Uniprot ID:TAGL3_HUMAN; ENSEMBL ID: ENSG00000144834; HGNC ID: 29868
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus20 / 56401235
neonate0 / 310970 
infant2 / 2362084
juvenile1 / 5555617
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma6 / 10688356
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal106 / 336030731
ovarian tumor0 / 766820 
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain109 / 110098999
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye19 / 21105490
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung17 / 33697450
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204743_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.65
Adipocyte8.2
AdrenalCortex18.8
Adrenalgland17.2
Amygdala329.8
Appendix15.8
AtrioventricularNode12.35
BDCA4+_DentriticCells4.6
Bonemarrow7.2
BronchialEpithelialCells8.15
CD105+_Endothelial8.4
CD14+_Monocytes7.35
CD19+_BCells(neg._sel.)4.55
CD33+_Myeloid10.3
CD34+5.9
CD4+_Tcells5.1
CD56+_NKCells7.3
CD71+_EarlyErythroid4.45
CD8+_Tcells4.5
CardiacMyocytes8.75
Caudatenucleus242.7
Cerebellum221.4
CerebellumPeduncles360.5
CiliaryGanglion53.9
CingulateCortex444.45
Colorectaladenocarcinoma6.25
DorsalRootGanglion59.8
FetalThyroid5.7
Fetalbrain138.1
Fetalliver7.55
Fetallung5.8
GlobusPallidus293.9
Heart11.05
Hypothalamus310.5
Kidney8.35
Leukemia_chronicMyelogenousK-5626.8
Leukemia_promyelocytic-HL-605.15
Leukemialymphoblastic(MOLT-4)6.35
Liver10.6
Lung8.6
Lymphnode6.5
Lymphoma_burkitts(Daudi)8
Lymphoma_burkitts(Raji)8.15
MedullaOblongata474.1
OccipitalLobe344.75
OlfactoryBulb10.05
Ovary10.25
Pancreas6.35
PancreaticIslet34.8
ParietalLobe229.15
Pituitary113.2
Placenta6.7
Pons298.45
PrefrontalCortex519.1
Prostate9.85
Salivarygland7.65
SkeletalMuscle6.7
Skin16.45
SmoothMuscle5.3
Spinalcord72.95
SubthalamicNucleus360.5
SuperiorCervicalGanglion46.35
TemporalLobe524.35
Testis6.85
TestisGermCell6.4
TestisIntersitial7.85
TestisLeydigCell14.15
TestisSeminiferousTubule7.05
Thalamus310.8
Thymus5.4
Thyroid8.05
Tongue9.05
Tonsil6.95
Trachea7.05
TrigeminalGanglion34.7
Uterus7.1
UterusCorpus7.05
WholeBlood6.3
Wholebrain634.15
colon7.05
pineal_day52.44
pineal_night118.88
retina46.875
small_intestine7.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2051_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.16 ± 0.94
Basal Forebrain3.65 ± 0.35
Basal Part of Pons4 ± 0.95
Cerebellar Cortex3.92 ± 0.6
Cerebellar Nuclei4 ± 0.69
Claustrum3.95 ± 0.85
Epithalamus4.03 ± 0.68
Frontal Lobe4.4 ± 0.63
Globus Pallidus2.3 ± 0.7
Hypothalamus3.93 ± 0.66
Insula4.41 ± 0.59
Limbic Lobe4.03 ± 0.86
Mesencephalon4.07 ± 0.79
Myelencephalon4.08 ± 0.71
Occipital Lobe3.24 ± 0.9
Parietal Lobe4.1 ± 0.7
Pontine Tegmentum3.99 ± 0.66
Striatum3.47 ± 0.87
Subthalamus4.06 ± 0.83
Temporal Lobe4.49 ± 0.61
Thalamus3.68 ± 0.68
White Matter2.46 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tagln3CBCerebellum53.98
66.98
Tagln3CTXCerebral cortex100
100
Tagln3HIPHippocampal region91.44
100
Tagln3HPFHippocampal formation100
100
Tagln3HYHypothalamus100
100
Tagln3LSXLateral septal complex100
100
Tagln3MBMidbrain100
100
Tagln3MYMedulla98.65
100
Tagln3OLFOlfactory bulb100
100
Tagln3PPons97.87
100
Tagln3PALPallidum100
88.18
Tagln3RHPRetrohippocampal region100
100
Tagln3sAMYStriatum-like amygdalar nuclei100
100
Tagln3STRStriatum96.93
58.35
Tagln3STRdStriatum dorsal region82.78
40.59
Tagln3STRvStriatum ventral region74.3
39.41
Tagln3THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00074296 20 30 49 LVDWIILQCAEDIEHPPPGR Peptide Atlas
TAGL3_HUMAN_182 14 182 195 GASQAGMTGYGMPR PRIDE
TAGL3_HUMAN_89 10 89 98 QMEQISQFLK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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