AutismKB 2.0

Annotation Detail for ANKRD11


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Basic Information Top
Gene Symbol:ANKRD11 ( ANCO-1,ANCO1,LZ16,T13 )
Gene Full Name: ankyrin repeat domain 11
Band: 16q24.3
Quick LinksEntrez ID:29123; OMIM: 611192; Uniprot ID:ANR11_HUMAN; ENSEMBL ID: ENSG00000167522; HGNC ID: 21316
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body18 / 70761254
blastocyst5 / 6231980
fetus35 / 56401262
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult164 / 193912184
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor5 / 9417853
cervical tumor3 / 3436687
chondrosarcoma11 / 82823132
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor20 / 119369167
germ cell tumor23 / 26384587
glioma8 / 10688374
head and neck tumor14 / 136302102
kidney tumor7 / 68959101
leukemia12 / 95842125
liver tumor2 / 9635920
lung tumor21 / 103127203
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal214 / 336030763
ovarian tumor9 / 76682117
pancreatic tumor19 / 104616181
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer8 / 10268077
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor16 / 125191127
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites14 / 40015349
bladder0 / 297570 
blood8 / 12347864
bone11 / 71655153
bone marrow2 / 4880140
brain33 / 110098929
cervix4 / 4817183
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue28 / 215722129
esophagus0 / 202090 
eye10 / 21105447
heart3 / 8962633
intestine26 / 234472110
kidney22 / 211777103
larynx0 / 241450 
liver22 / 207743105
lung36 / 336974106
lymph1 / 4427022
lymph node18 / 91610196
mammary gland9 / 15327158
mouth8 / 67052119
muscle14 / 107715129
nerve1 / 1576863
ovary10 / 10205197
pancreas30 / 214812139
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate20 / 189345105
salivary gland1 / 2015549
skin10 / 21057447
spleen2 / 5395237
stomach5 / 9661951
testis9 / 33044227
thymus3 / 8113136
thyroid6 / 47473126
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219437_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts38.1
Adipocyte16.95
AdrenalCortex20.2
Adrenalgland14.95
Amygdala32.6
Appendix15.5
AtrioventricularNode13.1
BDCA4+_DentriticCells31.15
Bonemarrow17
BronchialEpithelialCells22.55
CD105+_Endothelial16.8
CD14+_Monocytes20.35
CD19+_BCells(neg._sel.)17.2
CD33+_Myeloid55.7
CD34+21.5
CD4+_Tcells131.8
CD56+_NKCells20.45
CD71+_EarlyErythroid10.95
CD8+_Tcells136.45
CardiacMyocytes25.55
Caudatenucleus15.35
Cerebellum13.9
CerebellumPeduncles23.95
CiliaryGanglion12.8
CingulateCortex26.1
Colorectaladenocarcinoma19.25
DorsalRootGanglion13.1
FetalThyroid22.7
Fetalbrain17.1
Fetalliver14.5
Fetallung10.15
GlobusPallidus13.1
Heart22.4
Hypothalamus17.3
Kidney14.45
Leukemia_chronicMyelogenousK-56217.35
Leukemia_promyelocytic-HL-6013.2
Leukemialymphoblastic(MOLT-4)23.25
Liver15.5
Lung23.55
Lymphnode14.05
Lymphoma_burkitts(Daudi)21.55
Lymphoma_burkitts(Raji)34.8
MedullaOblongata16.55
OccipitalLobe16
OlfactoryBulb13.4
Ovary6.2
Pancreas17.7
PancreaticIslet18.2
ParietalLobe33.55
Pituitary19.7
Placenta16.7
Pons16.2
PrefrontalCortex21.15
Prostate53.8
Salivarygland8.7
SkeletalMuscle26.5
Skin13.75
SmoothMuscle43.55
Spinalcord13.95
SubthalamicNucleus23.2
SuperiorCervicalGanglion12.6
TemporalLobe16.8
Testis14.4
TestisGermCell18.25
TestisIntersitial12.2
TestisLeydigCell11.95
TestisSeminiferousTubule14.5
Thalamus8.75
Thymus52.65
Thyroid20.2
Tongue17.45
Tonsil51.4
Trachea14.35
TrigeminalGanglion8.3
Uterus26.75
UterusCorpus16
WholeBlood14.95
Wholebrain17.9
colon16.9
pineal_day20.68
pineal_night20.24
retina15.25
small_intestine16.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P3632
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.34 ± 0.27
Basal Forebrain11.06 ± 0.17
Basal Part of Pons11.03 ± 0.18
Cerebellar Cortex11.12 ± 0.34
Cerebellar Nuclei11.01 ± 0.29
Claustrum11.29 ± 0.23
Epithalamus11.09 ± 0.4
Frontal Lobe11.09 ± 0.3
Globus Pallidus11.06 ± 0.3
Hypothalamus10.84 ± 0.29
Insula11.22 ± 0.3
Limbic Lobe11.35 ± 0.31
Mesencephalon11.07 ± 0.25
Myelencephalon11.12 ± 0.22
Occipital Lobe11.22 ± 0.19
Parietal Lobe11.19 ± 0.28
Pontine Tegmentum11.13 ± 0.26
Striatum11.14 ± 0.26
Subthalamus11.06 ± 0.15
Temporal Lobe11.27 ± 0.27
Thalamus10.93 ± 0.22
White Matter11.6 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ankrd11CBCerebellum38.85
49.1
Ankrd11CTXCerebral cortex100
89.08
Ankrd11HIPHippocampal region56.99
81.76
Ankrd11HPFHippocampal formation67.58
77.92
Ankrd11HYHypothalamus78.26
66.66
Ankrd11LSXLateral septal complex100
89.3
Ankrd11MBMidbrain61.62
57.97
Ankrd11MYMedulla68.64
77.47
Ankrd11OLFOlfactory bulb100
94.04
Ankrd11PPons67.78
73.45
Ankrd11PALPallidum73.68
71.47
Ankrd11RHPRetrohippocampal region86.9
75.47
Ankrd11sAMYStriatum-like amygdalar nuclei86.73
68.65
Ankrd11STRStriatum86.06
67.84
Ankrd11STRdStriatum dorsal region79.62
62.36
Ankrd11STRvStriatum ventral region100
79.94
Ankrd11THThalamus75.99
68.93
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ANR11_HUMAN_1587 12 1587 1598 MLSQKDLEIEER PRIDE
ANR11_HUMAN_690 7 690 696 HDRDHFK PRIDE
PAp00009794 14 198 211 DFAGWTALHEACNR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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