AutismKB 2.0

Annotation Detail for SLC25A6


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Basic Information Top
Gene Symbol:SLC25A6 ( AAC3,ANT3,ANT3Y,MGC17525 )
Gene Full Name: solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
Band: Xp22.32 and Yp11.3
Quick LinksEntrez ID:293; OMIM: 300151,403000; Uniprot ID:ADT3_HUMAN; ENSEMBL ID: ENSG00000169100; HGNC ID: 10992
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body51 / 70761720
blastocyst82 / 623191315
fetus169 / 564012299
neonate9 / 31097289
infant19 / 23620804
juvenile16 / 55556287
adult866 / 1939121446
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor10 / 12794781
bladder carcinoma2 / 17475114
breast (mammary gland) tumor55 / 94178584
cervical tumor69 / 343662007
chondrosarcoma18 / 82823217
colorectal tumor80 / 114246700
esophageal tumor5 / 17290289
gastrointestinal tumor96 / 119369804
germ cell tumor160 / 263845606
glioma76 / 106883711
head and neck tumor46 / 136302337
kidney tumor35 / 68959507
leukemia55 / 95842573
liver tumor119 / 963591234
lung tumor238 / 1031272307
lymphoma80 / 717551114
non-neoplasia16 / 97250164
normal1237 / 3360307368
ovarian tumor46 / 76682599
pancreatic tumor62 / 104616592
primitive neuroectodermal tumor of the CNS113 / 125680899
prostate cancer130 / 1026801266
retinoblastoma51 / 463561100
skin tumor74 / 124949592
soft tissue/muscle tissue tumor121 / 125191966
uterine tumor57 / 90257631
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue16 / 131061220
adrenal gland14 / 33197421
ascites34 / 40015849
bladder14 / 29757470
blood51 / 123478413
bone21 / 71655293
bone marrow33 / 48801676
brain399 / 1100989362
cervix77 / 481711598
connective tissue24 / 149255160
ear4 / 16212246
embryonic tissue229 / 2157221061
esophagus6 / 20209296
eye130 / 211054615
heart21 / 89626234
intestine127 / 234472541
kidney60 / 211777283
larynx12 / 24145496
liver179 / 207743861
lung322 / 336974955
lymph68 / 442701536
lymph node25 / 91610272
mammary gland85 / 153271554
mouth31 / 67052462
muscle88 / 107715816
nerve11 / 15768697
ovary67 / 102051656
pancreas88 / 214812409
parathyroid6 / 20539292
pharynx11 / 41328266
pituitary gland10 / 16585602
placenta92 / 280825327
prostate150 / 189345792
salivary gland23 / 201551141
skin113 / 210574536
spleen11 / 53952203
stomach86 / 96619890
testis73 / 330442220
thymus21 / 81131258
thyroid19 / 47473400
tonsil9 / 16999529
trachea2 / 5241338
umbilical cord4 / 13680292
uterus113 / 232878485
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212085_at
Cell line Expression level Expression bar
721_B_lymphoblasts3933.95
Adipocyte892.05
AdrenalCortex741
Adrenalgland465.6
Amygdala701.65
Appendix279.35
AtrioventricularNode65.8
BDCA4+_DentriticCells3126.7
Bonemarrow470.8
BronchialEpithelialCells1337.9
CD105+_Endothelial1693.45
CD14+_Monocytes2650.6
CD19+_BCells(neg._sel.)2996.05
CD33+_Myeloid3329.05
CD34+3342.55
CD4+_Tcells2829
CD56+_NKCells2203
CD71+_EarlyErythroid713.85
CD8+_Tcells2429.85
CardiacMyocytes1194.2
Caudatenucleus373.05
Cerebellum324.8
CerebellumPeduncles795.75
CiliaryGanglion81
CingulateCortex292.6
Colorectaladenocarcinoma1861
DorsalRootGanglion88.1
FetalThyroid1038.05
Fetalbrain685.7
Fetalliver262.35
Fetallung1058.8
GlobusPallidus189.3
Heart901.35
Hypothalamus555.25
Kidney402.15
Leukemia_chronicMyelogenousK-5621359.9
Leukemia_promyelocytic-HL-601817.3
Leukemialymphoblastic(MOLT-4)1283.05
Liver496.65
Lung2310.9
Lymphnode781.2
Lymphoma_burkitts(Daudi)3446.05
Lymphoma_burkitts(Raji)6418.2
MedullaOblongata360.45
OccipitalLobe425.15
OlfactoryBulb218.35
Ovary944.15
Pancreas1223.3
PancreaticIslet1379.15
ParietalLobe325.05
Pituitary621.75
Placenta639.6
Pons273.3
PrefrontalCortex660.15
Prostate2079.75
Salivarygland580.8
SkeletalMuscle26.05
Skin211
SmoothMuscle1693.05
Spinalcord190.9
SubthalamicNucleus237.7
SuperiorCervicalGanglion33
TemporalLobe561.75
Testis128.75
TestisGermCell333.1
TestisIntersitial78.9
TestisLeydigCell95.35
TestisSeminiferousTubule96.55
Thalamus365.45
Thymus1225.45
Thyroid3241.4
Tongue244.35
Tonsil881.05
Trachea499.75
TrigeminalGanglion58.05
Uterus1176.95
UterusCorpus792.2
WholeBlood1152.85
Wholebrain1039.1
colon956.35
pineal_day1424.98
pineal_night1326.86
retina1219.85
small_intestine880.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P24794
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.93 ± 0.35
Basal Forebrain5.81 ± 0.25
Basal Part of Pons5.72 ± 0.35
Cerebellar Cortex5.47 ± 0.22
Cerebellar Nuclei6.06 ± 0.42
Claustrum6.01 ± 0.38
Epithalamus4.92 ± 0.35
Frontal Lobe5.66 ± 0.33
Globus Pallidus5.99 ± 0.33
Hypothalamus5.53 ± 0.32
Insula5.47 ± 0.32
Limbic Lobe5.69 ± 0.36
Mesencephalon5.74 ± 0.36
Myelencephalon5.77 ± 0.4
Occipital Lobe5.9 ± 0.4
Parietal Lobe5.75 ± 0.4
Pontine Tegmentum5.67 ± 0.35
Striatum6.15 ± 0.34
Subthalamus5.97 ± 0.11
Temporal Lobe5.66 ± 0.33
Thalamus5.92 ± 0.28
White Matter5.17 ± 0.08
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ADT3_HUMAN_0 0 0 0 GLGDCLVK PRIDE
ADT3_HUMAN_0 0 0 0 GNLANVIR PRIDE
ADT3_HUMAN_0 0 0 0 YFPTQALNFAFK PRIDE
ADT3_HUMAN_10 13 10 22 DFLAGGIAAAISK PRIDE
ADT3_HUMAN_155 8 155 162 GLGDCLVK PRIDE
ADT3_HUMAN_189 11 189 199 AAYFGVYDTAK PRIDE
ADT3_HUMAN_2 19 2 20 TEQAISFAKDFLAGGIAAA PRIDE
ADT3_HUMAN_273 8 273 280 GAWSNVLR PRIDE
ADT3_HUMAN_33 10 33 42 LLLQVQHASK PRIDE
ADT3_HUMAN_72 8 72 79 GNLANVIR PRIDE
ADT3_HUMAN_80 12 80 91 YFPTQALNFAFK PRIDE
ADT3_HUMAN_81 12 81 92 YFPTQALNFAFK PRIDE
PAp00002184 9 64 72 EQGVLSFWR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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