AutismKB 2.0

Annotation Detail for GSPT1


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Basic Information Top
Gene Symbol:GSPT1 ( 551G9.2,ETF3A,FLJ38048,FLJ39067,GST1,eRF3a )
Gene Full Name: G1 to S phase transition 1
Band: 16p13.13
Quick LinksEntrez ID:2935; OMIM: 139259; Uniprot ID:ERF3A_HUMAN; ENSEMBL ID: ENSG00000103342; HGNC ID: 4621
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst6 / 6231996
fetus38 / 56401267
neonate4 / 31097128
infant1 / 2362042
juvenile8 / 55556143
adult247 / 1939121127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma2 / 17475114
breast (mammary gland) tumor14 / 94178148
cervical tumor13 / 34366378
chondrosarcoma9 / 82823108
colorectal tumor25 / 114246218
esophageal tumor0 / 172900 
gastrointestinal tumor13 / 119369108
germ cell tumor40 / 263845151
glioma10 / 10688393
head and neck tumor12 / 13630288
kidney tumor6 / 6895987
leukemia8 / 9584283
liver tumor8 / 9635983
lung tumor13 / 103127126
lymphoma6 / 7175583
non-neoplasia5 / 9725051
normal292 / 336030786
ovarian tumor8 / 76682104
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer24 / 102680233
retinoblastoma10 / 46356215
skin tumor17 / 124949136
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland6 / 33197180
ascites4 / 4001599
bladder3 / 29757100
blood9 / 12347872
bone6 / 7165583
bone marrow2 / 4880140
brain65 / 110098959
cervix14 / 48171290
connective tissue8 / 14925553
ear2 / 16212123
embryonic tissue21 / 21572297
esophagus1 / 2020949
eye23 / 211054108
heart12 / 89626133
intestine35 / 234472149
kidney15 / 21177770
larynx4 / 24145165
liver21 / 207743101
lung36 / 336974106
lymph5 / 44270112
lymph node8 / 9161087
mammary gland21 / 153271137
mouth2 / 6705229
muscle10 / 10771592
nerve1 / 1576863
ovary9 / 10205188
pancreas18 / 21481283
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta26 / 28082592
prostate43 / 189345227
salivary gland2 / 2015599
skin22 / 210574104
spleen7 / 53952129
stomach8 / 9661982
testis61 / 330442184
thymus2 / 8113124
thyroid10 / 47473210
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord2 / 13680146
uterus26 / 232878111
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201912_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts469.9
Adipocyte72.25
AdrenalCortex17.25
Adrenalgland22.4
Amygdala24.5
Appendix20.5
AtrioventricularNode13.55
BDCA4+_DentriticCells103.7
Bonemarrow225.95
BronchialEpithelialCells295
CD105+_Endothelial304.65
CD14+_Monocytes30.85
CD19+_BCells(neg._sel.)57.5
CD33+_Myeloid63.65
CD34+178
CD4+_Tcells75.5
CD56+_NKCells51.55
CD71+_EarlyErythroid679.7
CD8+_Tcells55.25
CardiacMyocytes68.35
Caudatenucleus11.7
Cerebellum9.85
CerebellumPeduncles14.35
CiliaryGanglion12.15
CingulateCortex18.15
Colorectaladenocarcinoma62.6
DorsalRootGanglion10.35
FetalThyroid15.75
Fetalbrain17
Fetalliver109.2
Fetallung51.25
GlobusPallidus14.15
Heart26.3
Hypothalamus22.1
Kidney18.85
Leukemia_chronicMyelogenousK-562176.85
Leukemia_promyelocytic-HL-60188.15
Leukemialymphoblastic(MOLT-4)54.55
Liver25.85
Lung30.5
Lymphnode17.8
Lymphoma_burkitts(Daudi)241.7
Lymphoma_burkitts(Raji)81.05
MedullaOblongata15.85
OccipitalLobe15.8
OlfactoryBulb21.65
Ovary12.15
Pancreas20
PancreaticIslet66.6
ParietalLobe13.8
Pituitary22.3
Placenta75.05
Pons12.5
PrefrontalCortex20.65
Prostate39
Salivarygland16.4
SkeletalMuscle19.15
Skin17.9
SmoothMuscle128.65
Spinalcord19.75
SubthalamicNucleus14.9
SuperiorCervicalGanglion17.45
TemporalLobe12.7
Testis44.65
TestisGermCell43.8
TestisIntersitial44.9
TestisLeydigCell53.65
TestisSeminiferousTubule28.8
Thalamus16.9
Thymus35.65
Thyroid65.75
Tongue15.9
Tonsil29.15
Trachea34.6
TrigeminalGanglion15.05
Uterus23.05
UterusCorpus16.6
WholeBlood45.45
Wholebrain13.55
colon67.2
pineal_day45.74
pineal_night54.32
retina27.8
small_intestine62.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P206301
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.94 ± 0.39
Basal Forebrain4.89 ± 0.22
Basal Part of Pons4.86 ± 0.29
Cerebellar Cortex4.68 ± 0.53
Cerebellar Nuclei4.75 ± 0.34
Claustrum4.65 ± 0.65
Epithalamus4.62 ± 0.24
Frontal Lobe4.77 ± 0.37
Globus Pallidus5 ± 0.23
Hypothalamus4.59 ± 0.56
Insula4.85 ± 0.31
Limbic Lobe4.78 ± 0.47
Mesencephalon4.88 ± 0.4
Myelencephalon4.76 ± 0.45
Occipital Lobe4.97 ± 0.3
Parietal Lobe4.82 ± 0.42
Pontine Tegmentum4.81 ± 0.45
Striatum4.86 ± 0.3
Subthalamus5.12 ± 0.14
Temporal Lobe4.78 ± 0.4
Thalamus4.79 ± 0.42
White Matter5.51 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gspt1CBCerebellum20.56
31.55
Gspt1CTXCerebral cortex30.06
23.57
Gspt1HIPHippocampal region34.88
53.29
Gspt1HPFHippocampal formation35.14
42.79
Gspt1HYHypothalamus2.47
2.1
Gspt1LSXLateral septal complex6.03
4.52
Gspt1MBMidbrain7.25
7.88
Gspt1MYMedulla16.24
20.65
Gspt1OLFOlfactory bulb17.19
14.12
Gspt1PPons10.4
13.89
Gspt1PALPallidum6.79
6.97
Gspt1RHPRetrohippocampal region37.61
30.79
Gspt1sAMYStriatum-like amygdalar nuclei3.91
2.77
Gspt1STRStriatum10.29
7.62
Gspt1STRdStriatum dorsal region13.55
10.22
Gspt1STRvStriatum ventral region5.61
4.08
Gspt1THThalamus13.16
12.83
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ERF3A_HUMAN_164 23 164 186 SFVPNMIGGASQADLAVLVISAR PRIDE
ERF3A_HUMAN_329 10 329 338 GQQLVMMPNK PRIDE
ERF3A_HUMAN_71 16 71 86 KEHVNVVFIGHVDAGK PRIDE
PAp00002613 11 446 456 FVKQDQVCIAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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