AutismKB 2.0

Annotation Detail for GSTM3


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Basic Information Top
Gene Symbol:GSTM3 ( GST5,GSTB,GSTM3-3,GTM3,MGC3310,MGC3704 )
Gene Full Name: glutathione S-transferase mu 3 (brain)
Band: 1p13.3
Quick LinksEntrez ID:2947; OMIM: 138390; Uniprot ID:GSTM3_HUMAN; ENSEMBL ID: ENSG00000134202; HGNC ID: 4635
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus33 / 56401258
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult115 / 193912159
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma5 / 17475286
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma12 / 82823144
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor13 / 26384549
glioma11 / 106883102
head and neck tumor4 / 13630229
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor10 / 10312796
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal272 / 336030780
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer6 / 10268058
retinoblastoma3 / 4635664
skin tumor10 / 12494980
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites9 / 40015224
bladder4 / 29757134
blood71 / 123478575
bone2 / 7165527
bone marrow0 / 488010 
brain81 / 110098973
cervix2 / 4817141
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye19 / 21105490
heart3 / 8962633
intestine12 / 23447251
kidney11 / 21177751
larynx0 / 241450 
liver16 / 20774377
lung23 / 33697468
lymph0 / 442700 
lymph node1 / 9161010
mammary gland9 / 15327158
mouth2 / 6705229
muscle4 / 10771537
nerve1 / 1576863
ovary3 / 10205129
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta16 / 28082556
prostate17 / 18934589
salivary gland0 / 201550 
skin12 / 21057456
spleen0 / 539520 
stomach1 / 9661910
testis45 / 330442136
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202554_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.25
Adipocyte83.85
AdrenalCortex39.55
Adrenalgland90.65
Amygdala221.45
Appendix42.8
AtrioventricularNode33.8
BDCA4+_DentriticCells11.55
Bonemarrow25.05
BronchialEpithelialCells45.25
CD105+_Endothelial52.8
CD14+_Monocytes11.05
CD19+_BCells(neg._sel.)10.65
CD33+_Myeloid12.3
CD34+15.9
CD4+_Tcells12.8
CD56+_NKCells13.8
CD71+_EarlyErythroid9.85
CD8+_Tcells21.8
CardiacMyocytes37.05
Caudatenucleus183.05
Cerebellum57.3
CerebellumPeduncles103.45
CiliaryGanglion42.7
CingulateCortex140.2
Colorectaladenocarcinoma6.05
DorsalRootGanglion34.3
FetalThyroid98.95
Fetalbrain122.85
Fetalliver39
Fetallung78.15
GlobusPallidus87.95
Heart355.2
Hypothalamus191.65
Kidney354.5
Leukemia_chronicMyelogenousK-56243.4
Leukemia_promyelocytic-HL-608.95
Leukemialymphoblastic(MOLT-4)92.25
Liver76.8
Lung30.35
Lymphnode19.3
Lymphoma_burkitts(Daudi)15.9
Lymphoma_burkitts(Raji)23.65
MedullaOblongata131.6
OccipitalLobe143.1
OlfactoryBulb152.9
Ovary285.15
Pancreas55.7
PancreaticIslet98
ParietalLobe104.35
Pituitary164.95
Placenta15.4
Pons148.65
PrefrontalCortex300.65
Prostate96.35
Salivarygland27.55
SkeletalMuscle40.7
Skin42.5
SmoothMuscle408.05
Spinalcord184.2
SubthalamicNucleus115.1
SuperiorCervicalGanglion39.5
TemporalLobe126.35
Testis4132.65
TestisGermCell4653.1
TestisIntersitial3685.25
TestisLeydigCell3222.1
TestisSeminiferousTubule2788.4
Thalamus147.35
Thymus27
Thyroid211.8
Tongue40.2
Tonsil32.5
Trachea48.05
TrigeminalGanglion58.9
Uterus36.7
UterusCorpus21.35
WholeBlood10.35
Wholebrain310.7
colon30.6
pineal_day143.66
pineal_night187.64
retina293.675
small_intestine195.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P12343
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala12.25 ± 0.21
Basal Forebrain12.17 ± 0.11
Basal Part of Pons11.64 ± 0.34
Cerebellar Cortex11.41 ± 0.15
Cerebellar Nuclei11.67 ± 0.18
Claustrum11.97 ± 0.28
Epithalamus12.15 ± 0.32
Frontal Lobe11.77 ± 0.33
Globus Pallidus12.18 ± 0.16
Hypothalamus12.37 ± 0.26
Insula12.03 ± 0.2
Limbic Lobe11.69 ± 0.38
Mesencephalon11.74 ± 0.32
Myelencephalon11.82 ± 0.36
Occipital Lobe11.54 ± 0.28
Parietal Lobe11.74 ± 0.27
Pontine Tegmentum11.82 ± 0.46
Striatum12.41 ± 0.24
Subthalamus11.73 ± 0.23
Temporal Lobe11.78 ± 0.33
Thalamus11.56 ± 0.32
White Matter10.82 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gstm3CBCerebellum43.73
64.36
Gstm3CTXCerebral cortex35.91
26.82
Gstm3HIPHippocampal region31.37
43.46
Gstm3HPFHippocampal formation36.55
37.85
Gstm3HYHypothalamus27.83
24.58
Gstm3LSXLateral septal complex12.05
13.4
Gstm3MBMidbrain30.84
29.74
Gstm3MYMedulla18.2
19.65
Gstm3OLFOlfactory bulb45.63
40.68
Gstm3PPons15.81
15.24
Gstm3PALPallidum16.61
14.08
Gstm3RHPRetrohippocampal region43.01
32.74
Gstm3sAMYStriatum-like amygdalar nuclei45.57
33.06
Gstm3STRStriatum16.51
14.08
Gstm3STRdStriatum dorsal region8.55
6.37
Gstm3STRvStriatum ventral region26.24
20.84
Gstm3THThalamus17.43
15.33
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GSTM3_HUMAN_100 12 100 111 VDIIENQVMDFR PRIDE
GSTM3_HUMAN_140 8 140 147 QFSMFLGK PRIDE
GSTM3_HUMAN_156 16 156 171 LTFVDFLTYDILDQNR PRIDE
GSTM3_HUMAN_197 12 197 208 IAAYLQSDQFCK PRIDE
GSTM3_HUMAN_215 10 215 224 MAQWGNKPVC PRIDE
GSTM3_HUMAN_22 13 22 34 LLLEFTDTSYEEK PRIDE
GSTM3_HUMAN_54 17 54 70 FKLDLDFPNLPYLLDGK PRIDE
GSTM3_HUMAN_56 15 56 70 LDLDFPNLPYLLDGK PRIDE
GSTM3_HUMAN_73 9 73 81 ITQSNAILR PRIDE
PAp00009547 9 178 186 CLDEFPNLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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