AutismKB 2.0

Annotation Detail for GSTP1


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Basic Information Top
Gene Symbol:GSTP1 ( DFN7,FAEES3,GST3,GSTP,PI )
Gene Full Name: glutathione S-transferase pi 1
Band: 11q13.2
Quick LinksEntrez ID:2950; OMIM: 134660; Uniprot ID:GSTP1_HUMAN; ENSEMBL ID: ENSG00000084207; HGNC ID: 4638
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body35 / 70761494
blastocyst11 / 62319176
fetus76 / 564012134
neonate4 / 31097128
infant2 / 2362084
juvenile8 / 55556143
adult576 / 1939121297
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor17 / 94178180
cervical tumor1 / 3436629
chondrosarcoma15 / 82823181
colorectal tumor96 / 114246840
esophageal tumor2 / 17290115
gastrointestinal tumor80 / 119369670
germ cell tumor38 / 263845144
glioma27 / 106883252
head and neck tumor80 / 136302586
kidney tumor9 / 68959130
leukemia20 / 95842208
liver tumor6 / 9635962
lung tumor33 / 103127319
lymphoma15 / 71755209
non-neoplasia17 / 97250174
normal550 / 3360307163
ovarian tumor26 / 76682339
pancreatic tumor51 / 104616487
primitive neuroectodermal tumor of the CNS39 / 125680310
prostate cancer9 / 10268087
retinoblastoma32 / 46356690
skin tumor22 / 124949176
soft tissue/muscle tissue tumor18 / 125191143
uterine tumor38 / 90257421
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland6 / 33197180
ascites67 / 400151674
bladder4 / 29757134
blood24 / 123478194
bone15 / 71655209
bone marrow4 / 4880181
brain94 / 110098985
cervix3 / 4817162
connective tissue15 / 149255100
ear0 / 162120 
embryonic tissue66 / 215722305
esophagus2 / 2020998
eye94 / 211054445
heart16 / 89626178
intestine119 / 234472507
kidney29 / 211777136
larynx4 / 24145165
liver13 / 20774362
lung85 / 336974252
lymph11 / 44270248
lymph node11 / 91610120
mammary gland30 / 153271195
mouth29 / 67052432
muscle18 / 107715167
nerve1 / 1576863
ovary36 / 102051352
pancreas60 / 214812279
parathyroid3 / 20539146
pharynx31 / 41328750
pituitary gland4 / 16585241
placenta109 / 280825388
prostate37 / 189345195
salivary gland6 / 20155297
skin40 / 210574189
spleen3 / 5395255
stomach31 / 96619320
testis17 / 33044251
thymus1 / 8113112
thyroid15 / 47473315
tonsil7 / 16999411
trachea0 / 524130 
umbilical cord4 / 13680292
uterus70 / 232878300
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200824_at
Cell line Expression level Expression bar
721_B_lymphoblasts1372.9
Adipocyte235.55
AdrenalCortex185.8
Adrenalgland203.7
Amygdala76.55
Appendix149.7
AtrioventricularNode92.95
BDCA4+_DentriticCells398.4
Bonemarrow344.15
BronchialEpithelialCells1902.95
CD105+_Endothelial39.1
CD14+_Monocytes610
CD19+_BCells(neg._sel.)122.4
CD33+_Myeloid393.6
CD34+287.15
CD4+_Tcells43.8
CD56+_NKCells185.05
CD71+_EarlyErythroid61.15
CD8+_Tcells83.9
CardiacMyocytes681.05
Caudatenucleus159.05
Cerebellum119.85
CerebellumPeduncles307.9
CiliaryGanglion107.5
CingulateCortex218.65
Colorectaladenocarcinoma886.45
DorsalRootGanglion111.8
FetalThyroid841.05
Fetalbrain154.35
Fetalliver194.3
Fetallung471.2
GlobusPallidus92.1
Heart883.95
Hypothalamus235.8
Kidney285.55
Leukemia_chronicMyelogenousK-562285.05
Leukemia_promyelocytic-HL-6055.2
Leukemialymphoblastic(MOLT-4)631.65
Liver52.35
Lung972.6
Lymphnode230.95
Lymphoma_burkitts(Daudi)67.3
Lymphoma_burkitts(Raji)20.6
MedullaOblongata103.55
OccipitalLobe152.35
OlfactoryBulb254.45
Ovary187.7
Pancreas487.65
PancreaticIslet270.4
ParietalLobe153.35
Pituitary539.55
Placenta862.1
Pons140.25
PrefrontalCortex177.4
Prostate383.8
Salivarygland137.5
SkeletalMuscle135.65
Skin107.8
SmoothMuscle981
Spinalcord279.25
SubthalamicNucleus93.9
SuperiorCervicalGanglion38.8
TemporalLobe110.7
Testis89.25
TestisGermCell34.5
TestisIntersitial69.95
TestisLeydigCell95.3
TestisSeminiferousTubule72.25
Thalamus280.3
Thymus410.9
Thyroid1004.7
Tongue616.95
Tonsil330.7
Trachea404.85
TrigeminalGanglion124.5
Uterus272
UterusCorpus212.7
WholeBlood349.3
Wholebrain173.15
colon208.7
pineal_day1063
pineal_night948.78
retina756.6
small_intestine332.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16952_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.64 ± 0.32
Basal Forebrain9.95 ± 0.16
Basal Part of Pons9.85 ± 0.29
Cerebellar Cortex9.73 ± 0.26
Cerebellar Nuclei9.8 ± 0.33
Claustrum9.34 ± 0.53
Epithalamus10.54 ± 0.33
Frontal Lobe9.91 ± 0.36
Globus Pallidus10.78 ± 0.32
Hypothalamus10.41 ± 0.14
Insula9.85 ± 0.33
Limbic Lobe9.51 ± 0.44
Mesencephalon9.85 ± 0.38
Myelencephalon9.89 ± 0.35
Occipital Lobe9.37 ± 0.28
Parietal Lobe9.71 ± 0.34
Pontine Tegmentum9.87 ± 0.39
Striatum10.04 ± 0.27
Subthalamus9.95 ± 0.25
Temporal Lobe9.8 ± 0.35
Thalamus9.97 ± 0.25
White Matter10.62 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gstp1CBCerebellum71.84
98.18
Gstp1CTXCerebral cortex100
100
Gstp1HIPHippocampal region100
100
Gstp1HPFHippocampal formation100
100
Gstp1HYHypothalamus100
100
Gstp1LSXLateral septal complex100
100
Gstp1MBMidbrain100
100
Gstp1MYMedulla97.74
100
Gstp1OLFOlfactory bulb100
100
Gstp1PPons99.27
100
Gstp1PALPallidum100
100
Gstp1RHPRetrohippocampal region100
100
Gstp1sAMYStriatum-like amygdalar nuclei100
100
Gstp1STRStriatum100
100
Gstp1STRdStriatum dorsal region100
92.41
Gstp1STRvStriatum ventral region100
100
Gstp1THThalamus82.18
78.26
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GSTP1_HUMAN_0 0 0 0 ALPGQLKPFETLLSQNQGGK PRIDE
GSTP1_HUMAN_0 0 0 0 FQDGDLTLYQSNTILR PRIDE
GSTP1_HUMAN_0 0 0 0 MPPYTVVYFPVR PRIDE
GSTP1_HUMAN_0 0 0 0 YISLIYTNYEAGKDDYVK PRIDE
GSTP1_HUMAN_1 11 1 11 PPYTVVYFPVR PRIDE
GSTP1_HUMAN_1 12 1 12 MPPYTVVYFPVR PRIDE
GSTP1_HUMAN_103 13 103 115 YISLIYTNYEAGK PRIDE
GSTP1_HUMAN_103 18 103 120 YISLIYTNYEAGKDDYVK PRIDE
GSTP1_HUMAN_121 20 121 140 ALPGQLKPFETLLSQNQGGK PRIDE
GSTP1_HUMAN_169 14 169 182 CLDAFPLLSAYVGR PRIDE
GSTP1_HUMAN_187 23 187 209 PKLKAFLASPEYVNLPINGNGKQ PRIDE
GSTP1_HUMAN_188 23 188 210 PKLKAFLASPEYVNLPINGNGKQ PRIDE
GSTP1_HUMAN_19 11 19 29 MLLADQGQSWK PRIDE
GSTP1_HUMAN_19 26 19 44 MLLADQGQSWKEEVVTVETWQEGSLK PRIDE
GSTP1_HUMAN_2 11 2 12 PPYTVVYFPVR PRIDE
GSTP1_HUMAN_30 15 30 44 EEVVTVETWQEGSLK PRIDE
GSTP1_HUMAN_45 10 45 54 ASCLYGQLPK PRIDE
GSTP1_HUMAN_45 26 45 70 ASCLYGQLPKFQDGDLTLYQSNTILR PRIDE
GSTP1_HUMAN_55 16 55 70 FQDGDLTLYQSNTILR PRIDE
GSTP1_HUMAN_75 26 75 100 TLGLYGKDQQEAALVDMVNDGVEDLR PRIDE
GSTP1_HUMAN_75 28 75 102 TLGLYGKDQQEAALVDMVNDGVEDLRCK PRIDE
GSTP1_HUMAN_76 26 76 101 TLGLYGKDQQEAALVDMVNDGVEDLR PRIDE
GSTP1_HUMAN_81 20 81 100 KDQQEAALVDMVNDGVEDLR PRIDE
GSTP1_HUMAN_82 19 82 100 DQQEAALVDMVNDGVEDLR PRIDE
GSTP1_HUMAN_82 21 82 102 DQQEAALVDMVNDGVEDLRCK PRIDE
PAp00000549 20 122 141 ALPGQLKPFETLLSQNQGGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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