AutismKB 2.0

Annotation Detail for GSTT1


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Basic Information Top
Gene Symbol:GSTT1 ( - )
Gene Full Name: glutathione S-transferase theta 1
Band: 22q11.23 alternate reference locus
Quick LinksEntrez ID:2952; OMIM: 600436; Uniprot ID:GSTT1_HUMAN; ENSEMBL ID: ENSG00000184674; HGNC ID: 4641
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult93 / 193912147
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma4 / 10688337
head and neck tumor6 / 13630244
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor13 / 96359134
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal140 / 336030741
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder3 / 29757100
blood1 / 1234788
bone4 / 7165555
bone marrow0 / 488010 
brain18 / 110098916
cervix3 / 4817162
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye1 / 2110544
heart4 / 8962644
intestine11 / 23447246
kidney13 / 21177761
larynx0 / 241450 
liver33 / 207743158
lung21 / 33697462
lymph0 / 442700 
lymph node4 / 9161043
mammary gland5 / 15327132
mouth3 / 6705244
muscle4 / 10771537
nerve0 / 157680 
ovary4 / 10205139
pancreas6 / 21481227
parathyroid3 / 20539146
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta6 / 28082521
prostate14 / 18934573
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach8 / 9661982
testis3 / 3304429
thymus1 / 8113112
thyroid4 / 4747384
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203815_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.95
Adipocyte42.6
AdrenalCortex8.45
Adrenalgland58.45
Amygdala14.65
Appendix9.2
AtrioventricularNode8.05
BDCA4+_DentriticCells6.2
Bonemarrow9.55
BronchialEpithelialCells5.6
CD105+_Endothelial85.2
CD14+_Monocytes8
CD19+_BCells(neg._sel.)7.45
CD33+_Myeloid9.9
CD34+15.65
CD4+_Tcells8.85
CD56+_NKCells7.15
CD71+_EarlyErythroid7.95
CD8+_Tcells5.35
CardiacMyocytes8.7
Caudatenucleus14.75
Cerebellum8.55
CerebellumPeduncles19.9
CiliaryGanglion7.6
CingulateCortex21.15
Colorectaladenocarcinoma43.1
DorsalRootGanglion8.2
FetalThyroid59.05
Fetalbrain10.75
Fetalliver10.55
Fetallung9.2
GlobusPallidus9.7
Heart84.15
Hypothalamus36.3
Kidney55.95
Leukemia_chronicMyelogenousK-56211.5
Leukemia_promyelocytic-HL-605.3
Leukemialymphoblastic(MOLT-4)4.8
Liver9.25
Lung127.7
Lymphnode12.55
Lymphoma_burkitts(Daudi)10.5
Lymphoma_burkitts(Raji)9.4
MedullaOblongata17.65
OccipitalLobe7.6
OlfactoryBulb15.2
Ovary7.15
Pancreas12.5
PancreaticIslet17.15
ParietalLobe10.75
Pituitary10.65
Placenta11.15
Pons22.65
PrefrontalCortex33.75
Prostate179.75
Salivarygland6.85
SkeletalMuscle14
Skin7.75
SmoothMuscle35.25
Spinalcord24.6
SubthalamicNucleus14.55
SuperiorCervicalGanglion10.65
TemporalLobe21.05
Testis7.95
TestisGermCell9.55
TestisIntersitial5.5
TestisLeydigCell8.15
TestisSeminiferousTubule7.95
Thalamus23.6
Thymus9.05
Thyroid173.8
Tongue10
Tonsil8.85
Trachea12.2
TrigeminalGanglion8.75
Uterus32.8
UterusCorpus9.6
WholeBlood6.2
Wholebrain4.9
colon83.95
pineal_day12.12
pineal_night15.48
retina71.95
small_intestine94.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P319001
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.43 ± 0.23
Basal Forebrain6.57 ± 0.27
Basal Part of Pons7.21 ± 0.25
Cerebellar Cortex6.9 ± 0.31
Cerebellar Nuclei7.43 ± 0.32
Claustrum6.04 ± 0.55
Epithalamus6.56 ± 0.26
Frontal Lobe6.76 ± 0.51
Globus Pallidus6.9 ± 0.17
Hypothalamus6.92 ± 0.33
Insula6.56 ± 0.42
Limbic Lobe6.31 ± 0.41
Mesencephalon6.72 ± 0.51
Myelencephalon6.62 ± 0.43
Occipital Lobe6.63 ± 0.29
Parietal Lobe6.83 ± 0.36
Pontine Tegmentum6.65 ± 0.34
Striatum6.24 ± 0.31
Subthalamus7.32 ± 0.08
Temporal Lobe6.55 ± 0.38
Thalamus6.79 ± 0.39
White Matter6.09 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gstt1CBCerebellum0.39
0.51
Gstt1CTXCerebral cortex0.58
0.48
Gstt1HIPHippocampal region0.33
0.35
Gstt1HPFHippocampal formation0.48
0.41
Gstt1HYHypothalamus1.09
1
Gstt1LSXLateral septal complex0.03
0
Gstt1MBMidbrain0.62
0.92
Gstt1MYMedulla1.57
1.51
Gstt1OLFOlfactory bulb4.06
2.74
Gstt1PPons2.09
2.44
Gstt1PALPallidum1.13
0.79
Gstt1RHPRetrohippocampal region0.58
0.31
Gstt1sAMYStriatum-like amygdalar nuclei1.35
0.98
Gstt1STRStriatum1.26
0.89
Gstt1STRdStriatum dorsal region0.26
0.2
Gstt1STRvStriatum ventral region5.22
3.33
Gstt1THThalamus0.21
0.14
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GSTT1_HUMAN_0 0 0 0 VEAAVGEDLFQEAHEVILK PRIDE
GSTT1_HUMAN_230 10 230 239 LMPWVLAMIR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018