Annotation Detail for GTF3C1
Basic Information Top
| Gene Symbol: | GTF3C1 ( DKFZp686A111,TFIIIC,TFIIIC220,TFIIICalpha ) |
|---|---|
| Gene Full Name: | general transcription factor IIIC, polypeptide 1, alpha 220kDa |
| Band: | 16p12.1 |
| Quick Links | Entrez ID:2975; OMIM: 603246; Uniprot ID:TF3C1_HUMAN; ENSEMBL ID: ENSG00000077235; HGNC ID: 4664 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.371718
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 7 / 70761 | 98 |  |
| blastocyst | 15 / 62319 | 240 |  |
| fetus | 21 / 564012 | 37 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 8 / 55556 | 143 | |
| adult | 127 / 1939121 | 65 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 6 / 94178 | 63 | |
| cervical tumor | 5 / 34366 | 145 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 21 / 114246 | 183 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 9 / 119369 | 75 | |
| germ cell tumor | 33 / 263845 | 125 | |
| glioma | 8 / 106883 | 74 | |
| head and neck tumor | 19 / 136302 | 139 | |
| kidney tumor | 8 / 68959 | 116 | |
| leukemia | 4 / 95842 | 41 | |
| liver tumor | 13 / 96359 | 134 | |
| lung tumor | 24 / 103127 | 232 | |
| lymphoma | 14 / 71755 | 195 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 196 / 3360307 | 58 | |
| ovarian tumor | 4 / 76682 | 52 | |
| pancreatic tumor | 12 / 104616 | 114 | |
| primitive neuroectodermal tumor of the CNS | 17 / 125680 | 135 | |
| prostate cancer | 9 / 102680 | 87 | |
| retinoblastoma | 7 / 46356 | 151 | |
| skin tumor | 17 / 124949 | 136 | |
| soft tissue/muscle tissue tumor | 5 / 125191 | 39 | |
| uterine tumor | 8 / 90257 | 88 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 7 / 123478 | 56 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 6 / 48801 | 122 | |
| brain | 71 / 1100989 | 64 | |
| cervix | 5 / 48171 | 103 | |
| connective tissue | 4 / 149255 | 26 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 27 / 215722 | 125 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 24 / 211054 | 113 | |
| heart | 0 / 89626 | 0 | |
| intestine | 29 / 234472 | 123 | |
| kidney | 12 / 211777 | 56 | |
| larynx | 3 / 24145 | 124 | |
| liver | 15 / 207743 | 72 | |
| lung | 34 / 336974 | 100 | |
| lymph | 10 / 44270 | 225 | |
| lymph node | 7 / 91610 | 76 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 9 / 67052 | 134 | |
| muscle | 13 / 107715 | 120 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 13 / 102051 | 127 | |
| pancreas | 17 / 214812 | 79 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 2 / 16585 | 120 | |
| placenta | 16 / 280825 | 56 | |
| prostate | 16 / 189345 | 84 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 23 / 210574 | 109 | |
| spleen | 5 / 53952 | 92 | |
| stomach | 3 / 96619 | 31 | |
| testis | 23 / 330442 | 69 | |
| thymus | 12 / 81131 | 147 | |
| thyroid | 12 / 47473 | 252 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 21 / 232878 | 90 | |
| vascular | 2 / 51780 | 38 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 35671_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 141.8 | |
| Adipocyte | 27.2 | |
| AdrenalCortex | 43.25 | |
| Adrenalgland | 32.75 | |
| Amygdala | 60.35 | |
| Appendix | 19.1 | |
| AtrioventricularNode | 18.2 | |
| BDCA4+_DentriticCells | 150.05 | |
| Bonemarrow | 36.85 | |
| BronchialEpithelialCells | 72.55 | |
| CD105+_Endothelial | 56.8 | |
| CD14+_Monocytes | 69.7 | |
| CD19+_BCells(neg._sel.) | 44.55 | |
| CD33+_Myeloid | 98.45 | |
| CD34+ | 127 | |
| CD4+_Tcells | 133.15 | |
| CD56+_NKCells | 583.35 | |
| CD71+_EarlyErythroid | 33.7 | |
| CD8+_Tcells | 221.05 | |
| CardiacMyocytes | 30.6 | |
| Caudatenucleus | 34.8 | |
| Cerebellum | 42.45 | |
| CerebellumPeduncles | 48.05 | |
| CiliaryGanglion | 17.45 | |
| CingulateCortex | 52.7 | |
| Colorectaladenocarcinoma | 37.15 | |
| DorsalRootGanglion | 17.15 | |
| FetalThyroid | 73.15 | |
| Fetalbrain | 52.8 | |
| Fetalliver | 26.25 | |
| Fetallung | 71.7 | |
| GlobusPallidus | 22.95 | |
| Heart | 83.45 | |
| Hypothalamus | 47.55 | |
| Kidney | 25.35 | |
| Leukemia_chronicMyelogenousK-562 | 57.65 | |
| Leukemia_promyelocytic-HL-60 | 25.5 | |
| Leukemialymphoblastic(MOLT-4) | 58.7 | |
| Liver | 67.75 | |
| Lung | 119.4 | |
| Lymphnode | 29.5 | |
| Lymphoma_burkitts(Daudi) | 38.75 | |
| Lymphoma_burkitts(Raji) | 93.25 | |
| MedullaOblongata | 39.45 | |
| OccipitalLobe | 37.5 | |
| OlfactoryBulb | 32.95 | |
| Ovary | 9.7 |  |
| Pancreas | 37.3 | |
| PancreaticIslet | 39 | |
| ParietalLobe | 40.15 | |
| Pituitary | 86.85 | |
| Placenta | 33 | |
| Pons | 32.35 | |
| PrefrontalCortex | 184.15 | |
| Prostate | 444.45 | |
| Salivarygland | 11.25 | |
| SkeletalMuscle | 44 | |
| Skin | 24.5 | |
| SmoothMuscle | 34.95 | |
| Spinalcord | 52.7 | |
| SubthalamicNucleus | 48.3 | |
| SuperiorCervicalGanglion | 12.8 | |
| TemporalLobe | 38.9 | |
| Testis | 94.75 | |
| TestisGermCell | 45.1 | |
| TestisIntersitial | 35.05 | |
| TestisLeydigCell | 34.8 | |
| TestisSeminiferousTubule | 43.9 | |
| Thalamus | 38.3 | |
| Thymus | 89.15 | |
| Thyroid | 319.85 | |
| Tongue | 49.95 | |
| Tonsil | 35.5 | |
| Trachea | 21.35 | |
| TrigeminalGanglion | 24.25 | |
| Uterus | 52.1 | |
| UterusCorpus | 40.9 | |
| WholeBlood | 46.35 | |
| Wholebrain | 104.65 | |
| colon | 29.3 | |
| pineal_day | 197.82 | |
| pineal_night | 240.14 | |
| retina | 55.775 | |
| small_intestine | 28.8 | |
- Probe name: CUST_12903_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.06 ± 0.72 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.29 ± 0.42 | |
| Basal Part of Pons | 2.55 ± 0.46 | |
| Cerebellar Cortex | 2.84 ± 0.7 | |
| Cerebellar Nuclei | 2.6 ± 0.46 | |
| Claustrum | 3.2 ± 0.64 | |
| Epithalamus | 2.61 ± 0.7 | |
| Frontal Lobe | 2.64 ± 0.72 | |
| Globus Pallidus | 2.7 ± 0.81 | |
| Hypothalamus | 2.51 ± 0.39 | |
| Insula | 2.7 ± 0.55 | |
| Limbic Lobe | 2.87 ± 0.75 | |
| Mesencephalon | 2.98 ± 0.95 | |
| Myelencephalon | 2.76 ± 0.63 | |
| Occipital Lobe | 2.9 ± 0.75 | |
| Parietal Lobe | 2.87 ± 0.7 | |
| Pontine Tegmentum | 2.7 ± 0.51 | |
| Striatum | 2.64 ± 0.63 | |
| Subthalamus | 2.76 ± 0.59 | |
| Temporal Lobe | 2.9 ± 0.59 | |
| Thalamus | 2.59 ± 0.64 | |
| White Matter | 3.08 ± 0.32 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Gtf3c1 | CB | Cerebellum | 25.77 | |
| 48.82 | | |||
| Gtf3c1 | CTX | Cerebral cortex | 94.27 | |
| 81.28 | | |||
| Gtf3c1 | HIP | Hippocampal region | 66.86 | |
| 100 | | |||
| Gtf3c1 | HPF | Hippocampal formation | 75.86 | |
| 100 | | |||
| Gtf3c1 | HY | Hypothalamus | 50.14 | |
| 39.91 | | |||
| Gtf3c1 | LSX | Lateral septal complex | 70.02 | |
| 53.15 | | |||
| Gtf3c1 | MB | Midbrain | 55 | |
| 53.62 | | |||
| Gtf3c1 | MY | Medulla | 51.74 | |
| 61.65 | | |||
| Gtf3c1 | OLF | Olfactory bulb | 74.36 | |
| 73.49 | | |||
| Gtf3c1 | P | Pons | 49.36 | |
| 53.92 | | |||
| Gtf3c1 | PAL | Pallidum | 59.44 | |
| 56.11 | | |||
| Gtf3c1 | RHP | Retrohippocampal region | 95.21 | |
| 89.52 | | |||
| Gtf3c1 | sAMY | Striatum-like amygdalar nuclei | 81.08 | |
| 66 | | |||
| Gtf3c1 | STR | Striatum | 100 | |
| 82.03 | | |||
| Gtf3c1 | STRd | Striatum dorsal region | 100 | |
| 90.66 | | |||
| Gtf3c1 | STRv | Striatum ventral region | 100 | |
| 79.21 | | |||
| Gtf3c1 | TH | Thalamus | 64.57 | |
| 62.18 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00026679 | 24 | 1688 | 1711 | LRPAAAPLEELTMGTSCLPDTFTK | Peptide Atlas |