Annotation Detail for BLNK
Basic Information Top
| Gene Symbol: | BLNK ( AGM4,BASH,BLNK-S,LY57,MGC111051,SLP-65,SLP65 ) |
|---|---|
| Gene Full Name: | B-cell linker |
| Band: | 10q24.1 |
| Quick Links | Entrez ID:29760; OMIM: 604515; Uniprot ID:BLNK_HUMAN; ENSEMBL ID: ENSG00000095585; HGNC ID: 14211 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.665244
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 5 / 564012 | 8 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 |  |
| adult | 21 / 1939121 | 10 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 1 / 263845 | 3 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 8 / 71755 | 111 |  |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 44 / 3360307 | 13 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 3 / 123478 | 24 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 3 / 1100989 | 2 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 3 / 336974 | 8 | |
| lymph | 2 / 44270 | 45 | |
| lymph node | 8 / 91610 | 87 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 4 / 214812 | 18 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 8 / 41328 | 193 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 6 / 280825 | 21 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 2 / 96619 | 20 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 3 / 16999 | 176 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 3 / 232878 | 12 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 207655_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 1092.5 |  |
| Adipocyte | 7.3 | |
| AdrenalCortex | 8.5 | |
| Adrenalgland | 6.4 | |
| Amygdala | 7.85 | |
| Appendix | 9.9 | |
| AtrioventricularNode | 6.2 | |
| BDCA4+_DentriticCells | 1381.3 | |
| Bonemarrow | 8.4 | |
| BronchialEpithelialCells | 7.55 | |
| CD105+_Endothelial | 8.35 | |
| CD14+_Monocytes | 9.05 | |
| CD19+_BCells(neg._sel.) | 830.5 |  |
| CD33+_Myeloid | 10.05 | |
| CD34+ | 226.7 | |
| CD4+_Tcells | 7.35 | |
| CD56+_NKCells | 9.35 | |
| CD71+_EarlyErythroid | 7.05 | |
| CD8+_Tcells | 6.45 | |
| CardiacMyocytes | 10.75 | |
| Caudatenucleus | 6.75 | |
| Cerebellum | 6.2 | |
| CerebellumPeduncles | 8.8 | |
| CiliaryGanglion | 5.75 | |
| CingulateCortex | 7.7 | |
| Colorectaladenocarcinoma | 7.4 | |
| DorsalRootGanglion | 6.25 | |
| FetalThyroid | 8.1 | |
| Fetalbrain | 7.3 | |
| Fetalliver | 6.55 | |
| Fetallung | 6.3 | |
| GlobusPallidus | 5.65 | |
| Heart | 10.7 | |
| Hypothalamus | 8.55 | |
| Kidney | 8.4 | |
| Leukemia_chronicMyelogenousK-562 | 6.75 | |
| Leukemia_promyelocytic-HL-60 | 43.05 | |
| Leukemialymphoblastic(MOLT-4) | 5.9 | |
| Liver | 12.65 | |
| Lung | 8.3 | |
| Lymphnode | 171.35 | |
| Lymphoma_burkitts(Daudi) | 232.1 | |
| Lymphoma_burkitts(Raji) | 13.5 | |
| MedullaOblongata | 6.85 | |
| OccipitalLobe | 6.6 | |
| OlfactoryBulb | 6.05 | |
| Ovary | 5.55 | |
| Pancreas | 6.5 | |
| PancreaticIslet | 10.5 | |
| ParietalLobe | 8 | |
| Pituitary | 8.95 | |
| Placenta | 7.75 | |
| Pons | 7.3 | |
| PrefrontalCortex | 9.1 | |
| Prostate | 9 | |
| Salivarygland | 31.3 | |
| SkeletalMuscle | 9.2 | |
| Skin | 6.2 | |
| SmoothMuscle | 8.55 | |
| Spinalcord | 12.1 | |
| SubthalamicNucleus | 6.9 | |
| SuperiorCervicalGanglion | 13.35 | |
| TemporalLobe | 6.95 | |
| Testis | 6.5 | |
| TestisGermCell | 6.45 | |
| TestisIntersitial | 6.25 | |
| TestisLeydigCell | 7.6 | |
| TestisSeminiferousTubule | 6.4 | |
| Thalamus | 7.7 | |
| Thymus | 11 | |
| Thyroid | 15.15 | |
| Tongue | 9.35 | |
| Tonsil | 209.55 | |
| Trachea | 6.5 | |
| TrigeminalGanglion | 8.4 | |
| Uterus | 6.15 | |
| UterusCorpus | 7.05 | |
| WholeBlood | 9 | |
| Wholebrain | 6.4 | |
| colon | 30.4 | |
| pineal_day | 9.46 | |
| pineal_night | 8.86 | |
| retina | 9.25 | |
| small_intestine | 94.3 | |
- Probe name: CUST_9853_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.93 ± 0.74 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.68 ± 0.61 | |
| Basal Part of Pons | 3.94 ± 0.53 | |
| Cerebellar Cortex | 3.12 ± 0.46 | |
| Cerebellar Nuclei | 4.73 ± 0.57 | |
| Claustrum | 3.85 ± 0.68 | |
| Epithalamus | 4.26 ± 0.51 | |
| Frontal Lobe | 3.55 ± 0.67 | |
| Globus Pallidus | 5.13 ± 0.37 | |
| Hypothalamus | 3.5 ± 1.21 | |
| Insula | 3.69 ± 0.73 | |
| Limbic Lobe | 3.54 ± 0.62 | |
| Mesencephalon | 3.77 ± 0.84 | |
| Myelencephalon | 3.64 ± 0.7 | |
| Occipital Lobe | 3.41 ± 0.65 | |
| Parietal Lobe | 3.54 ± 0.68 | |
| Pontine Tegmentum | 3.62 ± 0.7 | |
| Striatum | 3.86 ± 0.48 | |
| Subthalamus | 4.07 ± 0.51 | |
| Temporal Lobe | 3.69 ± 0.71 | |
| Thalamus | 3.57 ± 0.55 | |
| White Matter | 4.76 ± 0.82 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Blnk | CB | Cerebellum | 17.57 | |
| 24.78 | | |||
| Blnk | CTX | Cerebral cortex | 33.62 | |
| 28.88 | | |||
| Blnk | HIP | Hippocampal region | 32.96 | |
| 51.01 | | |||
| Blnk | HPF | Hippocampal formation | 29.71 | |
| 39.59 | | |||
| Blnk | HY | Hypothalamus | 20 | |
| 19.43 | | |||
| Blnk | LSX | Lateral septal complex | 4.27 | |
| 3.63 | | |||
| Blnk | MB | Midbrain | 16.2 | |
| 17.92 | | |||
| Blnk | MY | Medulla | 10.9 | |
| 13.98 | | |||
| Blnk | OLF | Olfactory bulb | 24.99 | |
| 25.36 | | |||
| Blnk | P | Pons | 21.24 | |
| 24.08 | | |||
| Blnk | PAL | Pallidum | 5.23 | |
| 5.19 | | |||
| Blnk | RHP | Retrohippocampal region | 25.06 | |
| 26.39 | | |||
| Blnk | sAMY | Striatum-like amygdalar nuclei | 9.3 | |
| 8.5 | | |||
| Blnk | STR | Striatum | 7.13 | |
| 5.9 | | |||
| Blnk | STRd | Striatum dorsal region | 4.89 | |
| 3.95 | | |||
| Blnk | STRv | Striatum ventral region | 14.47 | |
| 11 | | |||
| Blnk | TH | Thalamus | 29.56 | |
| 30.07 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00031710 | 23 | 258 | 280 | TTPVASQQNASSVCEEKPIPAER | Peptide Atlas |