AutismKB 2.0

Annotation Detail for PACSIN3


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Basic Information Top
Gene Symbol:PACSIN3 ( FLJ17861,SDPIII )
Gene Full Name: protein kinase C and casein kinase substrate in neurons 3
Band: 11p11.2
Quick LinksEntrez ID:29763; OMIM: 606513; Uniprot ID:PACN3_HUMAN; ENSEMBL ID: ENSG00000165912; HGNC ID: 8572
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst6 / 6231996
fetus6 / 56401210
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor5 / 34366145
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor2 / 17290115
gastrointestinal tumor6 / 11936950
germ cell tumor8 / 26384530
glioma4 / 10688337
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal91 / 336030727
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer6 / 10268058
retinoblastoma3 / 4635664
skin tumor7 / 12494956
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites4 / 4001599
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain18 / 110098916
cervix10 / 48171207
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus2 / 2020998
eye10 / 21105447
heart2 / 8962622
intestine9 / 23447238
kidney4 / 21177718
larynx0 / 241450 
liver5 / 20774324
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland7 / 15327145
mouth0 / 670520 
muscle17 / 107715157
nerve0 / 157680 
ovary3 / 10205129
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta21 / 28082574
prostate8 / 18934542
salivary gland1 / 2015549
skin7 / 21057433
spleen0 / 539520 
stomach4 / 9661941
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218744_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.05
Adipocyte5.3
AdrenalCortex15.05
Adrenalgland7.5
Amygdala5.7
Appendix5.95
AtrioventricularNode4.7
BDCA4+_DentriticCells5.3
Bonemarrow5.35
BronchialEpithelialCells5.6
CD105+_Endothelial5.45
CD14+_Monocytes5.7
CD19+_BCells(neg._sel.)5.7
CD33+_Myeloid6.65
CD34+6.85
CD4+_Tcells5.55
CD56+_NKCells6.35
CD71+_EarlyErythroid5.1
CD8+_Tcells4.8
CardiacMyocytes6.8
Caudatenucleus4.9
Cerebellum4.4
CerebellumPeduncles6.35
CiliaryGanglion4
CingulateCortex5.6
Colorectaladenocarcinoma6.25
DorsalRootGanglion4.3
FetalThyroid10.55
Fetalbrain5.2
Fetalliver4.75
Fetallung4.5
GlobusPallidus4.1
Heart27.4
Hypothalamus5.95
Kidney4.7
Leukemia_chronicMyelogenousK-5624.9
Leukemia_promyelocytic-HL-604.8
Leukemialymphoblastic(MOLT-4)4.3
Liver11.75
Lung6.05
Lymphnode4.6
Lymphoma_burkitts(Daudi)6.95
Lymphoma_burkitts(Raji)7.7
MedullaOblongata8.1
OccipitalLobe4.95
OlfactoryBulb4.3
Ovary3.75
Pancreas5.1
PancreaticIslet5.85
ParietalLobe6
Pituitary6.35
Placenta6.3
Pons5.25
PrefrontalCortex6.65
Prostate8.05
Salivarygland10.15
SkeletalMuscle26.6
Skin4.4
SmoothMuscle6.2
Spinalcord8
SubthalamicNucleus5
SuperiorCervicalGanglion6.4
TemporalLobe5.05
Testis4.7
TestisGermCell4.45
TestisIntersitial4.4
TestisLeydigCell5.45
TestisSeminiferousTubule4.65
Thalamus5.55
Thymus4.1
Thyroid7.2
Tongue7.45
Tonsil5.3
Trachea4.55
TrigeminalGanglion5.75
Uterus4.45
UterusCorpus4.95
WholeBlood5.7
Wholebrain4.6
colon5.45
pineal_day6.84
pineal_night6.56
retina6.775
small_intestine5.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8947_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.35 ± 0.47
Basal Forebrain4.65 ± 0.59
Basal Part of Pons4.44 ± 0.69
Cerebellar Cortex4.44 ± 0.5
Cerebellar Nuclei4.81 ± 0.71
Claustrum4.95 ± 0.67
Epithalamus4.73 ± 0.39
Frontal Lobe4.22 ± 0.51
Globus Pallidus5.69 ± 0.33
Hypothalamus4.02 ± 0.61
Insula4.13 ± 0.46
Limbic Lobe4.45 ± 0.67
Mesencephalon4.63 ± 0.65
Myelencephalon4.53 ± 0.68
Occipital Lobe4.96 ± 0.8
Parietal Lobe4.46 ± 0.56
Pontine Tegmentum4.46 ± 0.64
Striatum4.68 ± 0.57
Subthalamus3.91 ± 0.46
Temporal Lobe4.23 ± 0.55
Thalamus4.47 ± 0.58
White Matter6.42 ± 0.57
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pacsin3CBCerebellum32
41.05
Pacsin3CTXCerebral cortex41.98
31.42
Pacsin3HIPHippocampal region1.68
1.45
Pacsin3HPFHippocampal formation2.61
2.16
Pacsin3HYHypothalamus1.61
1.29
Pacsin3LSXLateral septal complex1.33
1.07
Pacsin3MBMidbrain7.12
6.84
Pacsin3MYMedulla19.13
20.07
Pacsin3OLFOlfactory bulb31.44
41.52
Pacsin3PPons10.95
11.96
Pacsin3PALPallidum1.08
0.87
Pacsin3RHPRetrohippocampal region4.69
3.56
Pacsin3sAMYStriatum-like amygdalar nuclei0.69
0.51
Pacsin3STRStriatum1.47
1.4
Pacsin3STRdStriatum dorsal region1.8
1.8
Pacsin3STRvStriatum ventral region0.85
0.84
Pacsin3THThalamus20.82
17.31
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010682 12 35 46 LCGDLVSCFQER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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