AutismKB 2.0

Annotation Detail for CARD10


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Basic Information Top
Gene Symbol:CARD10 ( BIMP1,CARMA3,MGC142219 )
Gene Full Name: caspase recruitment domain family, member 10
Band: 22q13.1
Quick LinksEntrez ID:29775; OMIM: 607209; Uniprot ID:CAR10_HUMAN; ENSEMBL ID: ENSG00000100065; HGNC ID: 16422
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor7 / 68959101
leukemia2 / 9584220
liver tumor6 / 9635962
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal68 / 336030720
ovarian tumor0 / 766820 
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain9 / 11009898
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye4 / 21105418
heart3 / 8962633
intestine9 / 23447238
kidney25 / 211777118
larynx0 / 241450 
liver7 / 20774333
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve1 / 1576863
ovary1 / 1020519
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate3 / 18934515
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis25 / 33044275
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210025_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5
Adipocyte4.65
AdrenalCortex4.95
Adrenalgland7
Amygdala4.6
Appendix4.75
AtrioventricularNode3.85
BDCA4+_DentriticCells4.4
Bonemarrow7.2
BronchialEpithelialCells4.2
CD105+_Endothelial4.25
CD14+_Monocytes4.85
CD19+_BCells(neg._sel.)3.9
CD33+_Myeloid5.4
CD34+5.15
CD4+_Tcells4.75
CD56+_NKCells5.45
CD71+_EarlyErythroid6.15
CD8+_Tcells4.25
CardiacMyocytes5.4
Caudatenucleus6.3
Cerebellum6.75
CerebellumPeduncles5.4
CiliaryGanglion4.9
CingulateCortex8.55
Colorectaladenocarcinoma4.25
DorsalRootGanglion4.75
FetalThyroid4.45
Fetalbrain5.1
Fetalliver4.5
Fetallung3.55
GlobusPallidus15.9
Heart5.85
Hypothalamus4.25
Kidney7
Leukemia_chronicMyelogenousK-5625.8
Leukemia_promyelocytic-HL-604.15
Leukemialymphoblastic(MOLT-4)4.2
Liver6.5
Lung4.3
Lymphnode5.9
Lymphoma_burkitts(Daudi)7
Lymphoma_burkitts(Raji)6.5
MedullaOblongata7
OccipitalLobe4.25
OlfactoryBulb4.8
Ovary3.1
Pancreas3.75
PancreaticIslet5.5
ParietalLobe4.95
Pituitary8.75
Placenta4.35
Pons7.8
PrefrontalCortex4.6
Prostate4.4
Salivarygland5.45
SkeletalMuscle7.85
Skin4.9
SmoothMuscle4.7
Spinalcord8.65
SubthalamicNucleus9.95
SuperiorCervicalGanglion5.5
TemporalLobe7.05
Testis5.05
TestisGermCell3.35
TestisIntersitial3.9
TestisLeydigCell4.6
TestisSeminiferousTubule4.85
Thalamus11
Thymus3.55
Thyroid4.55
Tongue6.75
Tonsil4.55
Trachea6.65
TrigeminalGanglion7.55
Uterus3.3
UterusCorpus3.85
WholeBlood4.25
Wholebrain3.7
colon3.85
pineal_day5.1
pineal_night4.58
retina5.3
small_intestine3.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16230_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.59 ± 1.01
Basal Forebrain2.25 ± 0.57
Basal Part of Pons1.9 ± 0.37
Cerebellar Cortex2.13 ± 0.84
Cerebellar Nuclei2.54 ± 0.71
Claustrum3.09 ± 0.89
Epithalamus1.95 ± 0.75
Frontal Lobe2.08 ± 0.71
Globus Pallidus2.73 ± 0.33
Hypothalamus2.29 ± 0.52
Insula2.01 ± 0.4
Limbic Lobe2.18 ± 0.65
Mesencephalon2.43 ± 0.64
Myelencephalon2.25 ± 0.6
Occipital Lobe2.26 ± 0.7
Parietal Lobe2.21 ± 0.67
Pontine Tegmentum2.25 ± 0.79
Striatum2.29 ± 0.49
Subthalamus2.4 ± 0.74
Temporal Lobe2.18 ± 0.67
Thalamus2.19 ± 0.59
White Matter2.54 ± 0.14
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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