AutismKB 2.0

Annotation Detail for PARVB


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Basic Information Top
Gene Symbol:PARVB ( CGI-56 )
Gene Full Name: parvin, beta
Band: 22q13.31
Quick LinksEntrez ID:29780; OMIM: 608121; Uniprot ID:PARVB_HUMAN; ENSEMBL ID: ENSG00000188677; HGNC ID: 14653
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus26 / 56401246
neonate5 / 31097160
infant0 / 236200 
juvenile1 / 5555617
adult90 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal143 / 336030742
ovarian tumor2 / 7668226
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS23 / 125680183
prostate cancer7 / 10268068
retinoblastoma0 / 463560 
skin tumor12 / 12494996
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood5 / 12347840
bone2 / 7165527
bone marrow2 / 4880140
brain14 / 110098912
cervix8 / 48171166
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye14 / 21105466
heart2 / 8962622
intestine9 / 23447238
kidney6 / 21177728
larynx0 / 241450 
liver4 / 20774319
lung7 / 33697420
lymph1 / 4427022
lymph node0 / 916100 
mammary gland4 / 15327126
mouth1 / 6705214
muscle4 / 10771537
nerve2 / 15768126
ovary2 / 10205119
pancreas38 / 214812176
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta20 / 28082571
prostate11 / 18934558
salivary gland0 / 201550 
skin15 / 21057471
spleen5 / 5395292
stomach3 / 9661931
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord5 / 13680365
uterus4 / 23287817
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 37965_at
Cell line Expression level Expression bar
721_B_lymphoblasts176.45
Adipocyte10.1
AdrenalCortex6.2
Adrenalgland4.85
Amygdala6.7
Appendix5.9
AtrioventricularNode4.65
BDCA4+_DentriticCells40.15
Bonemarrow10.7
BronchialEpithelialCells5.7
CD105+_Endothelial57.15
CD14+_Monocytes29.7
CD19+_BCells(neg._sel.)38.5
CD33+_Myeloid18.05
CD34+18.4
CD4+_Tcells5.55
CD56+_NKCells6.55
CD71+_EarlyErythroid105.1
CD8+_Tcells4.65
CardiacMyocytes12.7
Caudatenucleus5
Cerebellum4.5
CerebellumPeduncles6.25
CiliaryGanglion3.7
CingulateCortex5.7
Colorectaladenocarcinoma28.35
DorsalRootGanglion4.5
FetalThyroid5.4
Fetalbrain5
Fetalliver5.25
Fetallung6.55
GlobusPallidus4.2
Heart52.6
Hypothalamus5.7
Kidney4.75
Leukemia_chronicMyelogenousK-5628.6
Leukemia_promyelocytic-HL-6010
Leukemialymphoblastic(MOLT-4)3.4
Liver7.65
Lung20.3
Lymphnode6.05
Lymphoma_burkitts(Daudi)6.7
Lymphoma_burkitts(Raji)21
MedullaOblongata4.95
OccipitalLobe5
OlfactoryBulb4.5
Ovary4
Pancreas4.4
PancreaticIslet11.45
ParietalLobe5.95
Pituitary6.5
Placenta7.55
Pons5.35
PrefrontalCortex6.9
Prostate6.6
Salivarygland4.45
SkeletalMuscle8.85
Skin4.3
SmoothMuscle8.05
Spinalcord6.55
SubthalamicNucleus5.75
SuperiorCervicalGanglion6.75
TemporalLobe5.2
Testis4.75
TestisGermCell4.15
TestisIntersitial4.7
TestisLeydigCell4.65
TestisSeminiferousTubule4.45
Thalamus5.85
Thymus4.45
Thyroid9.65
Tongue5.75
Tonsil5.45
Trachea4.6
TrigeminalGanglion5.85
Uterus5.95
UterusCorpus4.8
WholeBlood32.6
Wholebrain5.8
colon5.55
pineal_day8.76
pineal_night7.72
retina11.35
small_intestine5.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6383_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.39 ± 0.54
Basal Forebrain4.64 ± 0.32
Basal Part of Pons4.57 ± 0.68
Cerebellar Cortex4.29 ± 0.5
Cerebellar Nuclei4.9 ± 0.46
Claustrum4 ± 0.8
Epithalamus4.02 ± 0.69
Frontal Lobe4.68 ± 0.45
Globus Pallidus4.43 ± 0.72
Hypothalamus4.91 ± 0.44
Insula4.84 ± 0.48
Limbic Lobe4.56 ± 0.58
Mesencephalon4.68 ± 0.52
Myelencephalon4.62 ± 0.59
Occipital Lobe4.34 ± 0.61
Parietal Lobe4.64 ± 0.47
Pontine Tegmentum4.72 ± 0.6
Striatum4.36 ± 0.65
Subthalamus4.75 ± 0.28
Temporal Lobe4.94 ± 0.44
Thalamus4.88 ± 0.63
White Matter3.53 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
ParvbCBCerebellum3.86
5.63
ParvbCTXCerebral cortex3.52
3.7
ParvbHIPHippocampal region6.28
7.09
ParvbHPFHippocampal formation4.84
5.39
ParvbHYHypothalamus3.17
3.77
ParvbLSXLateral septal complex3.62
4.3
ParvbMBMidbrain3.84
4.98
ParvbMYMedulla7.38
8.68
ParvbOLFOlfactory bulb5.29
5.6
ParvbPPons3.43
4.15
ParvbPALPallidum5.42
6.6
ParvbRHPRetrohippocampal region2.62
3.05
ParvbsAMYStriatum-like amygdalar nuclei3.7
4.16
ParvbSTRStriatum4.07
4.49
ParvbSTRdStriatum dorsal region4.28
4.69
ParvbSTRvStriatum ventral region3.76
3.35
ParvbTHThalamus7.56
7.89
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PARVB_HUMAN_109 14 109 122 QLEEDLYDGQVLQK PRIDE
PARVB_HUMAN_132 14 132 145 LNVAEVTQSEIGQK PRIDE
PARVB_HUMAN_146 17 146 162 QKLQTVLEAVHDLLRPR PRIDE
PARVB_HUMAN_148 15 148 162 LQTVLEAVHDLLRPR PRIDE
PARVB_HUMAN_194 17 194 210 APIRLPEHVTVQVVVVR PRIDE
PARVB_HUMAN_198 13 198 210 LPEHVTVQVVVVR PRIDE
PARVB_HUMAN_213 23 213 235 EGLLHSSHISEELTTTTEMMMGR PRIDE
PARVB_HUMAN_239 18 239 256 DAFDTLFDHAPDKLSVVK PRIDE
PARVB_HUMAN_239 19 239 257 DAFDTLFDHAPDKLSVVKK PRIDE
PARVB_HUMAN_258 8 258 265 SLITFVNK PRIDE
PARVB_HUMAN_335 12 335 346 ARPEDVVNLDLK PRIDE
PARVB_HUMAN_351 8 351 358 VLYNLFTK PRIDE
PARVB_HUMAN_91 14 91 104 VLLDWINDVLVEER PRIDE
PAp00064029 12 336 347 ARPEDVVNLDLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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