AutismKB 2.0

Annotation Detail for OLA1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:OLA1 ( DKFZp313H1942,DOC45,GBP45,GTPBP9 )
Gene Full Name: Obg-like ATPase 1
Band: 2q31.1
Quick LinksEntrez ID:29789; OMIM: 611175; Uniprot ID:OLA1_HUMAN; ENSEMBL ID: ENSG00000138430; HGNC ID: 28833
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst5 / 6231980
fetus65 / 564012115
neonate0 / 310970 
infant7 / 23620296
juvenile4 / 5555671
adult243 / 1939121125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma7 / 17475400
breast (mammary gland) tumor29 / 94178307
cervical tumor7 / 34366203
chondrosarcoma9 / 82823108
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor21 / 119369175
germ cell tumor38 / 263845144
glioma14 / 106883130
head and neck tumor14 / 136302102
kidney tumor10 / 68959145
leukemia24 / 95842250
liver tumor24 / 96359249
lung tumor9 / 10312787
lymphoma1 / 7175513
non-neoplasia8 / 9725082
normal335 / 336030799
ovarian tumor14 / 76682182
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS26 / 125680206
prostate cancer13 / 102680126
retinoblastoma13 / 46356280
skin tumor16 / 124949128
soft tissue/muscle tissue tumor40 / 125191319
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites8 / 40015199
bladder12 / 29757403
blood12 / 12347897
bone11 / 71655153
bone marrow17 / 48801348
brain179 / 1100989162
cervix7 / 48171145
connective tissue37 / 149255247
ear0 / 162120 
embryonic tissue38 / 215722176
esophagus0 / 202090 
eye22 / 211054104
heart6 / 8962666
intestine17 / 23447272
kidney20 / 21177794
larynx1 / 2414541
liver28 / 207743134
lung23 / 33697468
lymph1 / 4427022
lymph node14 / 91610152
mammary gland32 / 153271208
mouth10 / 67052149
muscle7 / 10771564
nerve1 / 1576863
ovary15 / 102051146
pancreas15 / 21481269
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland3 / 16585180
placenta32 / 280825113
prostate15 / 18934579
salivary gland3 / 20155148
skin23 / 210574109
spleen1 / 5395218
stomach15 / 96619155
testis65 / 330442196
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus26 / 232878111
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219293_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1953.95
Adipocyte230.15
AdrenalCortex150.9
Adrenalgland137.9
Amygdala836.95
Appendix118.45
AtrioventricularNode94.95
BDCA4+_DentriticCells591.1
Bonemarrow96.4
BronchialEpithelialCells1443.65
CD105+_Endothelial1220.65
CD14+_Monocytes747.3
CD19+_BCells(neg._sel.)680.5
CD33+_Myeloid761.8
CD34+1643.5
CD4+_Tcells303.6
CD56+_NKCells750.65
CD71+_EarlyErythroid446.05
CD8+_Tcells314.5
CardiacMyocytes329.5
Caudatenucleus354.05
Cerebellum233.3
CerebellumPeduncles294.75
CiliaryGanglion117.45
CingulateCortex525.9
Colorectaladenocarcinoma718.3
DorsalRootGanglion109.35
FetalThyroid379.5
Fetalbrain921.65
Fetalliver186.15
Fetallung300.35
GlobusPallidus330.85
Heart28.55
Hypothalamus683.6
Kidney83.65
Leukemia_chronicMyelogenousK-5621218.05
Leukemia_promyelocytic-HL-601307.9
Leukemialymphoblastic(MOLT-4)1024.25
Liver131.75
Lung68.2
Lymphnode241.75
Lymphoma_burkitts(Daudi)999.6
Lymphoma_burkitts(Raji)1086.65
MedullaOblongata402.25
OccipitalLobe447.1
OlfactoryBulb185.9
Ovary111.75
Pancreas705.15
PancreaticIslet626.25
ParietalLobe341.65
Pituitary328.85
Placenta130.6
Pons203.15
PrefrontalCortex1076.2
Prostate305.25
Salivarygland309.35
SkeletalMuscle144.6
Skin116.95
SmoothMuscle544.5
Spinalcord413.55
SubthalamicNucleus523.4
SuperiorCervicalGanglion67.9
TemporalLobe310.8
Testis223.15
TestisGermCell325.95
TestisIntersitial291.95
TestisLeydigCell273.4
TestisSeminiferousTubule260.75
Thalamus461.85
Thymus173.65
Thyroid638.5
Tongue272.8
Tonsil299.7
Trachea168.9
TrigeminalGanglion59.45
Uterus206.9
UterusCorpus53.7
WholeBlood380.85
Wholebrain468.5
colon588.7
pineal_day595.06
pineal_night595.72
retina291.75
small_intestine392.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P28420
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.8 ± 0.23
Basal Forebrain10.39 ± 0.15
Basal Part of Pons10.77 ± 0.22
Cerebellar Cortex10.28 ± 0.22
Cerebellar Nuclei10.43 ± 0.35
Claustrum10.97 ± 0.42
Epithalamus9.87 ± 0.39
Frontal Lobe10.48 ± 0.32
Globus Pallidus10.12 ± 0.3
Hypothalamus10.4 ± 0.25
Insula10.39 ± 0.24
Limbic Lobe10.78 ± 0.32
Mesencephalon10.43 ± 0.33
Myelencephalon10.5 ± 0.34
Occipital Lobe10.67 ± 0.28
Parietal Lobe10.58 ± 0.33
Pontine Tegmentum10.51 ± 0.29
Striatum10.77 ± 0.23
Subthalamus10.44 ± 0.19
Temporal Lobe10.58 ± 0.27
Thalamus10.55 ± 0.25
White Matter9.74 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gtpbp9CBCerebellum36.58
90.29
Gtpbp9CTXCerebral cortex100
100
Gtpbp9HIPHippocampal region100
100
Gtpbp9HPFHippocampal formation100
100
Gtpbp9HYHypothalamus68.67
72.65
Gtpbp9LSXLateral septal complex100
100
Gtpbp9MBMidbrain84.72
96.15
Gtpbp9MYMedulla87.23
100
Gtpbp9OLFOlfactory bulb100
100
Gtpbp9PPons75.04
100
Gtpbp9PALPallidum80.54
95.72
Gtpbp9RHPRetrohippocampal region100
100
Gtpbp9sAMYStriatum-like amygdalar nuclei98.08
100
Gtpbp9STRStriatum100
100
Gtpbp9STRdStriatum dorsal region100
100
Gtpbp9STRvStriatum ventral region100
100
Gtpbp9THThalamus81.71
87.63
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
OLA1_HUMAN_0 0 0 0 IPAFLNVVDIAGLVK PRIDE
OLA1_HUMAN_0 0 0 0 YEDFKEEGSENAVK PRIDE
OLA1_HUMAN_216 18 216 233 HLFLTSKPMVYLVNLSEK PRIDE
OLA1_HUMAN_216 22 216 237 HLFLTSKPMVYLVNLSEKDYIR PRIDE
OLA1_HUMAN_24 11 24 34 IGIVGLPNVGK PRIDE
OLA1_HUMAN_281 13 281 293 YLEANMTQSALPK PRIDE
OLA1_HUMAN_373 13 373 385 NYIVEDGDIIFFK PRIDE
OLA1_HUMAN_4 14 4 17 KGGDGIKPPPIIGR PRIDE
OLA1_HUMAN_83 15 83 97 IPAFLNVVDIAGLVK PRIDE
OLA1_HUMAN_84 15 84 98 IPAFLNVVDIAGLVK PRIDE
OLA1_HUMAN_98 27 98 124 GAHNGQGLGNAFLSHISACDGIFHLTR PRIDE
PAp00002359 13 71 83 FDFLCQYHKPASK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved