AutismKB 2.0

Annotation Detail for YPEL1


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Basic Information Top
Gene Symbol:YPEL1 ( MGC64992 )
Gene Full Name: yippee-like 1 (Drosophila)
Band: 22q11.21-q11.22
Quick LinksEntrez ID:29799; OMIM: 608082; Uniprot ID:YPEL1_HUMAN; ENSEMBL ID: ENSG00000100027; HGNC ID: 12845
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus32 / 56401256
neonate2 / 3109764
infant3 / 23620127
juvenile2 / 5555635
adult27 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor14 / 26384553
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal116 / 336030734
ovarian tumor3 / 7668239
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain47 / 110098942
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver2 / 2077439
lung6 / 33697417
lymph2 / 4427045
lymph node3 / 9161032
mammary gland1 / 1532716
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary3 / 10205129
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen2 / 5395237
stomach0 / 966190 
testis17 / 33044251
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord2 / 13680146
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213996_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.8
Adipocyte3.8
AdrenalCortex3.95
Adrenalgland3.2
Amygdala4.85
Appendix3.85
AtrioventricularNode2.85
BDCA4+_DentriticCells27.35
Bonemarrow3.75
BronchialEpithelialCells3.8
CD105+_Endothelial3.9
CD14+_Monocytes4.1
CD19+_BCells(neg._sel.)14.7
CD33+_Myeloid5.05
CD34+9.6
CD4+_Tcells4.3
CD56+_NKCells91
CD71+_EarlyErythroid3.55
CD8+_Tcells6.6
CardiacMyocytes5.25
Caudatenucleus5.1
Cerebellum3.15
CerebellumPeduncles4.4
CiliaryGanglion2.6
CingulateCortex3.95
Colorectaladenocarcinoma3.9
DorsalRootGanglion2.85
FetalThyroid3.75
Fetalbrain62.1
Fetalliver3.3
Fetallung3.25
GlobusPallidus2.75
Heart5
Hypothalamus4.3
Kidney3.05
Leukemia_chronicMyelogenousK-5623.5
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)24.65
Liver5.1
Lung4.65
Lymphnode3.35
Lymphoma_burkitts(Daudi)4.95
Lymphoma_burkitts(Raji)5.4
MedullaOblongata3.65
OccipitalLobe4.1
OlfactoryBulb3.05
Ovary2.55
Pancreas3.1
PancreaticIslet4.1
ParietalLobe4.1
Pituitary4.5
Placenta4
Pons5.1
PrefrontalCortex4.8
Prostate4.6
Salivarygland3.05
SkeletalMuscle4.5
Skin2.85
SmoothMuscle4.4
Spinalcord4.15
SubthalamicNucleus3.45
SuperiorCervicalGanglion4.4
TemporalLobe3.55
Testis210.15
TestisGermCell123.5
TestisIntersitial375.85
TestisLeydigCell310
TestisSeminiferousTubule128.4
Thalamus3.9
Thymus6
Thyroid4.8
Tongue3.8
Tonsil3.75
Trachea3.2
TrigeminalGanglion3.75
Uterus3.15
UterusCorpus3.65
WholeBlood4.25
Wholebrain9
colon3.9
pineal_day4.84
pineal_night4.72
retina4.725
small_intestine3.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P40548
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.66 ± 0.47
Basal Forebrain7.38 ± 0.54
Basal Part of Pons6.82 ± 0.32
Cerebellar Cortex6.56 ± 0.16
Cerebellar Nuclei6.05 ± 0.59
Claustrum6.51 ± 0.91
Epithalamus7.21 ± 0.25
Frontal Lobe7.13 ± 0.59
Globus Pallidus7.21 ± 0.44
Hypothalamus7.47 ± 0.3
Insula7.6 ± 0.19
Limbic Lobe7.35 ± 0.5
Mesencephalon7.03 ± 0.52
Myelencephalon7.05 ± 0.58
Occipital Lobe6.39 ± 0.66
Parietal Lobe6.89 ± 0.52
Pontine Tegmentum7.15 ± 0.61
Striatum8.26 ± 0.36
Subthalamus6.3 ± 0.87
Temporal Lobe7.47 ± 0.46
Thalamus6.57 ± 0.38
White Matter6.27 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ypel1CBCerebellum1.31
2.12
Ypel1CTXCerebral cortex3.29
2.54
Ypel1HIPHippocampal region2.96
3.26
Ypel1HPFHippocampal formation3.63
3.39
Ypel1HYHypothalamus0.23
0.26
Ypel1LSXLateral septal complex0.36
0.29
Ypel1MBMidbrain0.48
0.56
Ypel1MYMedulla0.59
0.71
Ypel1OLFOlfactory bulb4.26
3.07
Ypel1PPons0.46
0.6
Ypel1PALPallidum0.23
0.28
Ypel1RHPRetrohippocampal region5.19
3.92
Ypel1sAMYStriatum-like amygdalar nuclei0.91
0.68
Ypel1STRStriatum0.64
0.76
Ypel1STRdStriatum dorsal region0.63
0.91
Ypel1STRvStriatum ventral region0.44
0.41
Ypel1THThalamus0.77
0.77
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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