AutismKB 2.0

Annotation Detail for ZDHHC8


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZDHHC8 ( DHHC8,ZDHHCL1,ZNF378 )
Gene Full Name: zinc finger, DHHC-type containing 8
Band: 22q11.21
Quick LinksEntrez ID:29801; OMIM: 608784; Uniprot ID:ZDHC8_HUMAN; ENSEMBL ID: ENSG00000099904; HGNC ID: 18474
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma13 / 82823156
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor15 / 26384556
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor4 / 6895958
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal68 / 336030720
ovarian tumor9 / 76682117
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood4 / 12347832
bone6 / 7165583
bone marrow0 / 488010 
brain19 / 110098917
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine6 / 23447225
kidney8 / 21177737
larynx2 / 2414582
liver0 / 2077430 
lung16 / 33697447
lymph0 / 442700 
lymph node3 / 9161032
mammary gland4 / 15327126
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary18 / 102051176
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate4 / 18934521
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach3 / 9661931
testis1 / 3304423
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11219_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.9 ± 1.02
Basal Forebrain2.41 ± 0.35
Basal Part of Pons2.03 ± 0.45
Cerebellar Cortex2.32 ± 0.85
Cerebellar Nuclei2.82 ± 0.75
Claustrum3.1 ± 0.74
Epithalamus2.09 ± 1.15
Frontal Lobe2.27 ± 0.74
Globus Pallidus2.86 ± 0.59
Hypothalamus2.28 ± 0.63
Insula2.34 ± 0.76
Limbic Lobe2.64 ± 0.74
Mesencephalon2.63 ± 0.75
Myelencephalon2.47 ± 0.72
Occipital Lobe2.86 ± 0.71
Parietal Lobe2.45 ± 0.74
Pontine Tegmentum2.62 ± 0.78
Striatum2.68 ± 0.71
Subthalamus2.58 ± 0.65
Temporal Lobe2.54 ± 0.84
Thalamus2.39 ± 0.71
White Matter2.23 ± 0.52
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018