AutismKB 2.0

Annotation Detail for STRN4


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Basic Information Top
Gene Symbol:STRN4 ( FLJ35594,ZIN,zinedin )
Gene Full Name: striatin, calmodulin binding protein 4
Band: 19q13.32
Quick LinksEntrez ID:29888; OMIM: NA; Uniprot ID:STRN4_HUMAN; ENSEMBL ID: ENSG00000090372; HGNC ID: 15721
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst6 / 6231996
fetus32 / 56401256
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult119 / 193912161
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor8 / 9417884
cervical tumor3 / 3436687
chondrosarcoma5 / 8282360
colorectal tumor14 / 114246122
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor41 / 263845155
glioma15 / 106883140
head and neck tumor13 / 13630295
kidney tumor8 / 68959116
leukemia6 / 9584262
liver tumor2 / 9635920
lung tumor9 / 10312787
lymphoma6 / 7175583
non-neoplasia1 / 9725010
normal196 / 336030758
ovarian tumor5 / 7668265
pancreatic tumor18 / 104616172
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer12 / 102680116
retinoblastoma3 / 4635664
skin tumor15 / 124949120
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites2 / 4001549
bladder5 / 29757168
blood7 / 12347856
bone3 / 7165541
bone marrow0 / 488010 
brain61 / 110098955
cervix5 / 48171103
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue16 / 21572274
esophagus2 / 2020998
eye7 / 21105433
heart8 / 8962689
intestine23 / 23447298
kidney11 / 21177751
larynx1 / 2414541
liver4 / 20774319
lung20 / 33697459
lymph1 / 4427022
lymph node2 / 9161021
mammary gland9 / 15327158
mouth7 / 67052104
muscle5 / 10771546
nerve1 / 1576863
ovary13 / 102051127
pancreas24 / 214812111
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta24 / 28082585
prostate15 / 18934579
salivary gland4 / 20155198
skin19 / 21057490
spleen16 / 53952296
stomach0 / 966190 
testis30 / 33044290
thymus11 / 81131135
thyroid4 / 4747384
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord1 / 1368073
uterus17 / 23287872
vascular0 / 517800 
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217903_at
Cell line Expression level Expression bar
721_B_lymphoblasts16.7
Adipocyte16.2
AdrenalCortex16.95
Adrenalgland13.8
Amygdala24.9
Appendix15.35
AtrioventricularNode10.95
BDCA4+_DentriticCells13.2
Bonemarrow13.85
BronchialEpithelialCells18.45
CD105+_Endothelial14.25
CD14+_Monocytes41.05
CD19+_BCells(neg._sel.)21.65
CD33+_Myeloid23.2
CD34+21.1
CD4+_Tcells10.1
CD56+_NKCells14.3
CD71+_EarlyErythroid13.4
CD8+_Tcells12.8
CardiacMyocytes21.4
Caudatenucleus20.4
Cerebellum13.15
CerebellumPeduncles17.75
CiliaryGanglion11.45
CingulateCortex19.3
Colorectaladenocarcinoma32.85
DorsalRootGanglion9.75
FetalThyroid16.1
Fetalbrain25.9
Fetalliver12.85
Fetallung22
GlobusPallidus8.35
Heart25
Hypothalamus14.2
Kidney13.45
Leukemia_chronicMyelogenousK-56220.85
Leukemia_promyelocytic-HL-6016.3
Leukemialymphoblastic(MOLT-4)22.95
Liver21.75
Lung18.2
Lymphnode11.7
Lymphoma_burkitts(Daudi)25.85
Lymphoma_burkitts(Raji)58.55
MedullaOblongata14.95
OccipitalLobe14.75
OlfactoryBulb11.9
Ovary7.65
Pancreas11.6
PancreaticIslet17.5
ParietalLobe17.4
Pituitary12.75
Placenta17.65
Pons17
PrefrontalCortex50.35
Prostate22.9
Salivarygland11.9
SkeletalMuscle19.05
Skin10.2
SmoothMuscle18.55
Spinalcord17.05
SubthalamicNucleus15
SuperiorCervicalGanglion18.2
TemporalLobe21.2
Testis27.5
TestisGermCell86.4
TestisIntersitial60.8
TestisLeydigCell19.35
TestisSeminiferousTubule45.3
Thalamus16.45
Thymus12.85
Thyroid23.25
Tongue13.8
Tonsil15.95
Trachea12.6
TrigeminalGanglion15.9
Uterus12.8
UterusCorpus14.55
WholeBlood39.2
Wholebrain28.05
colon15.3
pineal_day19.78
pineal_night16.48
retina21.525
small_intestine14.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11014_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.92 ± 0.52
Basal Forebrain4.34 ± 0.18
Basal Part of Pons4.13 ± 0.48
Cerebellar Cortex4.14 ± 0.62
Cerebellar Nuclei3.98 ± 0.58
Claustrum4.96 ± 0.73
Epithalamus3.94 ± 0.27
Frontal Lobe4.22 ± 0.53
Globus Pallidus3.86 ± 0.3
Hypothalamus3.9 ± 0.38
Insula4.12 ± 0.6
Limbic Lobe4.76 ± 0.54
Mesencephalon4.25 ± 0.49
Myelencephalon4.38 ± 0.54
Occipital Lobe4.61 ± 0.48
Parietal Lobe4.41 ± 0.54
Pontine Tegmentum4.32 ± 0.63
Striatum4.67 ± 0.47
Subthalamus3.8 ± 0.12
Temporal Lobe4.47 ± 0.44
Thalamus4.12 ± 0.47
White Matter4.14 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Strn4CBCerebellum0
0
Strn4CTXCerebral cortex0
0
Strn4HIPHippocampal region0
0
Strn4HPFHippocampal formation0
0
Strn4HYHypothalamus0
0
Strn4LSXLateral septal complex0
0
Strn4MBMidbrain0
0
Strn4MYMedulla0
0
Strn4OLFOlfactory bulb0
0
Strn4PPons0
0
Strn4PALPallidum0
0
Strn4RHPRetrohippocampal region0
0
Strn4sAMYStriatum-like amygdalar nuclei0
0
Strn4STRStriatum0
0
Strn4STRdStriatum dorsal region0
0
Strn4STRvStriatum ventral region0
0
Strn4THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000121 41 6 46 AAAAVAAAASSCRPLGSGAGPGPTGAAPVSAPAPGPGPAGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018