Annotation Detail for EEF2K
Basic Information Top
| Gene Symbol: | EEF2K ( HSU93850,MGC45041,eEF-2K ) |
|---|---|
| Gene Full Name: | eukaryotic elongation factor-2 kinase |
| Band: | 16p12.2 |
| Quick Links | Entrez ID:29904; OMIM: 606968; Uniprot ID:EF2K_HUMAN; ENSEMBL ID: ENSG00000103319; HGNC ID: 24615 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.498892
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 11 / 564012 | 19 | |
| neonate | 0 / 31097 | 0 | |
| infant | 2 / 23620 | 84 |  |
| juvenile | 1 / 55556 | 17 | |
| adult | 71 / 1939121 | 36 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 7 / 114246 | 61 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 8 / 263845 | 30 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 9 / 136302 | 66 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 1 / 96359 | 10 |  |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 3 / 71755 | 41 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 93 / 3360307 | 27 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 4 / 90257 | 44 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 2 / 13106 | 152 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 2 / 123478 | 16 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 25 / 1100989 | 22 | |
| cervix | 4 / 48171 | 83 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 3 / 215722 | 13 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 8 / 211054 | 37 | |
| heart | 3 / 89626 | 33 | |
| intestine | 9 / 234472 | 38 | |
| kidney | 2 / 211777 | 9 | |
| larynx | 1 / 24145 | 41 | |
| liver | 4 / 207743 | 19 | |
| lung | 4 / 336974 | 11 | |
| lymph | 3 / 44270 | 67 | |
| lymph node | 6 / 91610 | 65 | |
| mammary gland | 6 / 153271 | 39 | |
| mouth | 4 / 67052 | 59 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 10 / 280825 | 35 | |
| prostate | 9 / 189345 | 47 | |
| salivary gland | 3 / 20155 | 148 | |
| skin | 18 / 210574 | 85 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 1 / 96619 | 10 | |
| testis | 4 / 330442 | 12 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 9 / 232878 | 38 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_23_P140792
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.25 ± 1.02 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.51 ± 0.57 | |
| Basal Part of Pons | 1.99 ± 0.53 | |
| Cerebellar Cortex | 2.4 ± 0.4 | |
| Cerebellar Nuclei | 1.94 ± 0.75 | |
| Claustrum | 2.36 ± 0.9 | |
| Epithalamus | 1.77 ± 0.75 | |
| Frontal Lobe | 1.73 ± 0.73 | |
| Globus Pallidus | 1.79 ± 0.59 | |
| Hypothalamus | 1.71 ± 0.71 | |
| Insula | 1.46 ± 0.6 | |
| Limbic Lobe | 1.8 ± 0.7 | |
| Mesencephalon | 1.98 ± 0.65 | |
| Myelencephalon | 1.92 ± 0.66 | |
| Occipital Lobe | 2.03 ± 0.71 | |
| Parietal Lobe | 1.8 ± 0.68 | |
| Pontine Tegmentum | 1.62 ± 0.73 | |
| Striatum | 1.69 ± 0.77 | |
| Subthalamus | 2.07 ± 0.69 | |
| Temporal Lobe | 1.66 ± 0.63 | |
| Thalamus | 1.85 ± 0.66 | |
| White Matter | 2.02 ± 0.62 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Eef2k | CB | Cerebellum | 0.79 | |
| 2.02 | | |||
| Eef2k | CTX | Cerebral cortex | 21.61 | |
| 16.05 | | |||
| Eef2k | HIP | Hippocampal region | 23.54 | |
| 28.15 | | |||
| Eef2k | HPF | Hippocampal formation | 19.56 | |
| 20.92 | | |||
| Eef2k | HY | Hypothalamus | 5.39 | |
| 4.26 | | |||
| Eef2k | LSX | Lateral septal complex | 9.2 | |
| 6.86 | | |||
| Eef2k | MB | Midbrain | 0.79 | |
| 1.39 | | |||
| Eef2k | MY | Medulla | 0.33 | |
| 0.71 | | |||
| Eef2k | OLF | Olfactory bulb | 9.1 | |
| 7.6 | | |||
| Eef2k | P | Pons | 1.13 | |
| 2.4 | | |||
| Eef2k | PAL | Pallidum | 5.67 | |
| 5.72 | | |||
| Eef2k | RHP | Retrohippocampal region | 10.8 | |
| 8.69 | | |||
| Eef2k | sAMY | Striatum-like amygdalar nuclei | 9.9 | |
| 7.22 | | |||
| Eef2k | STR | Striatum | 3.37 | |
| 2.64 | | |||
| Eef2k | STRd | Striatum dorsal region | 2.03 | |
| 1.77 | | |||
| Eef2k | STRv | Striatum ventral region | 1.22 | |
| 0.96 | | |||
| Eef2k | TH | Thalamus | 3.19 | |
| 3.25 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| EF2K_HUMAN_2 | 8 | 2 | 9 | ADEDLIFR | PRIDE |
| PAp00072577 | 18 | 407 | 424 | LDHLHWPVFSDLDNMASR | Peptide Atlas |