AutismKB 2.0

Annotation Detail for C7orf68


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Basic Information Top
Gene Symbol:C7orf68 ( FLJ21076,HIG-2,HIG2,MGC138388 )
Gene Full Name: chromosome 7 open reading frame 68
Band: 7q32.1
Quick LinksEntrez ID:29923; OMIM: NA; Uniprot ID:HIG2_HUMAN; ENSEMBL ID: ENSG00000135245; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult58 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor9 / 11936975
germ cell tumor6 / 26384522
glioma11 / 106883102
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor6 / 10312758
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal84 / 336030724
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood4 / 12347832
bone1 / 7165513
bone marrow0 / 488010 
brain37 / 110098933
cervix2 / 4817141
connective tissue1 / 1492556
ear1 / 1621261
embryonic tissue13 / 21572260
esophagus1 / 2020949
eye13 / 21105461
heart1 / 8962611
intestine2 / 2344728
kidney9 / 21177742
larynx1 / 2414541
liver2 / 2077439
lung15 / 33697444
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth2 / 6705229
muscle1 / 1077159
nerve0 / 157680 
ovary8 / 10205178
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta9 / 28082532
prostate3 / 18934515
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach8 / 9661982
testis4 / 33044212
thymus5 / 8113161
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus12 / 23287851
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218507_at
Cell line Expression level Expression bar
721_B_lymphoblasts130.95
Adipocyte51.45
AdrenalCortex8.6
Adrenalgland7.1
Amygdala11.3
Appendix17.6
AtrioventricularNode8.75
BDCA4+_DentriticCells11.7
Bonemarrow11.4
BronchialEpithelialCells16.85
CD105+_Endothelial16.6
CD14+_Monocytes8.2
CD19+_BCells(neg._sel.)10.45
CD33+_Myeloid14.9
CD34+25.1
CD4+_Tcells9.5
CD56+_NKCells12.25
CD71+_EarlyErythroid10.75
CD8+_Tcells7.7
CardiacMyocytes13.3
Caudatenucleus9.05
Cerebellum8.65
CerebellumPeduncles9.65
CiliaryGanglion125.2
CingulateCortex9.7
Colorectaladenocarcinoma10.05
DorsalRootGanglion11.45
FetalThyroid9.25
Fetalbrain33
Fetalliver9.15
Fetallung99.25
GlobusPallidus10.05
Heart12.35
Hypothalamus12.8
Kidney8.65
Leukemia_chronicMyelogenousK-5627.3
Leukemia_promyelocytic-HL-60118.7
Leukemialymphoblastic(MOLT-4)29.4
Liver13
Lung25.15
Lymphnode9.7
Lymphoma_burkitts(Daudi)17.3
Lymphoma_burkitts(Raji)51.35
MedullaOblongata9.05
OccipitalLobe6.85
OlfactoryBulb70.4
Ovary101.2
Pancreas44.8
PancreaticIslet185
ParietalLobe8.6
Pituitary11.9
Placenta29.8
Pons10.95
PrefrontalCortex17.4
Prostate15.85
Salivarygland9.2
SkeletalMuscle18.65
Skin26.6
SmoothMuscle16.75
Spinalcord45.05
SubthalamicNucleus28.9
SuperiorCervicalGanglion41.65
TemporalLobe42.7
Testis10.75
TestisGermCell24.8
TestisIntersitial9.2
TestisLeydigCell11.45
TestisSeminiferousTubule23.05
Thalamus14.65
Thymus6.9
Thyroid12.95
Tongue67.35
Tonsil8.3
Trachea16.65
TrigeminalGanglion71.05
Uterus9.55
UterusCorpus10.35
WholeBlood9.05
Wholebrain9
colon8.45
pineal_day15.56
pineal_night14.48
retina22.375
small_intestine9.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12601_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.95 ± 0.61
Basal Forebrain3.92 ± 0.57
Basal Part of Pons4.17 ± 0.61
Cerebellar Cortex4.22 ± 0.46
Cerebellar Nuclei3.77 ± 0.48
Claustrum3.57 ± 0.62
Epithalamus4.23 ± 0.65
Frontal Lobe4.03 ± 0.56
Globus Pallidus4.91 ± 0.34
Hypothalamus3.97 ± 0.65
Insula4.06 ± 0.45
Limbic Lobe3.73 ± 0.59
Mesencephalon4.04 ± 0.61
Myelencephalon3.97 ± 0.59
Occipital Lobe3.74 ± 0.64
Parietal Lobe3.84 ± 0.6
Pontine Tegmentum3.81 ± 0.58
Striatum3.48 ± 0.6
Subthalamus3.76 ± 0.61
Temporal Lobe4.05 ± 0.57
Thalamus3.84 ± 0.62
White Matter3.48 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2310016C08RikCBCerebellum0
0
2310016C08RikCTXCerebral cortex0
0
2310016C08RikHIPHippocampal region0
0
2310016C08RikHPFHippocampal formation0
0
2310016C08RikHYHypothalamus0
0
2310016C08RikLSXLateral septal complex0
0
2310016C08RikMBMidbrain0
0
2310016C08RikMYMedulla0
0
2310016C08RikOLFOlfactory bulb0
0
2310016C08RikPPons0
0
2310016C08RikPALPallidum0
0
2310016C08RikRHPRetrohippocampal region0
0
2310016C08RiksAMYStriatum-like amygdalar nuclei0
0
2310016C08RikSTRStriatum0
0
2310016C08RikSTRdStriatum dorsal region0
0
2310016C08RikSTRvStriatum ventral region0
0
2310016C08RikTHThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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