AutismKB 2.0

Annotation Detail for OSGIN1


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Basic Information Top
Gene Symbol:OSGIN1 ( BDGI,OKL38 )
Gene Full Name: oxidative stress induced growth inhibitor 1
Band: 16q23.3
Quick LinksEntrez ID:29948; OMIM: 607975; Uniprot ID:OSGI1_HUMAN; ENSEMBL ID: ENSG00000140961; HGNC ID: 30093
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult47 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal62 / 336030718
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer16 / 102680155
retinoblastoma0 / 463560 
skin tumor9 / 12494972
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain20 / 110098918
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye2 / 2110549
heart1 / 8962611
intestine4 / 23447217
kidney2 / 2117779
larynx0 / 241450 
liver4 / 20774319
lung11 / 33697432
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary4 / 10205139
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate16 / 18934584
salivary gland1 / 2015549
skin9 / 21057442
spleen1 / 5395218
stomach0 / 966190 
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219475_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.85
Adipocyte10.2
AdrenalCortex13.55
Adrenalgland19.3
Amygdala7.05
Appendix9.05
AtrioventricularNode12.55
BDCA4+_DentriticCells7.7
Bonemarrow10.2
BronchialEpithelialCells8.1
CD105+_Endothelial8.85
CD14+_Monocytes9.65
CD19+_BCells(neg._sel.)10.35
CD33+_Myeloid10.4
CD34+10.35
CD4+_Tcells9.05
CD56+_NKCells9.55
CD71+_EarlyErythroid8.8
CD8+_Tcells7.8
CardiacMyocytes12.45
Caudatenucleus8.5
Cerebellum7.2
CerebellumPeduncles30.65
CiliaryGanglion13.1
CingulateCortex11.95
Colorectaladenocarcinoma8.3
DorsalRootGanglion10.1
FetalThyroid8.65
Fetalbrain9.2
Fetalliver8.2
Fetallung6.6
GlobusPallidus14.2
Heart12.15
Hypothalamus12.45
Kidney8
Leukemia_chronicMyelogenousK-56210.9
Leukemia_promyelocytic-HL-609.75
Leukemialymphoblastic(MOLT-4)7
Liver36.1
Lung10.9
Lymphnode7.55
Lymphoma_burkitts(Daudi)11.8
Lymphoma_burkitts(Raji)11.9
MedullaOblongata7.95
OccipitalLobe9.75
OlfactoryBulb7.05
Ovary6.95
Pancreas8.9
PancreaticIslet9.6
ParietalLobe14.7
Pituitary12.6
Placenta8.65
Pons21.15
PrefrontalCortex8.95
Prostate9.7
Salivarygland7.15
SkeletalMuscle10.7
Skin11.5
SmoothMuscle10
Spinalcord17.95
SubthalamicNucleus18.75
SuperiorCervicalGanglion10.15
TemporalLobe15.65
Testis7.3
TestisGermCell6.8
TestisIntersitial7.5
TestisLeydigCell9.3
TestisSeminiferousTubule7.95
Thalamus24.1
Thymus6.35
Thyroid9.3
Tongue9.1
Tonsil8.85
Trachea8.65
TrigeminalGanglion12.95
Uterus6.5
UterusCorpus8.15
WholeBlood8.55
Wholebrain6.8
colon7.4
pineal_day10.38
pineal_night9.76
retina9.975
small_intestine7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6834_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.85 ± 1.13
Basal Forebrain2.32 ± 0.29
Basal Part of Pons2.03 ± 0.58
Cerebellar Cortex2.4 ± 0.78
Cerebellar Nuclei2.7 ± 0.67
Claustrum2.98 ± 0.7
Epithalamus2.11 ± 0.67
Frontal Lobe2.26 ± 0.68
Globus Pallidus3.06 ± 0.58
Hypothalamus2.31 ± 0.56
Insula2.1 ± 0.56
Limbic Lobe2.43 ± 0.66
Mesencephalon2.54 ± 0.73
Myelencephalon2.5 ± 0.69
Occipital Lobe2.6 ± 0.7
Parietal Lobe2.46 ± 0.71
Pontine Tegmentum2.49 ± 0.65
Striatum2.72 ± 0.66
Subthalamus2.61 ± 0.66
Temporal Lobe2.26 ± 0.68
Thalamus2.41 ± 0.68
White Matter3.29 ± 0.61
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1700012B18RikCBCerebellum5.65
6.46
1700012B18RikCTXCerebral cortex13.67
9.12
1700012B18RikHIPHippocampal region11.96
10.32
1700012B18RikHPFHippocampal formation16.9
13.4
1700012B18RikHYHypothalamus11.68
9.46
1700012B18RikLSXLateral septal complex15.95
10.43
1700012B18RikMBMidbrain5.47
5.31
1700012B18RikMYMedulla24.63
27.07
1700012B18RikOLFOlfactory bulb43.89
36.25
1700012B18RikPPons17.45
18.19
1700012B18RikPALPallidum10.26
8.33
1700012B18RikRHPRetrohippocampal region30.29
21.21
1700012B18RiksAMYStriatum-like amygdalar nuclei19.57
13.72
1700012B18RikSTRStriatum7.15
4.74
1700012B18RikSTRdStriatum dorsal region2.38
1.48
1700012B18RikSTRvStriatum ventral region11.03
6.94
1700012B18RikTHThalamus11.26
8.46
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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