AutismKB 2.0

Annotation Detail for DPP7


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Basic Information Top
Gene Symbol:DPP7 ( DPP2,DPPII,QPP )
Gene Full Name: dipeptidyl-peptidase 7
Band: 9q34.3
Quick LinksEntrez ID:29952; OMIM: 610537; Uniprot ID:DPP2_HUMAN; ENSEMBL ID: ENSG00000176978; HGNC ID: 14892
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus30 / 56401253
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult205 / 1939121105
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor8 / 9417884
cervical tumor4 / 34366116
chondrosarcoma5 / 8282360
colorectal tumor14 / 114246122
esophageal tumor2 / 17290115
gastrointestinal tumor15 / 119369125
germ cell tumor2 / 2638457
glioma13 / 106883121
head and neck tumor0 / 1363020 
kidney tumor12 / 68959174
leukemia8 / 9584283
liver tumor2 / 9635920
lung tumor24 / 103127232
lymphoma7 / 7175597
non-neoplasia8 / 9725082
normal220 / 336030765
ovarian tumor6 / 7668278
pancreatic tumor14 / 104616133
primitive neuroectodermal tumor of the CNS40 / 125680318
prostate cancer13 / 102680126
retinoblastoma1 / 4635621
skin tumor33 / 124949264
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland1 / 3319730
ascites5 / 40015124
bladder2 / 2975767
blood21 / 123478170
bone4 / 7165555
bone marrow0 / 488010 
brain81 / 110098973
cervix16 / 48171332
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus2 / 2020998
eye25 / 211054118
heart5 / 8962655
intestine17 / 23447272
kidney24 / 211777113
larynx0 / 241450 
liver3 / 20774314
lung38 / 336974112
lymph0 / 442700 
lymph node1 / 9161010
mammary gland10 / 15327165
mouth0 / 670520 
muscle1 / 1077159
nerve2 / 15768126
ovary9 / 10205188
pancreas23 / 214812107
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate17 / 18934589
salivary gland0 / 201550 
skin37 / 210574175
spleen4 / 5395274
stomach13 / 96619134
testis9 / 33044227
thymus4 / 8113149
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord1 / 1368073
uterus15 / 23287864
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14957_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.57 ± 0.55
Basal Forebrain8.11 ± 0.22
Basal Part of Pons8.22 ± 0.41
Cerebellar Cortex8.09 ± 0.41
Cerebellar Nuclei7.96 ± 0.24
Claustrum7.25 ± 0.41
Epithalamus8.69 ± 0.52
Frontal Lobe8.16 ± 0.41
Globus Pallidus7.92 ± 0.13
Hypothalamus8.36 ± 0.3
Insula8.07 ± 0.37
Limbic Lobe7.93 ± 0.4
Mesencephalon7.95 ± 0.41
Myelencephalon8.04 ± 0.39
Occipital Lobe7.9 ± 0.33
Parietal Lobe8.06 ± 0.33
Pontine Tegmentum7.94 ± 0.34
Striatum8.3 ± 0.36
Subthalamus7.96 ± 0.32
Temporal Lobe8.01 ± 0.31
Thalamus8.11 ± 0.29
White Matter8.05 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dpp7CBCerebellum0
0
Dpp7CTXCerebral cortex0
0
Dpp7HIPHippocampal region0
0
Dpp7HPFHippocampal formation0
0
Dpp7HYHypothalamus0
0
Dpp7LSXLateral septal complex0
0
Dpp7MBMidbrain0
0
Dpp7MYMedulla0
0
Dpp7OLFOlfactory bulb0
0
Dpp7PPons0
0
Dpp7PALPallidum0
0
Dpp7RHPRetrohippocampal region0
0
Dpp7sAMYStriatum-like amygdalar nuclei0
0
Dpp7STRStriatum0
0
Dpp7STRdStriatum dorsal region0
0
Dpp7STRvStriatum ventral region0
0
Dpp7THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DPP2_HUMAN_0 0 0 0 GHTELLTVEQALADFAELLR PRIDE
DPP2_HUMAN_113 11 113 123 SLPFGAQSTQR PRIDE
DPP2_HUMAN_123 20 123 142 GHTELLTVEQALADFAELLR PRIDE
DPP2_HUMAN_124 20 124 143 GHTELLTVEQALADFAELLR PRIDE
DPP2_HUMAN_203 12 203 214 DVTADFEGQSPK PRIDE
DPP2_HUMAN_254 10 254 263 DLTQLFMFAR PRIDE
DPP2_HUMAN_26 9 26 34 APDPGFQER PRIDE
DPP2_HUMAN_327 18 327 344 LYHSCADPTGCGTGPDAR PRIDE
DPP2_HUMAN_57 6 57 62 FLVSDR PRIDE
DPP2_HUMAN_98 10 98 107 GALLVFAEHR PRIDE
PAp00008729 23 241 263 WEFGTCQPLSDEKDLTQLFMFAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018