AutismKB 2.0

Annotation Detail for LRP12


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Basic Information Top
Gene Symbol:LRP12 ( DKFZp781F1053,FLJ12929,ST7 )
Gene Full Name: low density lipoprotein receptor-related protein 12
Band: 8q22.3
Quick LinksEntrez ID:29967; OMIM: NA; Uniprot ID:LRP12_HUMAN; ENSEMBL ID: ENSG00000147650; HGNC ID: 31708
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus12 / 56401221
neonate0 / 310970 
infant4 / 23620169
juvenile1 / 5555617
adult21 / 193912110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal45 / 336030713
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone2 / 7165527
bone marrow1 / 4880120
brain28 / 110098925
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine1 / 2344724
kidney1 / 2117774
larynx2 / 2414582
liver2 / 2077439
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220254_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.5
Adipocyte12.25
AdrenalCortex24.25
Adrenalgland13
Amygdala10.95
Appendix25.75
AtrioventricularNode23.25
BDCA4+_DentriticCells10.2
Bonemarrow18.05
BronchialEpithelialCells12.6
CD105+_Endothelial12.35
CD14+_Monocytes16.1
CD19+_BCells(neg._sel.)13
CD33+_Myeloid14.85
CD34+14.15
CD4+_Tcells10.5
CD56+_NKCells13.15
CD71+_EarlyErythroid13.8
CD8+_Tcells9.7
CardiacMyocytes37.35
Caudatenucleus11.75
Cerebellum11.05
CerebellumPeduncles20.65
CiliaryGanglion25.95
CingulateCortex14.9
Colorectaladenocarcinoma12.15
DorsalRootGanglion19.5
FetalThyroid15.75
Fetalbrain12.2
Fetalliver11.8
Fetallung8.8
GlobusPallidus15.05
Heart32.05
Hypothalamus12.5
Kidney14.6
Leukemia_chronicMyelogenousK-56211.7
Leukemia_promyelocytic-HL-6011.45
Leukemialymphoblastic(MOLT-4)9.25
Liver29.2
Lung14.25
Lymphnode10.2
Lymphoma_burkitts(Daudi)18.95
Lymphoma_burkitts(Raji)23.6
MedullaOblongata11
OccipitalLobe12
OlfactoryBulb10.05
Ovary12.9
Pancreas12.6
PancreaticIslet15.1
ParietalLobe18.9
Pituitary15.25
Placenta11.6
Pons16
PrefrontalCortex14.05
Prostate14.15
Salivarygland12.2
SkeletalMuscle33.25
Skin19.8
SmoothMuscle17.1
Spinalcord13.9
SubthalamicNucleus16.05
SuperiorCervicalGanglion32.65
TemporalLobe13.95
Testis10.9
TestisGermCell9.55
TestisIntersitial12.75
TestisLeydigCell15.7
TestisSeminiferousTubule12.55
Thalamus14.85
Thymus8.85
Thyroid13.45
Tongue24.05
Tonsil14.25
Trachea10.35
TrigeminalGanglion27.35
Uterus9.85
UterusCorpus18.35
WholeBlood13.45
Wholebrain9.7
colon11.65
pineal_day14.58
pineal_night15
retina15.575
small_intestine10.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P8906
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.38 ± 0.68
Basal Forebrain7.28 ± 0.24
Basal Part of Pons7.17 ± 0.35
Cerebellar Cortex7.36 ± 0.15
Cerebellar Nuclei7.04 ± 0.41
Claustrum7.43 ± 0.36
Epithalamus7.21 ± 0.31
Frontal Lobe7.5 ± 0.46
Globus Pallidus5.84 ± 0.4
Hypothalamus7.38 ± 0.28
Insula7.41 ± 0.33
Limbic Lobe7.62 ± 0.6
Mesencephalon7.12 ± 0.46
Myelencephalon7.25 ± 0.5
Occipital Lobe7.18 ± 0.61
Parietal Lobe7.53 ± 0.4
Pontine Tegmentum7.33 ± 0.4
Striatum7.63 ± 0.46
Subthalamus7.28 ± 0.27
Temporal Lobe7.24 ± 0.38
Thalamus6.81 ± 0.31
White Matter5.72 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lrp12CBCerebellum11.2
15.18
Lrp12CTXCerebral cortex19.25
15.16
Lrp12HIPHippocampal region22.96
30.35
Lrp12HPFHippocampal formation18.12
21
Lrp12HYHypothalamus1.75
1.63
Lrp12LSXLateral septal complex1.8
1.45
Lrp12MBMidbrain7.15
7.77
Lrp12MYMedulla15.87
19.44
Lrp12OLFOlfactory bulb25.7
25.3
Lrp12PPons9.25
12.83
Lrp12PALPallidum4.32
4.34
Lrp12RHPRetrohippocampal region10.15
8.37
Lrp12sAMYStriatum-like amygdalar nuclei1.55
1.51
Lrp12STRStriatum12.25
9.12
Lrp12STRdStriatum dorsal region15.31
11.22
Lrp12STRvStriatum ventral region12.38
9.64
Lrp12THThalamus8.49
8.07
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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