AutismKB 2.0

Annotation Detail for PSAT1


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Basic Information Top
Gene Symbol:PSAT1 ( EPIP,MGC1460,PSA,PSAT )
Gene Full Name: phosphoserine aminotransferase 1
Band: 9q21.2
Quick LinksEntrez ID:29968; OMIM: 610936; Uniprot ID:SERC_HUMAN; ENSEMBL ID: ENSG00000135069; HGNC ID: 19129
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body23 / 70761325
blastocyst11 / 62319176
fetus39 / 56401269
neonate5 / 31097160
infant4 / 23620169
juvenile18 / 55556323
adult141 / 193912172
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor6 / 9417863
cervical tumor26 / 34366756
chondrosarcoma7 / 8282384
colorectal tumor14 / 114246122
esophageal tumor4 / 17290231
gastrointestinal tumor17 / 119369142
germ cell tumor46 / 263845174
glioma7 / 10688365
head and neck tumor3 / 13630222
kidney tumor5 / 6895972
leukemia10 / 95842104
liver tumor17 / 96359176
lung tumor23 / 103127223
lymphoma39 / 71755543
non-neoplasia13 / 97250133
normal403 / 3360307119
ovarian tumor6 / 7668278
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer4 / 10268038
retinoblastoma11 / 46356237
skin tumor7 / 12494956
soft tissue/muscle tissue tumor33 / 125191263
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites10 / 40015249
bladder2 / 2975767
blood13 / 123478105
bone9 / 71655125
bone marrow6 / 48801122
brain297 / 1100989269
cervix26 / 48171539
connective tissue9 / 14925560
ear1 / 1621261
embryonic tissue52 / 215722241
esophagus4 / 20209197
eye19 / 21105490
heart3 / 8962633
intestine21 / 23447289
kidney17 / 21177780
larynx2 / 2414582
liver23 / 207743110
lung31 / 33697491
lymph31 / 44270700
lymph node3 / 9161032
mammary gland7 / 15327145
mouth0 / 670520 
muscle18 / 107715167
nerve0 / 157680 
ovary12 / 102051117
pancreas14 / 21481265
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta10 / 28082535
prostate5 / 18934526
salivary gland1 / 2015549
skin19 / 21057490
spleen0 / 539520 
stomach5 / 9661951
testis26 / 33044278
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus16 / 23287868
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220892_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts549.55
Adipocyte23.1
AdrenalCortex6.8
Adrenalgland8.6
Amygdala46.85
Appendix9.9
AtrioventricularNode5.5
BDCA4+_DentriticCells6.5
Bonemarrow7.9
BronchialEpithelialCells100.2
CD105+_Endothelial5.4
CD14+_Monocytes5.5
CD19+_BCells(neg._sel.)5.4
CD33+_Myeloid7.55
CD34+6.6
CD4+_Tcells6.5
CD56+_NKCells5.1
CD71+_EarlyErythroid5.85
CD8+_Tcells6.1
CardiacMyocytes227.85
Caudatenucleus21.8
Cerebellum12.5
CerebellumPeduncles11.25
CiliaryGanglion4.5
CingulateCortex12.05
Colorectaladenocarcinoma207.05
DorsalRootGanglion5.35
FetalThyroid5.55
Fetalbrain14.95
Fetalliver15.2
Fetallung6.5
GlobusPallidus5.85
Heart13.55
Hypothalamus27.85
Kidney29.2
Leukemia_chronicMyelogenousK-5628.95
Leukemia_promyelocytic-HL-6020.95
Leukemialymphoblastic(MOLT-4)13.2
Liver25.1
Lung7.6
Lymphnode5.05
Lymphoma_burkitts(Daudi)56.05
Lymphoma_burkitts(Raji)110.35
MedullaOblongata20.45
OccipitalLobe24.8
OlfactoryBulb6.7
Ovary4.5
Pancreas35.2
PancreaticIslet6.75
ParietalLobe19.45
Pituitary7.65
Placenta5.5
Pons13.55
PrefrontalCortex30.75
Prostate8.1
Salivarygland6.45
SkeletalMuscle7.9
Skin5
SmoothMuscle50.2
Spinalcord27.9
SubthalamicNucleus8.55
SuperiorCervicalGanglion8.5
TemporalLobe7.3
Testis5.35
TestisGermCell8.25
TestisIntersitial5.4
TestisLeydigCell6.7
TestisSeminiferousTubule5.25
Thalamus9.7
Thymus5.6
Thyroid8
Tongue6.65
Tonsil6.15
Trachea6.65
TrigeminalGanglion7.4
Uterus6.2
UterusCorpus7.5
WholeBlood8.85
Wholebrain91.55
colon6.95
pineal_day9.76
pineal_night13.24
retina97.2
small_intestine7.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7983_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.58 ± 0.57
Basal Forebrain5.37 ± 0.42
Basal Part of Pons4.56 ± 0.43
Cerebellar Cortex4.42 ± 0.45
Cerebellar Nuclei5.2 ± 0.76
Claustrum4.77 ± 0.5
Epithalamus5.83 ± 0.39
Frontal Lobe4.95 ± 0.57
Globus Pallidus6.02 ± 0.35
Hypothalamus5.03 ± 0.69
Insula4.91 ± 0.44
Limbic Lobe4.84 ± 0.7
Mesencephalon5.05 ± 0.45
Myelencephalon5.06 ± 0.67
Occipital Lobe4.95 ± 0.6
Parietal Lobe4.9 ± 0.64
Pontine Tegmentum5.16 ± 0.55
Striatum5.62 ± 0.47
Subthalamus5.03 ± 0.59
Temporal Lobe4.8 ± 0.61
Thalamus5.29 ± 0.43
White Matter6.79 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Psat1CBCerebellum70.03
48.77
Psat1CTXCerebral cortex44.13
20.13
Psat1HIPHippocampal region43.89
27.26
Psat1HPFHippocampal formation44.71
24.2
Psat1HYHypothalamus57.5
22.58
Psat1LSXLateral septal complex39.95
16.02
Psat1MBMidbrain86.46
40.93
Psat1MYMedulla100
59.67
Psat1OLFOlfactory bulb51.13
26.77
Psat1PPons100
62.96
Psat1PALPallidum63.99
28.37
Psat1RHPRetrohippocampal region44.83
19.14
Psat1sAMYStriatum-like amygdalar nuclei40.65
17.65
Psat1STRStriatum56.47
26.76
Psat1STRdStriatum dorsal region65.5
32.87
Psat1STRvStriatum ventral region34.13
12.73
Psat1THThalamus74.5
33.27
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000836 13 98 110 CADYVVTGAWSAK Peptide Atlas
SERC_HUMAN_116 11 116 126 KFGTINIVHPK PRIDE
SERC_HUMAN_117 10 117 126 FGTINIVHPK PRIDE
SERC_HUMAN_16 11 16 26 LPHSVLLEIQK PRIDE
SERC_HUMAN_16 17 16 32 LPHSVLLEIQKELLDYK PRIDE
SERC_HUMAN_169 21 169 189 GAVLVCDMSSNFLSKPVDVSK PRIDE
SERC_HUMAN_169 31 169 199 GAVLVCDMSSNFLSKPVDVSKFGVIFAGAQK PRIDE
SERC_HUMAN_190 10 190 199 FGVIFAGAQK PRIDE
SERC_HUMAN_200 13 200 212 NVGSAGVTVVIVR PRIDE
SERC_HUMAN_298 8 298 305 SKMNIPFR PRIDE
SERC_HUMAN_299 8 299 306 SKMNIPFR PRIDE
SERC_HUMAN_306 13 306 318 IGNAKGDDALEKR PRIDE
SERC_HUMAN_319 14 319 332 FLDKALELNMLSLK PRIDE
SERC_HUMAN_323 10 323 332 ALELNMLSLK PRIDE
SERC_HUMAN_33 12 33 44 GVGISVLEMSHR PRIDE
SERC_HUMAN_342 14 342 355 ASLYNAVTIEDVQK PRIDE
SERC_HUMAN_362 8 362 369 KFLEMHQL PRIDE
SERC_HUMAN_363 7 363 369 FLEMHQL PRIDE
SERC_HUMAN_46 16 46 61 SSDFAKIINNTENLVR PRIDE
SERC_HUMAN_5 28 5 32 QVVNFGPGPAKLPHSVLLEIQKELLDYK PRIDE
SERC_HUMAN_51 10 51 60 IINNTENLVR PRIDE
SERC_HUMAN_6 14 6 19 QVVNFGPGPAKLPH PRIDE
SERC_HUMAN_61 10 61 70 ELLAVPDNYK PRIDE
SERC_HUMAN_71 23 71 93 VIFLQGGGCGQFSAVPLNLIGLK PRIDE
SERC_HUMAN_80 18 80 97 CGQFSAVPLNLIGLKAGR PRIDE
SERC_HUMAN_97 13 97 109 CADYVVTGAWSAK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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