AutismKB 2.0

Annotation Detail for MDFIC


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Basic Information Top
Gene Symbol:MDFIC ( HIC )
Gene Full Name: MyoD family inhibitor domain containing
Band: 7q31.1-q31.2
Quick LinksEntrez ID:29969; OMIM: NA; Uniprot ID:MDFIC_HUMAN; ENSEMBL ID: ENSG00000135272; HGNC ID: 28870
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal76 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood1 / 1234788
bone3 / 7165541
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine3 / 23447212
kidney6 / 21177728
larynx0 / 241450 
liver2 / 2077439
lung14 / 33697441
lymph0 / 442700 
lymph node18 / 91610196
mammary gland4 / 15327126
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate4 / 18934521
salivary gland0 / 201550 
skin6 / 21057428
spleen1 / 5395218
stomach1 / 9661910
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus6 / 23287825
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211675_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts99.15
Adipocyte173.85
AdrenalCortex13.45
Adrenalgland9.8
Amygdala9.1
Appendix12.45
AtrioventricularNode8.95
BDCA4+_DentriticCells409
Bonemarrow9.4
BronchialEpithelialCells8.9
CD105+_Endothelial9.95
CD14+_Monocytes24.05
CD19+_BCells(neg._sel.)213.9
CD33+_Myeloid25.15
CD34+53.4
CD4+_Tcells191.9
CD56+_NKCells29.65
CD71+_EarlyErythroid8.35
CD8+_Tcells245.9
CardiacMyocytes25.45
Caudatenucleus8.55
Cerebellum7.5
CerebellumPeduncles10.85
CiliaryGanglion9.25
CingulateCortex9.5
Colorectaladenocarcinoma9
DorsalRootGanglion7.85
FetalThyroid14.85
Fetalbrain8.6
Fetalliver8
Fetallung22.9
GlobusPallidus7.75
Heart12.9
Hypothalamus10.35
Kidney7.65
Leukemia_chronicMyelogenousK-5627.95
Leukemia_promyelocytic-HL-608.55
Leukemialymphoblastic(MOLT-4)6.7
Liver12.2
Lung10
Lymphnode43.3
Lymphoma_burkitts(Daudi)12.4
Lymphoma_burkitts(Raji)13.05
MedullaOblongata8.1
OccipitalLobe8.4
OlfactoryBulb20.95
Ovary6.3
Pancreas7.4
PancreaticIslet9.85
ParietalLobe10.05
Pituitary14
Placenta9.8
Pons9.85
PrefrontalCortex10.75
Prostate11.95
Salivarygland23.85
SkeletalMuscle16.6
Skin8.2
SmoothMuscle24.95
Spinalcord18.45
SubthalamicNucleus8.5
SuperiorCervicalGanglion11.3
TemporalLobe8.35
Testis7.6
TestisGermCell7.2
TestisIntersitial7.6
TestisLeydigCell9
TestisSeminiferousTubule8
Thalamus9.4
Thymus7.55
Thyroid59.35
Tongue13.05
Tonsil27.95
Trachea11.45
TrigeminalGanglion11.3
Uterus34.15
UterusCorpus9.6
WholeBlood137
Wholebrain7.15
colon21.6
pineal_day11.16
pineal_night11
retina16.225
small_intestine16.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P120567
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.42 ± 1.04
Basal Forebrain3.14 ± 0.66
Basal Part of Pons2.55 ± 0.63
Cerebellar Cortex2.73 ± 0.67
Cerebellar Nuclei3.41 ± 0.96
Claustrum3.31 ± 0.76
Epithalamus4.7 ± 0.95
Frontal Lobe3.3 ± 0.79
Globus Pallidus4.64 ± 0.28
Hypothalamus3.35 ± 0.68
Insula3.09 ± 0.68
Limbic Lobe2.95 ± 0.77
Mesencephalon3.36 ± 0.8
Myelencephalon3.28 ± 0.83
Occipital Lobe2.96 ± 0.69
Parietal Lobe3.02 ± 0.79
Pontine Tegmentum3.12 ± 0.65
Striatum3.19 ± 0.91
Subthalamus3.22 ± 1.06
Temporal Lobe2.97 ± 0.81
Thalamus3.27 ± 0.66
White Matter3.17 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MdficCBCerebellum29.56
35.47
MdficCTXCerebral cortex74.51
56.09
MdficHIPHippocampal region45.89
54.04
MdficHPFHippocampal formation62.02
65.81
MdficHYHypothalamus45.58
36.69
MdficLSXLateral septal complex27.09
15.98
MdficMBMidbrain23.42
20.48
MdficMYMedulla39.61
42.2
MdficOLFOlfactory bulb78.71
61.78
MdficPPons27.59
31.33
MdficPALPallidum43.71
36.79
MdficRHPRetrohippocampal region97.52
90.38
MdficsAMYStriatum-like amygdalar nuclei63.5
40.84
MdficSTRStriatum63.48
43.76
MdficSTRdStriatum dorsal region58.81
40.57
MdficSTRvStriatum ventral region91.56
63.18
MdficTHThalamus40.52
33.62
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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