AutismKB 2.0

Annotation Detail for GYS2


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Basic Information Top
Gene Symbol:GYS2 ( - )
Gene Full Name: glycogen synthase 2 (liver)
Band: 12p12.1
Quick LinksEntrez ID:2998; OMIM: 138571; Uniprot ID:GYS2_HUMAN; ENSEMBL ID: ENSG00000111713; HGNC ID: 4707
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult23 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor19 / 96359197
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal26 / 33603077
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver33 / 207743158
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214621_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.95
Adipocyte5
AdrenalCortex5.8
Adrenalgland4.45
Amygdala5.3
Appendix5.55
AtrioventricularNode4.45
BDCA4+_DentriticCells5.4
Bonemarrow5.35
BronchialEpithelialCells5
CD105+_Endothelial5.15
CD14+_Monocytes5.45
CD19+_BCells(neg._sel.)5.35
CD33+_Myeloid6.45
CD34+6.4
CD4+_Tcells5.5
CD56+_NKCells5.8
CD71+_EarlyErythroid4.8
CD8+_Tcells4.75
CardiacMyocytes7.3
Caudatenucleus4.6
Cerebellum4.2
CerebellumPeduncles5.95
CiliaryGanglion3.95
CingulateCortex5.3
Colorectaladenocarcinoma5.1
DorsalRootGanglion4.2
FetalThyroid5
Fetalbrain5
Fetalliver32.15
Fetallung4.05
GlobusPallidus3.85
Heart7.2
Hypothalamus5.45
Kidney4.3
Leukemia_chronicMyelogenousK-5624.6
Leukemia_promyelocytic-HL-604.55
Leukemialymphoblastic(MOLT-4)4
Liver38.95
Lung5.6
Lymphnode4.3
Lymphoma_burkitts(Daudi)6.65
Lymphoma_burkitts(Raji)7.55
MedullaOblongata4.65
OccipitalLobe4.6
OlfactoryBulb4.05
Ovary3.5
Pancreas4.2
PancreaticIslet5.5
ParietalLobe5.55
Pituitary5.9
Placenta5.15
Pons4.95
PrefrontalCortex6.25
Prostate5.9
Salivarygland4.2
SkeletalMuscle7.05
Skin4.25
SmoothMuscle5.75
Spinalcord5.45
SubthalamicNucleus4.8
SuperiorCervicalGanglion6.55
TemporalLobe4.7
Testis4.4
TestisGermCell4.2
TestisIntersitial4.3
TestisLeydigCell5.15
TestisSeminiferousTubule4.35
Thalamus5.3
Thymus3.95
Thyroid6.25
Tongue5.3
Tonsil5
Trachea4.25
TrigeminalGanglion5.5
Uterus4.15
UterusCorpus4.8
WholeBlood5.55
Wholebrain4.2
colon5.15
pineal_day6.4
pineal_night6.22
retina6.175
small_intestine4.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14585_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.01 ± 1.17
Basal Forebrain2.34 ± 0.25
Basal Part of Pons2.11 ± 0.48
Cerebellar Cortex2.2 ± 0.62
Cerebellar Nuclei2.59 ± 0.86
Claustrum3.24 ± 0.91
Epithalamus2.23 ± 0.76
Frontal Lobe2.17 ± 0.8
Globus Pallidus2.65 ± 0.29
Hypothalamus2.46 ± 0.87
Insula2.11 ± 0.5
Limbic Lobe2.29 ± 0.72
Mesencephalon2.61 ± 0.83
Myelencephalon2.41 ± 0.9
Occipital Lobe2.49 ± 0.79
Parietal Lobe2.46 ± 1.2
Pontine Tegmentum2.37 ± 0.81
Striatum2.48 ± 0.62
Subthalamus2.39 ± 0.73
Temporal Lobe2.35 ± 1.04
Thalamus2.41 ± 0.87
White Matter2.49 ± 0.28
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018