AutismKB 2.0

Annotation Detail for GLTSCR2


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Basic Information Top
Gene Symbol:GLTSCR2 ( PICT-1,PICT1 )
Gene Full Name: glioma tumor suppressor candidate region gene 2
Band: 19q13.3
Quick LinksEntrez ID:29997; OMIM: 605691; Uniprot ID:GSCR2_HUMAN; ENSEMBL ID: ENSG00000105373; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body40 / 70761565
blastocyst38 / 62319609
fetus141 / 564012249
neonate0 / 310970 
infant1 / 2362042
juvenile12 / 55556215
adult521 / 1939121268
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor8 / 12794625
bladder carcinoma2 / 17475114
breast (mammary gland) tumor21 / 94178222
cervical tumor19 / 34366552
chondrosarcoma36 / 82823434
colorectal tumor46 / 114246402
esophageal tumor2 / 17290115
gastrointestinal tumor62 / 119369519
germ cell tumor98 / 263845371
glioma67 / 106883626
head and neck tumor4 / 13630229
kidney tumor16 / 68959232
leukemia76 / 95842792
liver tumor28 / 96359290
lung tumor71 / 103127688
lymphoma88 / 717551226
non-neoplasia14 / 97250143
normal840 / 3360307249
ovarian tumor22 / 76682286
pancreatic tumor48 / 104616458
primitive neuroectodermal tumor of the CNS59 / 125680469
prostate cancer22 / 102680214
retinoblastoma40 / 46356862
skin tumor88 / 124949704
soft tissue/muscle tissue tumor59 / 125191471
uterine tumor26 / 90257288
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland10 / 33197301
ascites16 / 40015399
bladder3 / 29757100
blood35 / 123478283
bone32 / 71655446
bone marrow4 / 4880181
brain162 / 1100989147
cervix20 / 48171415
connective tissue39 / 149255261
ear0 / 162120 
embryonic tissue126 / 215722584
esophagus2 / 2020998
eye137 / 211054649
heart25 / 89626278
intestine93 / 234472396
kidney49 / 211777231
larynx0 / 241450 
liver32 / 207743154
lung115 / 336974341
lymph82 / 442701852
lymph node81 / 91610884
mammary gland24 / 153271156
mouth0 / 670520 
muscle28 / 107715259
nerve9 / 15768570
ovary37 / 102051362
pancreas74 / 214812344
parathyroid13 / 20539632
pharynx1 / 4132824
pituitary gland10 / 16585602
placenta64 / 280825227
prostate33 / 189345174
salivary gland3 / 20155148
skin121 / 210574574
spleen13 / 53952240
stomach51 / 96619527
testis21 / 33044263
thymus7 / 8113186
thyroid2 / 4747342
tonsil17 / 169991000
trachea1 / 5241319
umbilical cord0 / 136800 
uterus67 / 232878287
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217807_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts2420.45
Adipocyte1089.45
AdrenalCortex1732
Adrenalgland1742.6
Amygdala599.95
Appendix2064.15
AtrioventricularNode283.5
BDCA4+_DentriticCells5295
Bonemarrow1551.2
BronchialEpithelialCells918.95
CD105+_Endothelial2756.4
CD14+_Monocytes3313.9
CD19+_BCells(neg._sel.)8201.15
CD33+_Myeloid3395.8
CD34+6394.55
CD4+_Tcells7528.9
CD56+_NKCells7069
CD71+_EarlyErythroid803.15
CD8+_Tcells6264.05
CardiacMyocytes504.1
Caudatenucleus542.8
Cerebellum638.45
CerebellumPeduncles988.6
CiliaryGanglion326.65
CingulateCortex429.35
Colorectaladenocarcinoma3082.65
DorsalRootGanglion379.75
FetalThyroid3191.2
Fetalbrain1344.35
Fetalliver682.3
Fetallung1886.4
GlobusPallidus161.1
Heart2826.6
Hypothalamus1148.85
Kidney883.9
Leukemia_chronicMyelogenousK-5621998.7
Leukemia_promyelocytic-HL-601722.05
Leukemialymphoblastic(MOLT-4)3607.65
Liver4156.5
Lung7122.15
Lymphnode4067.25
Lymphoma_burkitts(Daudi)4838.15
Lymphoma_burkitts(Raji)5816.9
MedullaOblongata289.85
OccipitalLobe353.3
OlfactoryBulb1248.4
Ovary2506.1
Pancreas3199.95
PancreaticIslet4111.85
ParietalLobe264.85
Pituitary1934.5
Placenta1155.65
Pons269.55
PrefrontalCortex1374.35
Prostate8460
Salivarygland2535.85
SkeletalMuscle304.35
Skin1898.6
SmoothMuscle1040.3
Spinalcord1132.85
SubthalamicNucleus291.8
SuperiorCervicalGanglion245.4
TemporalLobe379.65
Testis1447.35
TestisGermCell1075.05
TestisIntersitial684.9
TestisLeydigCell622.2
TestisSeminiferousTubule977.3
Thalamus597.95
Thymus3698.9
Thyroid6241.25
Tongue1682.25
Tonsil2015.2
Trachea2338.05
TrigeminalGanglion315.55
Uterus4698.95
UterusCorpus1489.25
WholeBlood3527.3
Wholebrain1047.3
colon2240.15
pineal_day1845.88
pineal_night1438.08
retina2106.7
small_intestine2053.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P39131
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.81 ± 0.35
Basal Forebrain7.2 ± 0.32
Basal Part of Pons7.27 ± 0.23
Cerebellar Cortex7.23 ± 0.31
Cerebellar Nuclei7.01 ± 0.24
Claustrum6.68 ± 0.54
Epithalamus7.3 ± 0.39
Frontal Lobe6.93 ± 0.38
Globus Pallidus7.56 ± 0.25
Hypothalamus6.91 ± 0.4
Insula6.96 ± 0.27
Limbic Lobe6.78 ± 0.39
Mesencephalon7.04 ± 0.36
Myelencephalon7.04 ± 0.34
Occipital Lobe6.98 ± 0.32
Parietal Lobe6.97 ± 0.39
Pontine Tegmentum6.82 ± 0.4
Striatum7.1 ± 0.42
Subthalamus6.89 ± 0.55
Temporal Lobe6.93 ± 0.32
Thalamus7.03 ± 0.3
White Matter7.73 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gltscr2CBCerebellum26.07
34.13
Gltscr2CTXCerebral cortex48.86
40.66
Gltscr2HIPHippocampal region39.08
65
Gltscr2HPFHippocampal formation40.48
53.21
Gltscr2HYHypothalamus11.9
11.41
Gltscr2LSXLateral septal complex2.66
1.96
Gltscr2MBMidbrain22.04
22.96
Gltscr2MYMedulla26.48
33.3
Gltscr2OLFOlfactory bulb20.53
18.82
Gltscr2PPons27.18
32.9
Gltscr2PALPallidum8.23
8.24
Gltscr2RHPRetrohippocampal region43.92
35.06
Gltscr2sAMYStriatum-like amygdalar nuclei16.76
12.65
Gltscr2STRStriatum10.17
8.25
Gltscr2STRdStriatum dorsal region9.92
7.96
Gltscr2STRvStriatum ventral region11.48
9.88
Gltscr2THThalamus13.94
15.83
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00072474 18 51 68 LAQEPLGLEVDQFLEDVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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