AutismKB 2.0

Annotation Detail for SLC40A1


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Basic Information Top
Gene Symbol:SLC40A1 ( FPN1,HFE4,IREG1,MST079,MTP1,SLC11A3 )
Gene Full Name: solute carrier family 40 (iron-regulated transporter), member 1
Band: 2q32.2
Quick LinksEntrez ID:30061; OMIM: 604653; Uniprot ID:S40A1_HUMAN; ENSEMBL ID: ENSG00000138449; HGNC ID: 10909
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst1 / 6231916
fetus95 / 564012168
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult294 / 1939121151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma10 / 82823120
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor5 / 26384518
glioma5 / 10688346
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor5 / 9635951
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia11 / 97250113
normal404 / 3360307120
ovarian tumor4 / 7668252
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor41 / 90257454
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland7 / 33197210
ascites5 / 40015124
bladder4 / 29757134
blood14 / 123478113
bone5 / 7165569
bone marrow2 / 4880140
brain31 / 110098928
cervix1 / 4817120
connective tissue17 / 149255113
ear4 / 16212246
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye7 / 21105433
heart14 / 89626156
intestine14 / 23447259
kidney15 / 21177770
larynx0 / 241450 
liver47 / 207743226
lung23 / 33697468
lymph0 / 442700 
lymph node1 / 9161010
mammary gland9 / 15327158
mouth0 / 670520 
muscle65 / 107715603
nerve2 / 15768126
ovary7 / 10205168
pancreas20 / 21481293
parathyroid20 / 20539973
pharynx12 / 41328290
pituitary gland0 / 165850 
placenta72 / 280825256
prostate4 / 18934521
salivary gland0 / 201550 
skin4 / 21057418
spleen12 / 53952222
stomach8 / 9661982
testis20 / 33044260
thymus3 / 8113136
thyroid4 / 4747384
tonsil0 / 169990 
trachea14 / 52413267
umbilical cord0 / 136800 
uterus56 / 232878240
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P151454
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.24 ± 1.02
Basal Forebrain1.87 ± 0.3
Basal Part of Pons1.48 ± 0.35
Cerebellar Cortex1.64 ± 0.59
Cerebellar Nuclei2.1 ± 0.74
Claustrum2.78 ± 0.91
Epithalamus1.57 ± 0.73
Frontal Lobe1.67 ± 0.75
Globus Pallidus2.42 ± 0.49
Hypothalamus1.85 ± 0.69
Insula1.96 ± 1.1
Limbic Lobe1.8 ± 0.67
Mesencephalon1.99 ± 0.67
Myelencephalon1.84 ± 0.66
Occipital Lobe1.85 ± 0.63
Parietal Lobe1.79 ± 0.62
Pontine Tegmentum1.88 ± 0.7
Striatum2 ± 0.66
Subthalamus1.97 ± 0.67
Temporal Lobe1.72 ± 0.58
Thalamus1.8 ± 0.55
White Matter2.18 ± 0.22
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018