AutismKB 2.0

Annotation Detail for ANXA1


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Basic Information Top
Gene Symbol:ANXA1 ( ANX1,LPC1 )
Gene Full Name: annexin A1
Band: 9q21.13
Quick LinksEntrez ID:301; OMIM: 151690; Uniprot ID:ANXA1_HUMAN; ENSEMBL ID: ENSG00000135046; HGNC ID: 533
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body28 / 70761395
blastocyst3 / 6231948
fetus48 / 56401285
neonate4 / 31097128
infant3 / 23620127
juvenile7 / 55556125
adult816 / 1939121420
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma14 / 17475801
breast (mammary gland) tumor5 / 9417853
cervical tumor23 / 34366669
chondrosarcoma116 / 828231400
colorectal tumor14 / 114246122
esophageal tumor11 / 17290636
gastrointestinal tumor147 / 1193691231
germ cell tumor6 / 26384522
glioma42 / 106883392
head and neck tumor133 / 136302975
kidney tumor7 / 68959101
leukemia34 / 95842354
liver tumor151 / 963591567
lung tumor27 / 103127261
lymphoma2 / 7175527
non-neoplasia30 / 97250308
normal832 / 3360307247
ovarian tumor14 / 76682182
pancreatic tumor24 / 104616229
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer11 / 102680107
retinoblastoma0 / 463560 
skin tumor18 / 124949144
soft tissue/muscle tissue tumor114 / 125191910
uterine tumor42 / 90257465
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue12 / 13106915
adrenal gland3 / 3319790
ascites57 / 400151424
bladder16 / 29757537
blood32 / 123478259
bone84 / 716551172
bone marrow21 / 48801430
brain101 / 110098991
cervix25 / 48171518
connective tissue63 / 149255422
ear3 / 16212185
embryonic tissue41 / 215722190
esophagus16 / 20209791
eye24 / 211054113
heart25 / 89626278
intestine42 / 234472179
kidney19 / 21177789
larynx29 / 241451201
liver191 / 207743919
lung110 / 336974326
lymph0 / 442700 
lymph node42 / 91610458
mammary gland25 / 153271163
mouth34 / 67052507
muscle21 / 107715194
nerve5 / 15768317
ovary10 / 10205197
pancreas25 / 214812116
parathyroid4 / 20539194
pharynx81 / 413281959
pituitary gland3 / 16585180
placenta294 / 2808251046
prostate17 / 18934589
salivary gland12 / 20155595
skin50 / 210574237
spleen3 / 5395255
stomach55 / 96619569
testis8 / 33044224
thymus11 / 81131135
thyroid51 / 474731074
tonsil0 / 169990 
trachea24 / 52413457
umbilical cord2 / 13680146
uterus172 / 232878738
vascular29 / 51780560
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201012_at
Cell line Expression level Expression bar
721_B_lymphoblasts60.6
Adipocyte2757.3
AdrenalCortex31.1
Adrenalgland22.7
Amygdala20.4
Appendix138.25
AtrioventricularNode123.85
BDCA4+_DentriticCells295.95
Bonemarrow188.4
BronchialEpithelialCells3153.2
CD105+_Endothelial82.45
CD14+_Monocytes2859.4
CD19+_BCells(neg._sel.)24.4
CD33+_Myeloid3871.65
CD34+759.3
CD4+_Tcells441.5
CD56+_NKCells1155.4
CD71+_EarlyErythroid12.2
CD8+_Tcells483.4
CardiacMyocytes2223.15
Caudatenucleus43.5
Cerebellum9.4
CerebellumPeduncles14.9
CiliaryGanglion631.8
CingulateCortex17.7
Colorectaladenocarcinoma18.7
DorsalRootGanglion196.6
FetalThyroid616.65
Fetalbrain17.1
Fetalliver10.3
Fetallung561.05
GlobusPallidus12.85
Heart22.45
Hypothalamus94.75
Kidney12.1
Leukemia_chronicMyelogenousK-5621692.75
Leukemia_promyelocytic-HL-609.4
Leukemialymphoblastic(MOLT-4)369.9
Liver21.05
Lung109.15
Lymphnode264.5
Lymphoma_burkitts(Daudi)17.35
Lymphoma_burkitts(Raji)19.4
MedullaOblongata15.55
OccipitalLobe14.1
OlfactoryBulb300.8
Ovary90.5
Pancreas25
PancreaticIslet84.2
ParietalLobe14.4
Pituitary294.6
Placenta3575.25
Pons114.25
PrefrontalCortex24.85
Prostate186.1
Salivarygland645.85
SkeletalMuscle55.25
Skin320.7
SmoothMuscle2659.65
Spinalcord89
SubthalamicNucleus15.85
SuperiorCervicalGanglion164.4
TemporalLobe17
Testis14.65
TestisGermCell64.95
TestisIntersitial43.05
TestisLeydigCell33
TestisSeminiferousTubule15.75
Thalamus17.6
Thymus46.65
Thyroid509.95
Tongue10857.8
Tonsil3346.95
Trachea1196.55
TrigeminalGanglion284.55
Uterus326.05
UterusCorpus399.75
WholeBlood1844.95
Wholebrain6.9
colon98.9
pineal_day63.06
pineal_night64.98
retina255.8
small_intestine69.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P94501
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.47 ± 0.85
Basal Forebrain6.13 ± 0.53
Basal Part of Pons5.79 ± 0.6
Cerebellar Cortex5.67 ± 0.43
Cerebellar Nuclei6.75 ± 0.39
Claustrum9.02 ± 0.43
Epithalamus9.55 ± 1.09
Frontal Lobe6.69 ± 0.84
Globus Pallidus7.07 ± 0.5
Hypothalamus6.43 ± 1.48
Insula7.66 ± 1.03
Limbic Lobe5.89 ± 0.67
Mesencephalon6.84 ± 0.89
Myelencephalon6.64 ± 0.96
Occipital Lobe6.58 ± 0.82
Parietal Lobe5.99 ± 0.89
Pontine Tegmentum6.49 ± 0.76
Striatum7.06 ± 1.33
Subthalamus6.47 ± 0.28
Temporal Lobe6.54 ± 0.73
Thalamus6.41 ± 0.53
White Matter5.76 ± 0.79
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Anxa1CBCerebellum2.23
4.03
Anxa1CTXCerebral cortex2.3
2.62
Anxa1HIPHippocampal region1.77
2.49
Anxa1HPFHippocampal formation2.52
3.26
Anxa1HYHypothalamus1.07
1.3
Anxa1LSXLateral septal complex1.37
1.81
Anxa1MBMidbrain3.86
7.73
Anxa1MYMedulla2.58
3.74
Anxa1OLFOlfactory bulb3
2.24
Anxa1PPons1.9
3.87
Anxa1PALPallidum1.38
1.55
Anxa1RHPRetrohippocampal region3.35
3.85
Anxa1sAMYStriatum-like amygdalar nuclei1.13
1.04
Anxa1STRStriatum1.16
1.13
Anxa1STRdStriatum dorsal region0.84
0.79
Anxa1STRvStriatum ventral region2.09
1.85
Anxa1THThalamus2.79
3.5
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ANXA1_HUMAN_0 0 0 0 AAMKGLGTDEDTLIEILASR PRIDE
ANXA1_HUMAN_0 0 0 0 AAYLQETGKPLDETLKK PRIDE
ANXA1_HUMAN_0 0 0 0 ALTGHLEEVVLALLK PRIDE
ANXA1_HUMAN_0 0 0 0 DITSDTSGDFR PRIDE
ANXA1_HUMAN_0 0 0 0 DLAKDITSDTSGDFR PRIDE
ANXA1_HUMAN_0 0 0 0 GDRSEDFGVNEDLADSDAR PRIDE
ANXA1_HUMAN_0 0 0 0 GGPGSAVSPYPTFNPSSDVAALHK PRIDE
ANXA1_HUMAN_0 0 0 0 GLGTDEDTLIEILASR PRIDE
ANXA1_HUMAN_0 0 0 0 GTDVNVFNTILTTR PRIDE
ANXA1_HUMAN_0 0 0 0 GVDEATIIDILTK PRIDE
ANXA1_HUMAN_0 0 0 0 ILVALCGGN PRIDE
ANXA1_HUMAN_0 0 0 0 KGTDVNVFNTILTTR PRIDE
ANXA1_HUMAN_0 0 0 0 MYGISLCQAILDETKGDYEK PRIDE
ANXA1_HUMAN_0 0 0 0 RKGTDVNVFNTILTTR PRIDE
ANXA1_HUMAN_0 0 0 0 SEDFGVNEDLADSDAR PRIDE
ANXA1_HUMAN_0 0 0 0 SEIDMNDIK PRIDE
ANXA1_HUMAN_0 0 0 0 TPAQFDADELR PRIDE
ANXA1_HUMAN_1 8 1 8 AMVSEFLK PRIDE
ANXA1_HUMAN_113 11 113 123 TPAQFDADELR PRIDE
ANXA1_HUMAN_113 15 113 127 TPAQFDADELRAAMK PRIDE
ANXA1_HUMAN_124 20 124 143 AAMKGLGTDEDTLIEILASR PRIDE
ANXA1_HUMAN_128 16 128 143 GLGTDEDTLIEILASR PRIDE
ANXA1_HUMAN_135 9 135 143 TLIEILASR PRIDE
ANXA1_HUMAN_162 15 162 176 DLAKDITSDTSGDFR PRIDE
ANXA1_HUMAN_166 11 166 176 DITSDTSGDFR PRIDE
ANXA1_HUMAN_177 27 177 203 NALLSLAKGDRSEDFGVNEDLADSDAR PRIDE
ANXA1_HUMAN_185 19 185 203 GDRSEDFGVNEDLADSDAR PRIDE
ANXA1_HUMAN_188 16 188 203 SEDFGVNEDLADSDAR PRIDE
ANXA1_HUMAN_189 16 189 204 SEDFGVNEDLADSDAR PRIDE
ANXA1_HUMAN_204 8 204 211 ALYEAGER PRIDE
ANXA1_HUMAN_212 16 212 227 RKGTDVNVFNTILTTR PRIDE
ANXA1_HUMAN_213 15 213 227 KGTDVNVFNTILTTR PRIDE
ANXA1_HUMAN_214 14 214 227 GTDVNVFNTILTTR PRIDE
ANXA1_HUMAN_250 12 250 261 VLDLELKGDIEK PRIDE
ANXA1_HUMAN_250 7 250 256 VLDLELK PRIDE
ANXA1_HUMAN_26 27 26 52 SSKGGPGSAVSPYPTFNPSSDVAALHK PRIDE
ANXA1_HUMAN_262 7 262 268 CLTAIVK PRIDE
ANXA1_HUMAN_269 12 269 280 CATSKPAFFAEK PRIDE
ANXA1_HUMAN_29 24 29 52 GGPGSAVSPYPTFNPSSDVAALHK PRIDE
ANXA1_HUMAN_298 14 298 311 IMVSRSEIDMNDIK PRIDE
ANXA1_HUMAN_303 14 303 316 SEIDMNDIKAFYQK PRIDE
ANXA1_HUMAN_303 9 303 311 SEIDMNDIK PRIDE
ANXA1_HUMAN_317 15 317 331 MYGISLCQAILDETK PRIDE
ANXA1_HUMAN_317 20 317 336 MYGISLCQAILDETKGDYEK PRIDE
ANXA1_HUMAN_337 9 337 345 ILVALCGGN PRIDE
ANXA1_HUMAN_58 13 58 70 GVDEATIIDILTK PRIDE
ANXA1_HUMAN_58 14 58 71 GVDEATIIDILTKR PRIDE
ANXA1_HUMAN_81 16 81 96 AAYLQETGKPLDETLK PRIDE
ANXA1_HUMAN_81 17 81 97 AAYLQETGKPLDETLKK PRIDE
ANXA1_HUMAN_9 17 9 25 QAWFIENEEQEYVQTVK PRIDE
ANXA1_HUMAN_97 16 97 112 KALTGHLEEVVLALLK PRIDE
ANXA1_HUMAN_98 15 98 112 ALTGHLEEVVLALLK PRIDE
ANXA1_HUMAN_98 26 98 123 ALTGHLEEVVLALLKTPAQFDADELR PRIDE
ANXA1_HUMAN_98 30 98 127 ALTGHLEEVVLALLKTPAQFDADELRAAMK PRIDE
PAp00000873 12 270 281 CATSKPAFFAEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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