AutismKB 2.0

Annotation Detail for HIST1H2BD


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Basic Information Top
Gene Symbol:HIST1H2BD ( H2B.1B,H2B/b,H2BFB,HIRIP2,MGC90432,dJ221C16.6 )
Gene Full Name: histone cluster 1, H2bd
Band: 6p22.2
Quick LinksEntrez ID:3017; OMIM: 602799; Uniprot ID:H2B1D_HUMAN; ENSEMBL ID: ENSG00000158373; HGNC ID: 4747
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult30 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal44 / 336030713
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain7 / 11009896
cervix0 / 481710 
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine2 / 2344728
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung12 / 33697435
lymph0 / 442700 
lymph node4 / 9161043
mammary gland4 / 15327126
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate9 / 18934547
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222067_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.95
Adipocyte15.9
AdrenalCortex9.2
Adrenalgland7.45
Amygdala7.6
Appendix31.95
AtrioventricularNode4.75
BDCA4+_DentriticCells14.1
Bonemarrow49.45
BronchialEpithelialCells9.2
CD105+_Endothelial6.7
CD14+_Monocytes9.75
CD19+_BCells(neg._sel.)52.85
CD33+_Myeloid9.2
CD34+10.7
CD4+_Tcells11.1
CD56+_NKCells9.4
CD71+_EarlyErythroid7.1
CD8+_Tcells18.35
CardiacMyocytes11.3
Caudatenucleus8
Cerebellum8.9
CerebellumPeduncles8.8
CiliaryGanglion3.75
CingulateCortex7.85
Colorectaladenocarcinoma16.35
DorsalRootGanglion5.55
FetalThyroid178.45
Fetalbrain10.1
Fetalliver27.1
Fetallung26.9
GlobusPallidus5.85
Heart11.55
Hypothalamus6.95
Kidney15.5
Leukemia_chronicMyelogenousK-56243.8
Leukemia_promyelocytic-HL-6023.75
Leukemialymphoblastic(MOLT-4)5.15
Liver14.25
Lung36.45
Lymphnode48.95
Lymphoma_burkitts(Daudi)18.1
Lymphoma_burkitts(Raji)13.25
MedullaOblongata7.3
OccipitalLobe7.3
OlfactoryBulb41.3
Ovary5.5
Pancreas15.55
PancreaticIslet18.8
ParietalLobe8.75
Pituitary26
Placenta19.2
Pons7.85
PrefrontalCortex9.3
Prostate164.35
Salivarygland46.75
SkeletalMuscle14.45
Skin6.2
SmoothMuscle10.45
Spinalcord9.3
SubthalamicNucleus6.25
SuperiorCervicalGanglion11.5
TemporalLobe8.8
Testis8.8
TestisGermCell7.3
TestisIntersitial5.8
TestisLeydigCell10.9
TestisSeminiferousTubule9.1
Thalamus8.8
Thymus79.5
Thyroid13.8
Tongue14.3
Tonsil16.4
Trachea16.2
TrigeminalGanglion11.25
Uterus34.35
UterusCorpus8.6
WholeBlood14.15
Wholebrain8.7
colon12
pineal_day10.42
pineal_night13.8
retina25.05
small_intestine23.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P146211
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.84 ± 0.22
Basal Forebrain8.06 ± 0.42
Basal Part of Pons7.86 ± 0.51
Cerebellar Cortex8.12 ± 0.36
Cerebellar Nuclei8.06 ± 0.31
Claustrum7.78 ± 0.57
Epithalamus8.21 ± 0.29
Frontal Lobe7.73 ± 0.41
Globus Pallidus8.22 ± 0.47
Hypothalamus7.87 ± 0.7
Insula7.65 ± 0.35
Limbic Lobe7.83 ± 0.29
Mesencephalon7.64 ± 0.49
Myelencephalon7.72 ± 0.43
Occipital Lobe7.52 ± 0.35
Parietal Lobe7.66 ± 0.41
Pontine Tegmentum7.74 ± 0.41
Striatum7.93 ± 0.54
Subthalamus7.22 ± 0.47
Temporal Lobe7.7 ± 0.4
Thalamus7.61 ± 0.38
White Matter8.21 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hist1h2bpCBCerebellum54.73
100
Hist1h2bpCTXCerebral cortex100
100
Hist1h2bpHIPHippocampal region100
100
Hist1h2bpHPFHippocampal formation100
100
Hist1h2bpHYHypothalamus56.74
53.62
Hist1h2bpLSXLateral septal complex100
100
Hist1h2bpMBMidbrain66.57
68.04
Hist1h2bpMYMedulla54.24
65.05
Hist1h2bpOLFOlfactory bulb100
100
Hist1h2bpPPons42.73
50.27
Hist1h2bpPALPallidum71.17
75.74
Hist1h2bpRHPRetrohippocampal region100
100
Hist1h2bpsAMYStriatum-like amygdalar nuclei100
99.4
Hist1h2bpSTRStriatum100
100
Hist1h2bpSTRdStriatum dorsal region100
100
Hist1h2bpSTRvStriatum ventral region100
100
Hist1h2bpTHThalamus96.28
99.86
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
H2B1D_HUMAN_1 29 1 29 PEPTKSAPAPKKGSKKAVTKAQKKDGKKR PRIDE
PAp00000587 15 59 73 AMGIMNSFVNDIFER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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