AutismKB 2.0

Annotation Detail for ANXA2


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Basic Information Top
Gene Symbol:ANXA2 ( ANX2,ANX2L4,CAL1H,LIP2,LPC2,LPC2D,P36,PAP-IV )
Gene Full Name: annexin A2
Band: 15q22.2
Quick LinksEntrez ID:302; OMIM: 151740; Uniprot ID:ANXA2_HUMAN; ENSEMBL ID: ENSG00000182718; HGNC ID: 537
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body42 / 70761593
blastocyst10 / 62319160
fetus129 / 564012228
neonate125 / 310974019
infant4 / 23620169
juvenile18 / 55556323
adult1434 / 1939121739
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor17 / 127941328
bladder carcinoma116 / 174756638
breast (mammary gland) tumor87 / 94178923
cervical tumor20 / 34366581
chondrosarcoma221 / 828232668
colorectal tumor133 / 1142461164
esophageal tumor11 / 17290636
gastrointestinal tumor102 / 119369854
germ cell tumor92 / 263845348
glioma83 / 106883776
head and neck tumor138 / 1363021012
kidney tumor79 / 689591145
leukemia58 / 95842605
liver tumor146 / 963591515
lung tumor117 / 1031271134
lymphoma9 / 71755125
non-neoplasia33 / 97250339
normal1242 / 3360307369
ovarian tumor132 / 766821721
pancreatic tumor319 / 1046163049
primitive neuroectodermal tumor of the CNS22 / 125680175
prostate cancer110 / 1026801071
retinoblastoma1 / 4635621
skin tumor136 / 1249491088
soft tissue/muscle tissue tumor78 / 125191623
uterine tumor106 / 902571174
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue6 / 13106457
adrenal gland20 / 33197602
ascites30 / 40015749
bladder131 / 297574402
blood24 / 123478194
bone185 / 716552581
bone marrow90 / 488011844
brain193 / 1100989175
cervix22 / 48171456
connective tissue180 / 1492551205
ear11 / 16212678
embryonic tissue83 / 215722384
esophagus12 / 20209593
eye83 / 211054393
heart32 / 89626357
intestine169 / 234472720
kidney121 / 211777571
larynx16 / 24145662
liver184 / 207743885
lung277 / 336974822
lymph2 / 4427045
lymph node27 / 91610294
mammary gland145 / 153271946
mouth44 / 67052656
muscle23 / 107715213
nerve19 / 157681204
ovary157 / 1020511538
pancreas340 / 2148121582
parathyroid37 / 205391801
pharynx45 / 413281088
pituitary gland7 / 16585422
placenta124 / 280825441
prostate162 / 189345855
salivary gland30 / 201551488
skin288 / 2105741367
spleen2 / 5395237
stomach93 / 96619962
testis36 / 330442108
thymus3 / 8113136
thyroid33 / 47473695
tonsil2 / 16999117
trachea4 / 5241376
umbilical cord92 / 136806725
uterus166 / 232878712
vascular45 / 51780869
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201590_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts1056.55
Adipocyte6086.35
AdrenalCortex382.05
Adrenalgland660.6
Amygdala65.75
Appendix862.45
AtrioventricularNode786.45
BDCA4+_DentriticCells2194.8
Bonemarrow309.65
BronchialEpithelialCells13242.3
CD105+_Endothelial218.75
CD14+_Monocytes3461
CD19+_BCells(neg._sel.)1018.15
CD33+_Myeloid4114.4
CD34+651.1
CD4+_Tcells528.4
CD56+_NKCells1719.5
CD71+_EarlyErythroid15.45
CD8+_Tcells357.8
CardiacMyocytes6385.65
Caudatenucleus74.95
Cerebellum68.55
CerebellumPeduncles45.4
CiliaryGanglion1895.3
CingulateCortex60.15
Colorectaladenocarcinoma6279.25
DorsalRootGanglion1459.3
FetalThyroid2824.85
Fetalbrain105.45
Fetalliver275.5
Fetallung2961.7
GlobusPallidus42.35
Heart283.15
Hypothalamus323.45
Kidney315.85
Leukemia_chronicMyelogenousK-562595.3
Leukemia_promyelocytic-HL-6026.95
Leukemialymphoblastic(MOLT-4)100.35
Liver131
Lung3609.95
Lymphnode979.3
Lymphoma_burkitts(Daudi)150.75
Lymphoma_burkitts(Raji)24.6
MedullaOblongata38.4
OccipitalLobe47.65
OlfactoryBulb1978.9
Ovary378.9
Pancreas1040.3
PancreaticIslet1286.3
ParietalLobe61.95
Pituitary605.7
Placenta2863.8
Pons212.95
PrefrontalCortex121
Prostate1981.35
Salivarygland847.2
SkeletalMuscle217.8
Skin1829.4
SmoothMuscle6328.75
Spinalcord862.3
SubthalamicNucleus60
SuperiorCervicalGanglion1319.8
TemporalLobe74.8
Testis507
TestisGermCell824.9
TestisIntersitial390.15
TestisLeydigCell476.8
TestisSeminiferousTubule350
Thalamus220.25
Thymus615.85
Thyroid1399.3
Tongue2835
Tonsil1787.35
Trachea1908.25
TrigeminalGanglion1505
Uterus1196.85
UterusCorpus780.45
WholeBlood1168.65
Wholebrain36.2
colon1461.4
pineal_day219.46
pineal_night259.82
retina1044.925
small_intestine1711.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P146644
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.19 ± 0.59
Basal Forebrain7.46 ± 0.47
Basal Part of Pons6.31 ± 0.43
Cerebellar Cortex6.8 ± 0.35
Cerebellar Nuclei7.54 ± 0.88
Claustrum5.98 ± 0.83
Epithalamus8.89 ± 0.56
Frontal Lobe7.4 ± 0.88
Globus Pallidus9.24 ± 0.41
Hypothalamus8.4 ± 0.56
Insula7.26 ± 0.53
Limbic Lobe6.71 ± 0.79
Mesencephalon7.62 ± 0.64
Myelencephalon7.36 ± 0.82
Occipital Lobe6.79 ± 0.81
Parietal Lobe6.85 ± 0.8
Pontine Tegmentum7.68 ± 0.88
Striatum7.94 ± 0.85
Subthalamus8.62 ± 0.36
Temporal Lobe7.1 ± 0.75
Thalamus7.89 ± 0.78
White Matter10.26 ± 0.57
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Anxa2CBCerebellum0.85
1.96
Anxa2CTXCerebral cortex0.71
1.04
Anxa2HIPHippocampal region1.02
2.26
Anxa2HPFHippocampal formation0.89
1.78
Anxa2HYHypothalamus0.52
0.67
Anxa2LSXLateral septal complex1.63
3.31
Anxa2MBMidbrain1.81
3.71
Anxa2MYMedulla4.11
10.7
Anxa2OLFOlfactory bulb1.21
1.7
Anxa2PPons2.72
7.59
Anxa2PALPallidum0.49
1.07
Anxa2RHPRetrohippocampal region0.67
1.1
Anxa2sAMYStriatum-like amygdalar nuclei0.27
0.47
Anxa2STRStriatum0.63
0.91
Anxa2STRdStriatum dorsal region0.64
0.89
Anxa2STRvStriatum ventral region0.37
0.36
Anxa2THThalamus1.14
1.86
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ANXA2_HUMAN_0 0 0 0 AEDGSVIDYELIDQDAR PRIDE
ANXA2_HUMAN_0 0 0 0 AYTNFDAER PRIDE
ANXA2_HUMAN_0 0 0 0 AYTNFDAERDALNIETAIK PRIDE
ANXA2_HUMAN_0 0 0 0 DIISDTSGDFR PRIDE
ANXA2_HUMAN_0 0 0 0 DIISDTSGDFRK PRIDE
ANXA2_HUMAN_0 0 0 0 EMYKTDLEKDIISDTSGDFR PRIDE
ANXA2_HUMAN_0 0 0 0 GLGTDEDSLIEIICSR PRIDE
ANXA2_HUMAN_0 0 0 0 GVDEVTIVNILTNR PRIDE
ANXA2_HUMAN_0 0 0 0 KLMVALAK PRIDE
ANXA2_HUMAN_0 0 0 0 LSLEGDHSTPPSAYGSVK PRIDE
ANXA2_HUMAN_0 0 0 0 RAEDGSVIDYELIDQDAR PRIDE
ANXA2_HUMAN_0 0 0 0 SALSGHLETVILGLLK PRIDE
ANXA2_HUMAN_0 0 0 0 SALSGHLETVILGLLKTPAQYDASELK PRIDE
ANXA2_HUMAN_0 0 0 0 SLYYYIQQDTK PRIDE
ANXA2_HUMAN_0 0 0 0 SLYYYIQQDTKGDYQK PRIDE
ANXA2_HUMAN_0 0 0 0 SNAQRQDIAFAYQR PRIDE
ANXA2_HUMAN_0 0 0 0 SYSPYDMLESIR PRIDE
ANXA2_HUMAN_0 0 0 0 SYSPYDMLESIRK PRIDE
ANXA2_HUMAN_0 0 0 0 TDLEKDIISDTSGDFR PRIDE
ANXA2_HUMAN_0 0 0 0 TDLEKDIISDTSGDFRK PRIDE
ANXA2_HUMAN_0 0 0 0 TKGVDEVTIVNILTNR PRIDE
ANXA2_HUMAN_0 0 0 0 TNQELQEINR PRIDE
ANXA2_HUMAN_0 0 0 0 TNQELQEINRVYK PRIDE
ANXA2_HUMAN_0 0 0 0 TPAQYDASELK PRIDE
ANXA2_HUMAN_10 18 10 27 LSLEGDHSTPPSAYGSVK PRIDE
ANXA2_HUMAN_104 11 104 114 TPAQYDASELK PRIDE
ANXA2_HUMAN_104 15 104 118 TPAQYDASELKASMK PRIDE
ANXA2_HUMAN_105 11 105 115 TPAQYDASELK PRIDE
ANXA2_HUMAN_11 18 11 28 LSLEGDHSTPPSAYGSVK PRIDE
ANXA2_HUMAN_115 20 115 134 ASMKGLGTDEDSLIEIICSR PRIDE
ANXA2_HUMAN_119 16 119 134 GLGTDEDSLIEIICSR PRIDE
ANXA2_HUMAN_120 16 120 135 GLGTDEDSLIEIICSR PRIDE
ANXA2_HUMAN_126 9 126 134 SLIEIICSR PRIDE
ANXA2_HUMAN_135 10 135 144 TNQELQEINR PRIDE
ANXA2_HUMAN_135 13 135 147 TNQELQEINRVYK PRIDE
ANXA2_HUMAN_136 10 136 145 TNQELQEINR PRIDE
ANXA2_HUMAN_145 12 145 156 VYKEMYKTDLEK PRIDE
ANXA2_HUMAN_148 20 148 167 EMYKTDLEKDIISDTSGDFR PRIDE
ANXA2_HUMAN_152 16 152 167 TDLEKDIISDTSGDFR PRIDE
ANXA2_HUMAN_152 17 152 168 TDLEKDIISDTSGDFRK PRIDE
ANXA2_HUMAN_153 16 153 168 TDLEKDIISDTSGDFR PRIDE
ANXA2_HUMAN_157 11 157 167 DIISDTSGDFR PRIDE
ANXA2_HUMAN_157 12 157 168 DIISDTSGDFRK PRIDE
ANXA2_HUMAN_157 19 157 175 DIISDTSGDFRKLMVALAK PRIDE
ANXA2_HUMAN_158 10 158 167 IISDTSGDFR PRIDE
ANXA2_HUMAN_168 8 168 175 KLMVALAK PRIDE
ANXA2_HUMAN_176 20 176 195 GRRAEDGSVIDYELIDQDAR PRIDE
ANXA2_HUMAN_178 18 178 195 RAEDGSVIDYELIDQDAR PRIDE
ANXA2_HUMAN_179 17 179 195 AEDGSVIDYELIDQDAR PRIDE
ANXA2_HUMAN_179 18 179 196 RAEDGSVIDYELIDQDAR PRIDE
ANXA2_HUMAN_179 25 179 203 AEDGSVIDYELIDQDARDLYDAGVK PRIDE
ANXA2_HUMAN_179 26 179 204 AEDGSVIDYELIDQDARDLYDAGVKR PRIDE
ANXA2_HUMAN_196 9 196 204 DLYDAGVKR PRIDE
ANXA2_HUMAN_197 8 197 204 LYDAGVKR PRIDE
ANXA2_HUMAN_205 15 205 219 KGTDVPKWISIMTER PRIDE
ANXA2_HUMAN_206 14 206 219 GTDVPKWISIMTER PRIDE
ANXA2_HUMAN_212 8 212 219 WISIMTER PRIDE
ANXA2_HUMAN_220 11 220 230 SVPHLQKVFDR PRIDE
ANXA2_HUMAN_221 10 221 230 VPHLQKVFDR PRIDE
ANXA2_HUMAN_227 6 227 232 VFDRYK PRIDE
ANXA2_HUMAN_231 14 231 244 YKSYSPYDMLESIR PRIDE
ANXA2_HUMAN_233 12 233 244 SYSPYDMLESIR PRIDE
ANXA2_HUMAN_233 13 233 245 SYSPYDMLESIRK PRIDE
ANXA2_HUMAN_233 16 233 248 SYSPYDMLESIRKEVK PRIDE
ANXA2_HUMAN_245 28 245 272 KEVKGDLENAFLNLVQCIQNKPLYFADR PRIDE
ANXA2_HUMAN_246 27 246 272 EVKGDLENAFLNLVQCIQNKPLYFADR PRIDE
ANXA2_HUMAN_249 24 249 272 GDLENAFLNLVQCIQNKPLYFADR PRIDE
ANXA2_HUMAN_28 19 28 46 AYTNFDAERDALNIETAIK PRIDE
ANXA2_HUMAN_28 21 28 48 AYTNFDAERDALNIETAIKTK PRIDE
ANXA2_HUMAN_28 9 28 36 AYTNFDAER PRIDE
ANXA2_HUMAN_29 9 29 37 AYTNFDAER PRIDE
ANXA2_HUMAN_290 12 290 301 IMVSRSEVDMLK PRIDE
ANXA2_HUMAN_296 9 296 304 SEVDMLKIR PRIDE
ANXA2_HUMAN_313 11 313 323 SLYYYIQQDTK PRIDE
ANXA2_HUMAN_313 16 313 328 SLYYYIQQDTKGDYQK PRIDE
ANXA2_HUMAN_314 11 314 324 SLYYYIQQDTK PRIDE
ANXA2_HUMAN_329 10 329 338 ALLYLCGGDD PRIDE
ANXA2_HUMAN_37 10 37 46 DALNIETAIK PRIDE
ANXA2_HUMAN_38 10 38 47 DALNIETAIK PRIDE
ANXA2_HUMAN_47 16 47 62 TKGVDEVTIVNILTNR PRIDE
ANXA2_HUMAN_49 14 49 62 GVDEVTIVNILTNR PRIDE
ANXA2_HUMAN_50 14 50 63 GVDEVTIVNILTNR PRIDE
ANXA2_HUMAN_63 14 63 76 SNAQRQDIAFAYQR PRIDE
ANXA2_HUMAN_68 10 68 77 QDIAFAYQRR PRIDE
ANXA2_HUMAN_68 9 68 76 QDIAFAYQR PRIDE
ANXA2_HUMAN_78 10 78 87 TKKELASALK PRIDE
ANXA2_HUMAN_80 24 80 103 KELASALKSALSGHLETVILGLLK PRIDE
ANXA2_HUMAN_81 23 81 103 ELASALKSALSGHLETVILGLLK PRIDE
ANXA2_HUMAN_81 34 81 114 ELASALKSALSGHLETVILGLLKTPAQYDASELK PRIDE
ANXA2_HUMAN_88 16 88 103 SALSGHLETVILGLLK PRIDE
ANXA2_HUMAN_88 27 88 114 SALSGHLETVILGLLKTPAQYDASELK PRIDE
ANXA2_HUMAN_89 16 89 104 SALSGHLETVILGLLK PRIDE
PAp00002279 27 265 291 EVKGDLENAFLNLVQCIQNKPLYFADR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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