AutismKB 2.0

Annotation Detail for HBG1


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Basic Information Top
Gene Symbol:HBG1 ( HBGA,HBGR,HSGGL1 )
Gene Full Name: hemoglobin, gamma A
Band: 11p15.4
Quick LinksEntrez ID:3047; OMIM: 142200; Uniprot ID:HBG1_HUMAN; ENSEMBL ID: ENSG00000213934; HGNC ID: 4831
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1413 / 5640122505
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult101 / 193912152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia14 / 95842146
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal1509 / 3360307449
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood12 / 12347897
bone3 / 7165541
bone marrow10 / 48801204
brain22 / 110098919
cervix0 / 481710 
connective tissue0 / 1492550 
ear15 / 16212925
embryonic tissue28 / 215722129
esophagus0 / 202090 
eye6 / 21105428
heart106 / 896261182
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver65 / 207743312
lung45 / 336974133
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary4 / 10205139
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta73 / 280825259
prostate0 / 1893450 
salivary gland2 / 2015599
skin10 / 21057447
spleen289 / 539525356
stomach0 / 966190 
testis0 / 3304420 
thymus13 / 81131160
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213515_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.35
Adipocyte4.15
AdrenalCortex4.6
Adrenalgland4.95
Amygdala4.35
Appendix103.65
AtrioventricularNode8.85
BDCA4+_DentriticCells4.6
Bonemarrow945.05
BronchialEpithelialCells4.05
CD105+_Endothelial1486.55
CD14+_Monocytes6.85
CD19+_BCells(neg._sel.)4.4
CD33+_Myeloid5.4
CD34+25.85
CD4+_Tcells4.55
CD56+_NKCells5.05
CD71+_EarlyErythroid7222.65
CD8+_Tcells4.05
CardiacMyocytes5.15
Caudatenucleus3.7
Cerebellum4.6
CerebellumPeduncles5.1
CiliaryGanglion8.15
CingulateCortex4.3
Colorectaladenocarcinoma4.1
DorsalRootGanglion8.85
FetalThyroid15663.7
Fetalbrain4482.4
Fetalliver16424.9
Fetallung12710.5
GlobusPallidus3.4
Heart24.5
Hypothalamus4.5
Kidney5.15
Leukemia_chronicMyelogenousK-5628758.25
Leukemia_promyelocytic-HL-603.65
Leukemialymphoblastic(MOLT-4)3.35
Liver5.55
Lung17.45
Lymphnode6.9
Lymphoma_burkitts(Daudi)5.4
Lymphoma_burkitts(Raji)5.75
MedullaOblongata3.9
OccipitalLobe3.8
OlfactoryBulb4.4
Ovary3.25
Pancreas3.3
PancreaticIslet4.45
ParietalLobe4.45
Pituitary8.65
Placenta10048
Pons9.7
PrefrontalCortex6.65
Prostate346.15
Salivarygland3.35
SkeletalMuscle4.85
Skin5.85
SmoothMuscle4.75
Spinalcord4.65
SubthalamicNucleus7.3
SuperiorCervicalGanglion5.2
TemporalLobe6.75
Testis3.65
TestisGermCell3.9
TestisIntersitial3.55
TestisLeydigCell4.75
TestisSeminiferousTubule4.4
Thalamus5.05
Thymus3.4
Thyroid8.65
Tongue4.4
Tonsil3.95
Trachea3.8
TrigeminalGanglion4.6
Uterus3.55
UterusCorpus3.75
WholeBlood545.8
Wholebrain4.1
colon4.05
pineal_day5.28
pineal_night5.1
retina5.325
small_intestine4.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P64539
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.93 ± 0.62
Basal Forebrain2.99 ± 0.71
Basal Part of Pons3.31 ± 0.74
Cerebellar Cortex2.84 ± 0.62
Cerebellar Nuclei3.48 ± 0.59
Claustrum3.25 ± 0.96
Epithalamus3.45 ± 0.73
Frontal Lobe3.63 ± 0.63
Globus Pallidus4.17 ± 0.75
Hypothalamus3.56 ± 0.89
Insula4.01 ± 0.49
Limbic Lobe3.65 ± 0.72
Mesencephalon3.5 ± 0.78
Myelencephalon3.48 ± 0.78
Occipital Lobe2.97 ± 0.93
Parietal Lobe3.1 ± 0.83
Pontine Tegmentum3.54 ± 0.96
Striatum3.73 ± 0.76
Subthalamus2.88 ± 0.52
Temporal Lobe3.71 ± 0.77
Thalamus3.46 ± 0.85
White Matter2.87 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hbb-bh1CBCerebellum9.83
14.38
Hbb-bh1CTXCerebral cortex7.66
7.14
Hbb-bh1HIPHippocampal region5.12
6.04
Hbb-bh1HPFHippocampal formation4.95
5.32
Hbb-bh1HYHypothalamus3.53
3.94
Hbb-bh1LSXLateral septal complex3.11
2.72
Hbb-bh1MBMidbrain4.71
5.79
Hbb-bh1MYMedulla4.77
5.69
Hbb-bh1OLFOlfactory bulb10.22
9.15
Hbb-bh1PPons4.72
6.06
Hbb-bh1PALPallidum3.36
3.51
Hbb-bh1RHPRetrohippocampal region4.72
4.27
Hbb-bh1sAMYStriatum-like amygdalar nuclei4.97
5.37
Hbb-bh1STRStriatum5.2
5.19
Hbb-bh1STRdStriatum dorsal region5.34
5.64
Hbb-bh1STRvStriatum ventral region5.43
4.24
Hbb-bh1THThalamus5.17
5.69
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
HBG1_HUMAN_18 13 18 30 VNVEDAGGETLGR PRIDE
PAp00025569 13 84 96 GTFAQLSELHCDK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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