AutismKB 2.0

Annotation Detail for HELLS


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Basic Information Top
Gene Symbol:HELLS ( FLJ10339,LSH,PASG,SMARCA6 )
Gene Full Name: helicase, lymphoid-specific
Band: 10q23.33
Quick LinksEntrez ID:3070; OMIM: 603946; Uniprot ID:HELLS_HUMAN; ENSEMBL ID: ENSG00000119969; HGNC ID: 4861
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst12 / 62319192
fetus28 / 56401249
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor25 / 26384594
glioma0 / 1068830 
head and neck tumor6 / 13630244
kidney tumor0 / 689590 
leukemia27 / 95842281
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal95 / 336030728
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder2 / 2975767
blood1 / 1234788
bone4 / 7165555
bone marrow26 / 48801532
brain6 / 11009895
cervix1 / 4817120
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue23 / 215722106
esophagus0 / 202090 
eye1 / 2110544
heart2 / 8962622
intestine1 / 2344724
kidney1 / 2117774
larynx2 / 2414582
liver11 / 20774352
lung7 / 33697420
lymph0 / 442700 
lymph node7 / 9161076
mammary gland5 / 15327132
mouth1 / 6705214
muscle5 / 10771546
nerve1 / 1576863
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach1 / 9661910
testis33 / 33044299
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11058_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.07 ± 0.6
Basal Forebrain4.86 ± 0.22
Basal Part of Pons4.41 ± 0.47
Cerebellar Cortex5.29 ± 0.33
Cerebellar Nuclei4.55 ± 0.45
Claustrum4.68 ± 0.77
Epithalamus4.54 ± 0.32
Frontal Lobe4.43 ± 0.56
Globus Pallidus4.62 ± 0.52
Hypothalamus4.77 ± 0.52
Insula4.65 ± 0.35
Limbic Lobe4.71 ± 0.53
Mesencephalon4.87 ± 0.65
Myelencephalon4.74 ± 0.56
Occipital Lobe5.03 ± 0.53
Parietal Lobe4.76 ± 0.55
Pontine Tegmentum4.63 ± 0.65
Striatum4.52 ± 0.49
Subthalamus5.08 ± 1.03
Temporal Lobe4.66 ± 0.51
Thalamus4.53 ± 0.45
White Matter5.26 ± 0.23
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00005839 22 154 175 NKKENEDENSSSTNLCVEDLQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018