AutismKB 2.0

Annotation Detail for HGF


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Basic Information Top
Gene Symbol:HGF ( DFNB39,F-TCF,HGFB,HPTA,SF )
Gene Full Name: hepatocyte growth factor (hepapoietin A; scatter factor)
Band: 7q21.11
Quick LinksEntrez ID:3082; OMIM: 142409,608265; Uniprot ID:HGF_HUMAN; ENSEMBL ID: ENSG00000019991; HGNC ID: 4893
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult60 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal76 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow4 / 4880181
brain3 / 11009892
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye4 / 21105418
heart2 / 8962622
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver7 / 20774333
lung2 / 3369745
lymph0 / 442700 
lymph node4 / 9161043
mammary gland8 / 15327152
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta37 / 280825131
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210998_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.7
Adipocyte8.55
AdrenalCortex9.1
Adrenalgland6.55
Amygdala7.15
Appendix8.65
AtrioventricularNode10.3
BDCA4+_DentriticCells7
Bonemarrow8.2
BronchialEpithelialCells6.95
CD105+_Endothelial7.1
CD14+_Monocytes7.9
CD19+_BCells(neg._sel.)7.9
CD33+_Myeloid9.3
CD34+8.95
CD4+_Tcells7.25
CD56+_NKCells8.4
CD71+_EarlyErythroid7.1
CD8+_Tcells6.25
CardiacMyocytes10.3
Caudatenucleus6.65
Cerebellum7.1
CerebellumPeduncles9.95
CiliaryGanglion6.8
CingulateCortex7.8
Colorectaladenocarcinoma7.3
DorsalRootGanglion6.1
FetalThyroid7.15
Fetalbrain6.9
Fetalliver6.4
Fetallung5.7
GlobusPallidus6
Heart11.35
Hypothalamus7.6
Kidney11.55
Leukemia_chronicMyelogenousK-5626.65
Leukemia_promyelocytic-HL-606.45
Leukemialymphoblastic(MOLT-4)6.35
Liver10.7
Lung7.9
Lymphnode5.85
Lymphoma_burkitts(Daudi)9.8
Lymphoma_burkitts(Raji)10.65
MedullaOblongata6.6
OccipitalLobe6.5
OlfactoryBulb5.7
Ovary5.2
Pancreas6.15
PancreaticIslet8
ParietalLobe15.2
Pituitary8.55
Placenta7.5
Pons7.6
PrefrontalCortex8.6
Prostate8.25
Salivarygland6.2
SkeletalMuscle12.15
Skin7.55
SmoothMuscle26.5
Spinalcord11.15
SubthalamicNucleus7.35
SuperiorCervicalGanglion11.4
TemporalLobe9.7
Testis6.25
TestisGermCell5.7
TestisIntersitial6.25
TestisLeydigCell7.6
TestisSeminiferousTubule6.3
Thalamus7.75
Thymus5.55
Thyroid8.45
Tongue8.05
Tonsil7.6
Trachea6
TrigeminalGanglion7.9
Uterus5.65
UterusCorpus7.7
WholeBlood7.9
Wholebrain6
colon7.2
pineal_day8.68
pineal_night8.5
retina8.6
small_intestine6.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16087_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.24 ± 0.84
Basal Forebrain2.51 ± 0.2
Basal Part of Pons2.72 ± 0.93
Cerebellar Cortex2.58 ± 0.87
Cerebellar Nuclei2.92 ± 0.71
Claustrum3.07 ± 0.56
Epithalamus2.54 ± 0.97
Frontal Lobe3.28 ± 0.73
Globus Pallidus2.45 ± 0.84
Hypothalamus2.66 ± 0.58
Insula3.04 ± 0.64
Limbic Lobe2.93 ± 0.73
Mesencephalon3 ± 0.81
Myelencephalon2.84 ± 0.75
Occipital Lobe2.37 ± 0.68
Parietal Lobe3.1 ± 0.73
Pontine Tegmentum2.87 ± 0.77
Striatum2.19 ± 0.73
Subthalamus4.36 ± 1.93
Temporal Lobe2.72 ± 0.76
Thalamus2.61 ± 0.66
White Matter2.22 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
HgfCBCerebellum0.29
0.66
HgfCTXCerebral cortex1.25
1.12
HgfHIPHippocampal region0.97
1.09
HgfHPFHippocampal formation0.98
1.02
HgfHYHypothalamus0.23
0.24
HgfLSXLateral septal complex0.31
0.29
HgfMBMidbrain0.43
0.58
HgfMYMedulla0.33
0.31
HgfOLFOlfactory bulb1.44
1.01
HgfPPons0.39
0.35
HgfPALPallidum0.14
0.2
HgfRHPRetrohippocampal region1.01
0.92
HgfsAMYStriatum-like amygdalar nuclei0.41
0.39
HgfSTRStriatum0.24
0.26
HgfSTRdStriatum dorsal region0.19
0.22
HgfSTRvStriatum ventral region0.22
0.24
HgfTHThalamus0.14
0.16
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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