AutismKB 2.0

Annotation Detail for CXXC1


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Basic Information Top
Gene Symbol:CXXC1 ( 2410002I16Rik,5830420C16Rik,CFP1,CGBP,HsT2645,PCCX1,PHF18,SPP1,ZCGPC1,hCGBP )
Gene Full Name: CXXC finger protein 1
Band: 18q21.1
Quick LinksEntrez ID:30827; OMIM: 609150; Uniprot ID:CXXC1_HUMAN; ENSEMBL ID: ENSG00000154832; HGNC ID: 24343
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst4 / 6231964
fetus19 / 56401233
neonate0 / 310970 
infant1 / 2362042
juvenile5 / 5555689
adult119 / 193912161
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor10 / 26384537
glioma8 / 10688374
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia13 / 95842135
liver tumor1 / 9635910
lung tumor7 / 10312767
lymphoma12 / 71755167
non-neoplasia3 / 9725030
normal134 / 336030739
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma3 / 4635664
skin tumor8 / 12494964
soft tissue/muscle tissue tumor15 / 125191119
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood14 / 123478113
bone2 / 7165527
bone marrow1 / 4880120
brain50 / 110098945
cervix5 / 48171103
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye15 / 21105471
heart2 / 8962622
intestine14 / 23447259
kidney3 / 21177714
larynx4 / 24145165
liver3 / 20774314
lung11 / 33697432
lymph7 / 44270158
lymph node10 / 91610109
mammary gland8 / 15327152
mouth0 / 670520 
muscle7 / 10771564
nerve3 / 15768190
ovary6 / 10205158
pancreas8 / 21481237
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate6 / 18934531
salivary gland0 / 201550 
skin10 / 21057447
spleen2 / 5395237
stomach6 / 9661962
testis23 / 33044269
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus15 / 23287864
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 48580_at
Cell line Expression level Expression bar
721_B_lymphoblasts92.85
Adipocyte12.35
AdrenalCortex15.7
Adrenalgland10.95
Amygdala9.2
Appendix14
AtrioventricularNode10.55
BDCA4+_DentriticCells144.9
Bonemarrow14.55
BronchialEpithelialCells9.9
CD105+_Endothelial116.4
CD14+_Monocytes61.95
CD19+_BCells(neg._sel.)67.15
CD33+_Myeloid90.35
CD34+164.55
CD4+_Tcells131.9
CD56+_NKCells193.65
CD71+_EarlyErythroid93.2
CD8+_Tcells185.85
CardiacMyocytes10.3
Caudatenucleus11.55
Cerebellum15
CerebellumPeduncles24
CiliaryGanglion9.75
CingulateCortex13.8
Colorectaladenocarcinoma7.65
DorsalRootGanglion10
FetalThyroid28.8
Fetalbrain37.65
Fetalliver11.5
Fetallung23.75
GlobusPallidus10.6
Heart17.65
Hypothalamus23
Kidney9.15
Leukemia_chronicMyelogenousK-56218.7
Leukemia_promyelocytic-HL-6014.8
Leukemialymphoblastic(MOLT-4)39.9
Liver16.4
Lung29.9
Lymphnode30.4
Lymphoma_burkitts(Daudi)28.75
Lymphoma_burkitts(Raji)39.4
MedullaOblongata11.75
OccipitalLobe11.2
OlfactoryBulb13.1
Ovary8
Pancreas10.3
PancreaticIslet15.3
ParietalLobe14.95
Pituitary15.4
Placenta16.25
Pons15.8
PrefrontalCortex17.35
Prostate22.3
Salivarygland9.9
SkeletalMuscle13.2
Skin10.4
SmoothMuscle10.85
Spinalcord23.95
SubthalamicNucleus14.3
SuperiorCervicalGanglion14.6
TemporalLobe15.75
Testis12.1
TestisGermCell12.9
TestisIntersitial11.95
TestisLeydigCell12.8
TestisSeminiferousTubule13.15
Thalamus14.85
Thymus21.45
Thyroid18.05
Tongue12.95
Tonsil25.4
Trachea9.85
TrigeminalGanglion12.65
Uterus12.85
UterusCorpus11.4
WholeBlood13.3
Wholebrain10.9
colon9.25
pineal_day22.88
pineal_night20.18
retina14.475
small_intestine9.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P141779
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.49 ± 0.22
Basal Forebrain6.96 ± 0.22
Basal Part of Pons6.72 ± 0.24
Cerebellar Cortex6.98 ± 0.23
Cerebellar Nuclei6.63 ± 0.26
Claustrum6.6 ± 0.37
Epithalamus7 ± 0.36
Frontal Lobe6.64 ± 0.31
Globus Pallidus6.8 ± 0.28
Hypothalamus6.68 ± 0.28
Insula6.67 ± 0.25
Limbic Lobe6.63 ± 0.28
Mesencephalon6.64 ± 0.35
Myelencephalon6.74 ± 0.3
Occipital Lobe6.72 ± 0.29
Parietal Lobe6.65 ± 0.27
Pontine Tegmentum6.58 ± 0.31
Striatum6.64 ± 0.32
Subthalamus6.33 ± 0.53
Temporal Lobe6.71 ± 0.29
Thalamus6.77 ± 0.21
White Matter7.14 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cxxc1CBCerebellum0
0
Cxxc1CTXCerebral cortex0
0
Cxxc1HIPHippocampal region0
0
Cxxc1HPFHippocampal formation0
0
Cxxc1HYHypothalamus0
0
Cxxc1LSXLateral septal complex0
0
Cxxc1MBMidbrain0
0
Cxxc1MYMedulla0
0
Cxxc1OLFOlfactory bulb0
0
Cxxc1PPons0
0
Cxxc1PALPallidum0
0
Cxxc1RHPRetrohippocampal region0
0
Cxxc1sAMYStriatum-like amygdalar nuclei0
0
Cxxc1STRStriatum0
0
Cxxc1STRdStriatum dorsal region0
0
Cxxc1STRvStriatum ventral region0
0
Cxxc1THThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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