AutismKB 2.0

Annotation Detail for HIP1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HIP1 ( ILWEQ,MGC126506 )
Gene Full Name: huntingtin interacting protein 1
Band: 7q11.23
Quick LinksEntrez ID:3092; OMIM: 601767; Uniprot ID:HIP1_HUMAN; ENSEMBL ID: ENSG00000127946; HGNC ID: 4913
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst3 / 6231948
fetus27 / 56401247
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult76 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor8 / 26384530
glioma6 / 10688356
head and neck tumor4 / 13630229
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal122 / 336030736
ovarian tumor9 / 76682117
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor15 / 124949120
soft tissue/muscle tissue tumor16 / 125191127
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow1 / 4880120
brain41 / 110098937
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue21 / 21572297
esophagus0 / 202090 
eye7 / 21105433
heart4 / 8962644
intestine2 / 2344728
kidney8 / 21177737
larynx0 / 241450 
liver3 / 20774314
lung14 / 33697441
lymph0 / 442700 
lymph node2 / 9161021
mammary gland5 / 15327132
mouth2 / 6705229
muscle4 / 10771537
nerve1 / 1576863
ovary10 / 10205197
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate2 / 18934510
salivary gland0 / 201550 
skin16 / 21057475
spleen0 / 539520 
stomach5 / 9661951
testis29 / 33044287
thymus0 / 811310 
thyroid2 / 4747342
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord1 / 1368073
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205426_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.4
Adipocyte4.2
AdrenalCortex4.65
Adrenalgland3.65
Amygdala5.15
Appendix4.35
AtrioventricularNode3.3
BDCA4+_DentriticCells4.9
Bonemarrow4.3
BronchialEpithelialCells4.25
CD105+_Endothelial4.35
CD14+_Monocytes4.55
CD19+_BCells(neg._sel.)4.6
CD33+_Myeloid5.55
CD34+5.45
CD4+_Tcells4.65
CD56+_NKCells5.1
CD71+_EarlyErythroid4
CD8+_Tcells4.15
CardiacMyocytes5.65
Caudatenucleus3.85
Cerebellum3.45
CerebellumPeduncles4.9
CiliaryGanglion3.1
CingulateCortex4.4
Colorectaladenocarcinoma9
DorsalRootGanglion3.4
FetalThyroid4.15
Fetalbrain4.3
Fetalliver3.75
Fetallung3.55
GlobusPallidus3.15
Heart5.7
Hypothalamus4.7
Kidney3.55
Leukemia_chronicMyelogenousK-5623.85
Leukemia_promyelocytic-HL-603.8
Leukemialymphoblastic(MOLT-4)3.45
Liver5.8
Lung4.75
Lymphnode3.7
Lymphoma_burkitts(Daudi)5.5
Lymphoma_burkitts(Raji)6.15
MedullaOblongata3.9
OccipitalLobe3.85
OlfactoryBulb3.35
Ovary2.85
Pancreas3.5
PancreaticIslet4.55
ParietalLobe4.6
Pituitary5
Placenta4.45
Pons4.05
PrefrontalCortex5.35
Prostate5.05
Salivarygland3.45
SkeletalMuscle5.15
Skin3.3
SmoothMuscle4.85
Spinalcord4.55
SubthalamicNucleus3.9
SuperiorCervicalGanglion5
TemporalLobe3.9
Testis3.7
TestisGermCell3.5
TestisIntersitial3.6
TestisLeydigCell4.25
TestisSeminiferousTubule3.65
Thalamus4.35
Thymus3.35
Thyroid5.35
Tongue4.3
Tonsil4.15
Trachea3.6
TrigeminalGanglion4.4
Uterus3.5
UterusCorpus3.9
WholeBlood4.75
Wholebrain3.7
colon4.3
pineal_day5.36
pineal_night5.3
retina5.175
small_intestine4.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P916314
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.17 ± 0.44
Basal Forebrain5.47 ± 0.51
Basal Part of Pons5.22 ± 0.47
Cerebellar Cortex5.16 ± 0.34
Cerebellar Nuclei5.47 ± 0.37
Claustrum5.61 ± 0.65
Epithalamus4.7 ± 0.59
Frontal Lobe5.15 ± 0.57
Globus Pallidus6.57 ± 0.3
Hypothalamus5.16 ± 0.51
Insula4.91 ± 0.61
Limbic Lobe5.3 ± 0.77
Mesencephalon5.47 ± 0.5
Myelencephalon5.42 ± 0.66
Occipital Lobe5.5 ± 0.58
Parietal Lobe5.31 ± 0.58
Pontine Tegmentum5.26 ± 0.64
Striatum5.7 ± 0.66
Subthalamus5.13 ± 0.31
Temporal Lobe5.21 ± 0.56
Thalamus5.57 ± 0.46
White Matter7.47 ± 0.45
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hip1CBCerebellum35.95
60.26
Hip1CTXCerebral cortex58.9
54.62
Hip1HIPHippocampal region42.38
52.41
Hip1HPFHippocampal formation53.58
54.7
Hip1HYHypothalamus57.1
49.85
Hip1LSXLateral septal complex50.27
36.83
Hip1MBMidbrain38.34
36.59
Hip1MYMedulla57.11
56.4
Hip1OLFOlfactory bulb88.67
71.13
Hip1PPons49.73
53.81
Hip1PALPallidum49.3
48.64
Hip1RHPRetrohippocampal region61.23
56.7
Hip1sAMYStriatum-like amygdalar nuclei57.64
54.34
Hip1STRStriatum57.36
53.77
Hip1STRdStriatum dorsal region55.49
52.8
Hip1STRvStriatum ventral region62.75
55.82
Hip1THThalamus39.3
35.33
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00096405 14 246 259 LHSCLPADTLQGHR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved