Annotation Detail for HLA-DQA1
Basic Information Top
| Gene Symbol: | HLA-DQA1 ( CD,CELIAC1,DQ-A1,FLJ27088,FLJ27328,GSE,HLA-DQA,MGC149527 ) |
|---|---|
| Gene Full Name: | major histocompatibility complex, class II, DQ alpha 1 |
| Band: | 6p21.32 |
| Quick Links | Entrez ID:3117; OMIM: 146880; Uniprot ID:DQA1_HUMAN; ENSEMBL ID: ENSG00000196735; HGNC ID: 4942 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.706240
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 26 / 564012 | 46 |  |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 206 / 1939121 | 106 |  |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 5 / 564012 | 8 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 50 / 1939121 | 25 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 0 / 564012 | 0 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 1 / 1939121 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 3 / 17475 | 171 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 3 / 34366 | 87 | |
| chondrosarcoma | 8 / 82823 | 96 | |
| colorectal tumor | 9 / 114246 | 78 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 6 / 119369 | 50 | |
| germ cell tumor | 2 / 263845 | 7 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 9 / 95842 | 93 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 14 / 103127 | 135 | |
| lymphoma | 53 / 71755 | 738 |  |
| non-neoplasia | 11 / 97250 | 113 | |
| normal | 311 / 3360307 | 92 | |
| ovarian tumor | 9 / 76682 | 117 | |
| pancreatic tumor | 13 / 104616 | 124 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 5 / 125191 | 39 | |
| uterine tumor | 11 / 90257 | 121 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 6 / 136302 | 44 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 9 / 95842 | 93 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 8 / 71755 | 111 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 45 / 3360307 | 13 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 1 / 90257 | 11 | |
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 0 / 3360307 | 0 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 5 / 33197 | 150 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 24 / 123478 | 194 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 20 / 1100989 | 18 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 17 / 149255 | 113 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 12 / 211054 | 56 | |
| heart | 3 / 89626 | 33 | |
| intestine | 25 / 234472 | 106 | |
| kidney | 12 / 211777 | 56 | |
| larynx | 0 / 24145 | 0 | |
| liver | 8 / 207743 | 38 | |
| lung | 77 / 336974 | 228 | |
| lymph | 27 / 44270 | 609 | |
| lymph node | 56 / 91610 | 611 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 10 / 102051 | 97 | |
| pancreas | 20 / 214812 | 93 | |
| parathyroid | 6 / 20539 | 292 | |
| pharynx | 31 / 41328 | 750 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 7 / 280825 | 24 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 4 / 210574 | 18 | |
| spleen | 7 / 53952 | 129 | |
| stomach | 41 / 96619 | 424 | |
| testis | 3 / 330442 | 9 | |
| thymus | 8 / 81131 | 98 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 20 / 16999 | 1176 |  |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 24 / 232878 | 103 | |
| vascular | 3 / 51780 | 57 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 9 / 123478 | 72 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 6 / 1100989 | 5 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 2 / 89626 | 22 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 6 / 211777 | 28 | |
| larynx | 1 / 24145 | 41 | |
| liver | 0 / 207743 | 0 | |
| lung | 22 / 336974 | 65 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 10 / 91610 | 109 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 4 / 67052 | 59 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 3 / 41328 | 72 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 3 / 96619 | 31 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 6 / 16999 | 352 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 2 / 51780 | 38 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 0 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 213831_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 307.9 | |
| Adipocyte | 5.3 | |
| AdrenalCortex | 5.75 | |
| Adrenalgland | 4.65 | |
| Amygdala | 5.4 | |
| Appendix | 5.55 | |
| AtrioventricularNode | 4.6 | |
| BDCA4+_DentriticCells | 387.55 | |
| Bonemarrow | 5.55 | |
| BronchialEpithelialCells | 5 | |
| CD105+_Endothelial | 5.4 | |
| CD14+_Monocytes | 43.85 | |
| CD19+_BCells(neg._sel.) | 197.6 | |
| CD33+_Myeloid | 20.85 | |
| CD34+ | 6.85 | |
| CD4+_Tcells | 5.9 | |
| CD56+_NKCells | 40.25 | |
| CD71+_EarlyErythroid | 5 | |
| CD8+_Tcells | 5.1 | |
| CardiacMyocytes | 6.7 | |
| Caudatenucleus | 4.85 | |
| Cerebellum | 4.35 | |
| CerebellumPeduncles | 6.2 | |
| CiliaryGanglion | 4.4 | |
| CingulateCortex | 5.55 | |
| Colorectaladenocarcinoma | 5.3 | |
| DorsalRootGanglion | 4.3 | |
| FetalThyroid | 5.2 | |
| Fetalbrain | 5.2 | |
| Fetalliver | 4.7 | |
| Fetallung | 4.5 | |
| GlobusPallidus | 4.15 | |
| Heart | 7.15 | |
| Hypothalamus | 5.8 | |
| Kidney | 4.4 | |
| Leukemia_chronicMyelogenousK-562 | 4.8 | |
| Leukemia_promyelocytic-HL-60 | 83.7 | |
| Leukemialymphoblastic(MOLT-4) | 4.3 | |
| Liver | 7.65 | |
| Lung | 5.85 | |
| Lymphnode | 101.65 | |
| Lymphoma_burkitts(Daudi) | 178.05 | |
| Lymphoma_burkitts(Raji) | 269.25 | |
| MedullaOblongata | 4.9 | |
| OccipitalLobe | 4.85 | |
| OlfactoryBulb | 4.25 | |
| Ovary | 3.55 | |
| Pancreas | 4.45 | |
| PancreaticIslet | 22 | |
| ParietalLobe | 5.65 | |
| Pituitary | 6.3 | |
| Placenta | 5.6 | |
| Pons | 6.8 | |
| PrefrontalCortex | 6.15 | |
| Prostate | 6.25 | |
| Salivarygland | 10.8 | |
| SkeletalMuscle | 7 | |
| Skin | 4.35 | |
| SmoothMuscle | 5.9 | |
| Spinalcord | 8.5 | |
| SubthalamicNucleus | 5.35 | |
| SuperiorCervicalGanglion | 6.4 | |
| TemporalLobe | 4.95 | |
| Testis | 4.6 | |
| TestisGermCell | 4.2 | |
| TestisIntersitial | 4.4 | |
| TestisLeydigCell | 5.35 | |
| TestisSeminiferousTubule | 4.55 | |
| Thalamus | 5.5 | |
| Thymus | 52.2 | |
| Thyroid | 6.85 | |
| Tongue | 5.55 | |
| Tonsil | 70.8 | |
| Trachea | 8.2 | |
| TrigeminalGanglion | 5.5 | |
| Uterus | 4.25 | |
| UterusCorpus | 5.2 | |
| WholeBlood | 11.35 | |
| Wholebrain | 4.3 | |
| colon | 16.55 | |
| pineal_day | 7.08 | |
| pineal_night | 8.5 | |
| retina | 8.8 | |
| small_intestine | 429.85 | |
- Probe name: A_24_P393230
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.12 ± 1.02 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.68 ± 0.2 | |
| Basal Part of Pons | 1.37 ± 0.41 | |
| Cerebellar Cortex | 1.48 ± 0.71 | |
| Cerebellar Nuclei | 2.02 ± 0.74 | |
| Claustrum | 2.48 ± 0.76 | |
| Epithalamus | 1.37 ± 0.72 | |
| Frontal Lobe | 1.54 ± 0.67 | |
| Globus Pallidus | 2.38 ± 0.33 | |
| Hypothalamus | 1.76 ± 0.64 | |
| Insula | 1.55 ± 0.51 | |
| Limbic Lobe | 1.71 ± 0.62 | |
| Mesencephalon | 1.82 ± 0.67 | |
| Myelencephalon | 1.75 ± 0.68 | |
| Occipital Lobe | 1.7 ± 0.48 | |
| Parietal Lobe | 1.68 ± 0.72 | |
| Pontine Tegmentum | 1.76 ± 0.75 | |
| Striatum | 1.91 ± 0.52 | |
| Subthalamus | 1.88 ± 0.64 | |
| Temporal Lobe | 1.6 ± 0.67 | |
| Thalamus | 1.68 ± 0.58 | |
| White Matter | 2.17 ± 0.32 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| H2-Aa | CB | Cerebellum | 1.77 | |
| 3.6 | | |||
| H2-Aa | CTX | Cerebral cortex | 3.04 | |
| 3.11 | | |||
| H2-Aa | HIP | Hippocampal region | 2.73 | |
| 3.09 | | |||
| H2-Aa | HPF | Hippocampal formation | 2.73 | |
| 3.05 | | |||
| H2-Aa | HY | Hypothalamus | 2.44 | |
| 2.95 | | |||
| H2-Aa | LSX | Lateral septal complex | 1.33 | |
| 1.1 | | |||
| H2-Aa | MB | Midbrain | 2.16 | |
| 4.68 | | |||
| H2-Aa | MY | Medulla | 3.61 | |
| 6.67 | | |||
| H2-Aa | OLF | Olfactory bulb | 6.84 | |
| 6.87 | | |||
| H2-Aa | P | Pons | 5.06 | |
| 8.17 | | |||
| H2-Aa | PAL | Pallidum | 2.27 | |
| 2.19 | | |||
| H2-Aa | RHP | Retrohippocampal region | 2.68 | |
| 3.02 | | |||
| H2-Aa | sAMY | Striatum-like amygdalar nuclei | 2.08 | |
| 2.36 | | |||
| H2-Aa | STR | Striatum | 1.74 | |
| 1.61 | | |||
| H2-Aa | STRd | Striatum dorsal region | 0.71 | |
| 0.69 | | |||
| H2-Aa | STRv | Striatum ventral region | 5.13 | |
| 4.21 | | |||
| H2-Aa | TH | Thalamus | 2.05 | |
| 2.11 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00004056 | 17 | 174 | 190 | ISYLTFLPSADEIYDCK | Peptide Atlas |