Annotation Detail for HLA-DRB1
Basic Information Top
| Gene Symbol: | HLA-DRB1 ( DRB1,DRw10,FLJ75017,FLJ76359,HLA-DR1B,HLA-DRB,HLA-DRB1*,SS1 ) |
|---|---|
| Gene Full Name: | major histocompatibility complex, class II, DR beta 1 |
| Band: | 6p21.32 |
| Quick Links | Entrez ID:3123; OMIM: 142857; Uniprot ID:2B1F_HUMAN; ENSEMBL ID: ENSG00000196126; HGNC ID: 4948 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.696211
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 15 / 564012 | 26 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 137 / 1939121 | 70 |  |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 28 / 564012 | 49 | |
| neonate | 3 / 31097 | 96 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 4 / 55556 | 71 | |
| adult | 628 / 1939121 | 323 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 3 / 12794 | 234 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 6 / 114246 | 52 | |
| esophageal tumor | 3 / 17290 | 173 | |
| gastrointestinal tumor | 8 / 119369 | 67 | |
| germ cell tumor | 3 / 263845 | 11 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 5 / 95842 | 52 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 14 / 103127 | 135 | |
| lymphoma | 20 / 71755 | 278 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 175 / 3360307 | 52 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 13 / 104616 | 124 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 |  |
| uterine tumor | 9 / 90257 | 99 | |
| adrenal tumor | 8 / 12794 | 625 | |
| bladder carcinoma | 9 / 17475 | 515 | |
| breast (mammary gland) tumor | 17 / 94178 | 180 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 22 / 82823 | 265 | |
| colorectal tumor | 44 / 114246 | 385 | |
| esophageal tumor | 3 / 17290 | 173 | |
| gastrointestinal tumor | 37 / 119369 | 309 | |
| germ cell tumor | 6 / 263845 | 22 | |
| glioma | 13 / 106883 | 121 | |
| head and neck tumor | 49 / 136302 | 359 | |
| kidney tumor | 27 / 68959 | 391 | |
| leukemia | 16 / 95842 | 166 | |
| liver tumor | 5 / 96359 | 51 | |
| lung tumor | 44 / 103127 | 426 | |
| lymphoma | 124 / 71755 | 1728 |  |
| non-neoplasia | 30 / 97250 | 308 | |
| normal | 762 / 3360307 | 226 | |
| ovarian tumor | 24 / 76682 | 312 | |
| pancreatic tumor | 44 / 104616 | 420 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 7 / 102680 | 68 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 6 / 124949 | 48 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 54 / 90257 | 598 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 4 / 33197 | 120 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 8 / 123478 | 64 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 25 / 1100989 | 22 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 7 / 149255 | 46 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 1 / 215722 | 4 | |
| esophagus | 4 / 20209 | 197 | |
| eye | 2 / 211054 | 9 | |
| heart | 2 / 89626 | 22 | |
| intestine | 11 / 234472 | 46 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 2 / 24145 | 82 | |
| liver | 2 / 207743 | 9 | |
| lung | 71 / 336974 | 210 | |
| lymph | 15 / 44270 | 338 | |
| lymph node | 16 / 91610 | 174 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 16 / 214812 | 74 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 12 / 41328 | 290 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 11 / 280825 | 39 | |
| prostate | 4 / 189345 | 21 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 4 / 210574 | 18 | |
| spleen | 7 / 53952 | 129 | |
| stomach | 12 / 96619 | 124 | |
| testis | 8 / 330442 | 24 | |
| thymus | 4 / 81131 | 49 | |
| thyroid | 5 / 47473 | 105 | |
| tonsil | 24 / 16999 | 1411 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 12 / 232878 | 51 | |
| vascular | 0 / 51780 | 0 | |
| adipose tissue | 4 / 13106 | 305 | |
| adrenal gland | 9 / 33197 | 271 | |
| ascites | 4 / 40015 | 99 | |
| bladder | 7 / 29757 | 235 | |
| blood | 27 / 123478 | 218 | |
| bone | 6 / 71655 | 83 | |
| bone marrow | 4 / 48801 | 81 | |
| brain | 86 / 1100989 | 78 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 32 / 149255 | 214 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 3 / 20209 | 148 | |
| eye | 30 / 211054 | 142 | |
| heart | 8 / 89626 | 89 | |
| intestine | 69 / 234472 | 294 | |
| kidney | 40 / 211777 | 188 | |
| larynx | 3 / 24145 | 124 | |
| liver | 8 / 207743 | 38 | |
| lung | 271 / 336974 | 804 | |
| lymph | 79 / 44270 | 1784 | |
| lymph node | 73 / 91610 | 796 | |
| mammary gland | 38 / 153271 | 247 | |
| mouth | 16 / 67052 | 238 | |
| muscle | 14 / 107715 | 129 | |
| nerve | 5 / 15768 | 317 | |
| ovary | 32 / 102051 | 313 | |
| pancreas | 60 / 214812 | 279 | |
| parathyroid | 7 / 20539 | 340 | |
| pharynx | 28 / 41328 | 677 | |
| pituitary gland | 2 / 16585 | 120 | |
| placenta | 10 / 280825 | 35 | |
| prostate | 28 / 189345 | 147 | |
| salivary gland | 7 / 20155 | 347 | |
| skin | 97 / 210574 | 460 | |
| spleen | 33 / 53952 | 611 | |
| stomach | 64 / 96619 | 662 | |
| testis | 12 / 330442 | 36 | |
| thymus | 24 / 81131 | 295 | |
| thyroid | 19 / 47473 | 400 | |
| tonsil | 61 / 16999 | 3588 | |
| trachea | 4 / 52413 | 76 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 81 / 232878 | 347 | |
| vascular | 9 / 51780 | 173 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204670_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6953.5 | |
| Adipocyte | 61 | |
| AdrenalCortex | 278.15 | |
| Adrenalgland | 799.9 | |
| Amygdala | 123.1 | |
| Appendix | 533.85 | |
| AtrioventricularNode | 188.65 | |
| BDCA4+_DentriticCells | 9534.75 | |
| Bonemarrow | 692.1 | |
| BronchialEpithelialCells | 61.2 | |
| CD105+_Endothelial | 679.4 | |
| CD14+_Monocytes | 10127.5 | |
| CD19+_BCells(neg._sel.) | 7798.75 | |
| CD33+_Myeloid | 9641.3 | |
| CD34+ | 1974.3 | |
| CD4+_Tcells | 651.35 | |
| CD56+_NKCells | 3425.85 | |
| CD71+_EarlyErythroid | 133.45 | |
| CD8+_Tcells | 509.45 | |
| CardiacMyocytes | 74.05 | |
| Caudatenucleus | 135.25 | |
| Cerebellum | 71.7 | |
| CerebellumPeduncles | 94.4 | |
| CiliaryGanglion | 377.9 | |
| CingulateCortex | 62.4 | |
| Colorectaladenocarcinoma | 48.8 | |
| DorsalRootGanglion | 760 | |
| FetalThyroid | 118 | |
| Fetalbrain | 60.7 | |
| Fetalliver | 90.6 | |
| Fetallung | 529.35 | |
| GlobusPallidus | 50.7 | |
| Heart | 3183.4 | |
| Hypothalamus | 463.45 | |
| Kidney | 442.4 | |
| Leukemia_chronicMyelogenousK-562 | 54.75 | |
| Leukemia_promyelocytic-HL-60 | 4554.9 | |
| Leukemialymphoblastic(MOLT-4) | 49.2 | |
| Liver | 1233.05 | |
| Lung | 9559.6 | |
| Lymphnode | 3817.8 | |
| Lymphoma_burkitts(Daudi) | 3033.05 | |
| Lymphoma_burkitts(Raji) | 8797.55 | |
| MedullaOblongata | 62.65 | |
| OccipitalLobe | 73.2 | |
| OlfactoryBulb | 1068.45 | |
| Ovary | 260.7 | |
| Pancreas | 364.55 | |
| PancreaticIslet | 755.85 | |
| ParietalLobe | 63.55 | |
| Pituitary | 577.1 | |
| Placenta | 406.9 | |
| Pons | 137.55 | |
| PrefrontalCortex | 189.9 | |
| Prostate | 655.35 | |
| Salivarygland | 1510.75 | |
| SkeletalMuscle | 98.7 | |
| Skin | 378.05 | |
| SmoothMuscle | 68.05 | |
| Spinalcord | 994 | |
| SubthalamicNucleus | 101.35 | |
| SuperiorCervicalGanglion | 158.25 | |
| TemporalLobe | 124.2 | |
| Testis | 157.5 | |
| TestisGermCell | 233.35 | |
| TestisIntersitial | 116.35 | |
| TestisLeydigCell | 125 | |
| TestisSeminiferousTubule | 107.75 | |
| Thalamus | 152.45 | |
| Thymus | 2852.65 | |
| Thyroid | 697.2 | |
| Tongue | 208.5 | |
| Tonsil | 4516.15 | |
| Trachea | 1294.95 | |
| TrigeminalGanglion | 412.3 | |
| Uterus | 796.15 | |
| UterusCorpus | 409.25 | |
| WholeBlood | 3421.35 | |
| Wholebrain | 138 | |
| colon | 471.15 | |
| pineal_day | 338.86 | |
| pineal_night | 314.04 | |
| retina | 1187.05 | |
| small_intestine | 1978.8 | |
- Probe name: A_23_P31006
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.76 ± 0.46 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.77 ± 0.53 | |
| Basal Part of Pons | 5.54 ± 0.51 | |
| Cerebellar Cortex | 4.62 ± 0.4 | |
| Cerebellar Nuclei | 6.17 ± 0.33 | |
| Claustrum | 4.48 ± 0.98 | |
| Epithalamus | 6.64 ± 0.54 | |
| Frontal Lobe | 4.89 ± 0.68 | |
| Globus Pallidus | 6.67 ± 0.46 | |
| Hypothalamus | 5.28 ± 1.52 | |
| Insula | 5.22 ± 0.61 | |
| Limbic Lobe | 4.8 ± 0.67 | |
| Mesencephalon | 5.04 ± 0.7 | |
| Myelencephalon | 5.05 ± 0.8 | |
| Occipital Lobe | 4.64 ± 0.53 | |
| Parietal Lobe | 4.83 ± 0.63 | |
| Pontine Tegmentum | 4.79 ± 0.55 | |
| Striatum | 5.73 ± 0.63 | |
| Subthalamus | 5.3 ± 0.46 | |
| Temporal Lobe | 4.93 ± 0.67 | |
| Thalamus | 4.87 ± 0.48 | |
| White Matter | 6.45 ± 0.81 | |
Mouse Brain ISH 
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| 2B11_HUMAN_0 | 0 | 0 | 0 | AVTELGRPDAEYWNSQK | PRIDE |
| 2B11_HUMAN_0 | 0 | 0 | 0 | AVTELGRPDAEYWNSQKDLLEQR | PRIDE |
| 2B11_HUMAN_0 | 0 | 0 | 0 | FDSDVGEYR | PRIDE |
| 2B11_HUMAN_0 | 0 | 0 | 0 | HNYGVGESFTVQR | PRIDE |
| PAp00007124 | 23 | 196 | 218 | SGEVYTCQVEHPSVTSPLTVEWR | Peptide Atlas |