Annotation Detail for HLA-DRB1
Basic Information Top
| Gene Symbol: | HLA-DRB1 ( DRB1,DRw10,FLJ75017,FLJ76359,HLA-DR1B,HLA-DRB,HLA-DRB1*,SS1 ) |
|---|---|
| Gene Full Name: | major histocompatibility complex, class II, DR beta 1 |
| Band: | 6p21.32 |
| Quick Links | Entrez ID:3123; OMIM: 142857; Uniprot ID:2B1F_HUMAN; ENSEMBL ID: ENSG00000196126; HGNC ID: 4948 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.696211
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 15 / 564012 | 26 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 137 / 1939121 | 70 |  |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 28 / 564012 | 49 | |
| neonate | 3 / 31097 | 96 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 4 / 55556 | 71 | |
| adult | 628 / 1939121 | 323 |  |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204670_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6953.5 |  |
| Adipocyte | 61 | |
| AdrenalCortex | 278.15 | |
| Adrenalgland | 799.9 | |
| Amygdala | 123.1 | |
| Appendix | 533.85 | |
| AtrioventricularNode | 188.65 | |
| BDCA4+_DentriticCells | 9534.75 | |
| Bonemarrow | 692.1 | |
| BronchialEpithelialCells | 61.2 | |
| CD105+_Endothelial | 679.4 | |
| CD14+_Monocytes | 10127.5 | |
| CD19+_BCells(neg._sel.) | 7798.75 | |
| CD33+_Myeloid | 9641.3 | |
| CD34+ | 1974.3 | |
| CD4+_Tcells | 651.35 | |
| CD56+_NKCells | 3425.85 | |
| CD71+_EarlyErythroid | 133.45 | |
| CD8+_Tcells | 509.45 | |
| CardiacMyocytes | 74.05 | |
| Caudatenucleus | 135.25 | |
| Cerebellum | 71.7 | |
| CerebellumPeduncles | 94.4 | |
| CiliaryGanglion | 377.9 | |
| CingulateCortex | 62.4 | |
| Colorectaladenocarcinoma | 48.8 | |
| DorsalRootGanglion | 760 | |
| FetalThyroid | 118 | |
| Fetalbrain | 60.7 | |
| Fetalliver | 90.6 | |
| Fetallung | 529.35 | |
| GlobusPallidus | 50.7 | |
| Heart | 3183.4 | |
| Hypothalamus | 463.45 | |
| Kidney | 442.4 | |
| Leukemia_chronicMyelogenousK-562 | 54.75 | |
| Leukemia_promyelocytic-HL-60 | 4554.9 | |
| Leukemialymphoblastic(MOLT-4) | 49.2 | |
| Liver | 1233.05 | |
| Lung | 9559.6 | |
| Lymphnode | 3817.8 | |
| Lymphoma_burkitts(Daudi) | 3033.05 | |
| Lymphoma_burkitts(Raji) | 8797.55 | |
| MedullaOblongata | 62.65 | |
| OccipitalLobe | 73.2 | |
| OlfactoryBulb | 1068.45 | |
| Ovary | 260.7 | |
| Pancreas | 364.55 | |
| PancreaticIslet | 755.85 | |
| ParietalLobe | 63.55 | |
| Pituitary | 577.1 | |
| Placenta | 406.9 | |
| Pons | 137.55 | |
| PrefrontalCortex | 189.9 | |
| Prostate | 655.35 | |
| Salivarygland | 1510.75 | |
| SkeletalMuscle | 98.7 | |
| Skin | 378.05 | |
| SmoothMuscle | 68.05 | |
| Spinalcord | 994 | |
| SubthalamicNucleus | 101.35 | |
| SuperiorCervicalGanglion | 158.25 | |
| TemporalLobe | 124.2 | |
| Testis | 157.5 | |
| TestisGermCell | 233.35 | |
| TestisIntersitial | 116.35 | |
| TestisLeydigCell | 125 | |
| TestisSeminiferousTubule | 107.75 | |
| Thalamus | 152.45 | |
| Thymus | 2852.65 | |
| Thyroid | 697.2 | |
| Tongue | 208.5 | |
| Tonsil | 4516.15 | |
| Trachea | 1294.95 | |
| TrigeminalGanglion | 412.3 | |
| Uterus | 796.15 | |
| UterusCorpus | 409.25 | |
| WholeBlood | 3421.35 | |
| Wholebrain | 138 | |
| colon | 471.15 | |
| pineal_day | 338.86 | |
| pineal_night | 314.04 | |
| retina | 1187.05 | |
| small_intestine | 1978.8 | |
- Probe name: A_23_P31006
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.76 ± 0.46 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.77 ± 0.53 | |
| Basal Part of Pons | 5.54 ± 0.51 | |
| Cerebellar Cortex | 4.62 ± 0.4 | |
| Cerebellar Nuclei | 6.17 ± 0.33 | |
| Claustrum | 4.48 ± 0.98 | |
| Epithalamus | 6.64 ± 0.54 | |
| Frontal Lobe | 4.89 ± 0.68 | |
| Globus Pallidus | 6.67 ± 0.46 | |
| Hypothalamus | 5.28 ± 1.52 | |
| Insula | 5.22 ± 0.61 | |
| Limbic Lobe | 4.8 ± 0.67 | |
| Mesencephalon | 5.04 ± 0.7 | |
| Myelencephalon | 5.05 ± 0.8 | |
| Occipital Lobe | 4.64 ± 0.53 | |
| Parietal Lobe | 4.83 ± 0.63 | |
| Pontine Tegmentum | 4.79 ± 0.55 | |
| Striatum | 5.73 ± 0.63 | |
| Subthalamus | 5.3 ± 0.46 | |
| Temporal Lobe | 4.93 ± 0.67 | |
| Thalamus | 4.87 ± 0.48 | |
| White Matter | 6.45 ± 0.81 | |
Mouse Brain ISH 
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| 2B11_HUMAN_0 | 0 | 0 | 0 | AVTELGRPDAEYWNSQK | PRIDE |
| 2B11_HUMAN_0 | 0 | 0 | 0 | AVTELGRPDAEYWNSQKDLLEQR | PRIDE |
| 2B11_HUMAN_0 | 0 | 0 | 0 | FDSDVGEYR | PRIDE |
| 2B11_HUMAN_0 | 0 | 0 | 0 | HNYGVGESFTVQR | PRIDE |
| PAp00007124 | 23 | 196 | 218 | SGEVYTCQVEHPSVTSPLTVEWR | Peptide Atlas |