AutismKB 2.0

Annotation Detail for HLA-G


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Basic Information Top
Gene Symbol:HLA-G ( MHC-G )
Gene Full Name: major histocompatibility complex, class I, G
Band: 6p22.1
Quick LinksEntrez ID:3135; OMIM: 142871; Uniprot ID:HLAG_HUMAN; ENSEMBL ID: ENSG00000204632; HGNC ID: 4964
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult19 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal26 / 33603077
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine8 / 23447234
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta18 / 28082564
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis4 / 33044212
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210514_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts731.35
Adipocyte172.5
AdrenalCortex179.5
Adrenalgland155.85
Amygdala95.6
Appendix235.8
AtrioventricularNode129.85
BDCA4+_DentriticCells821.65
Bonemarrow394.25
BronchialEpithelialCells172.8
CD105+_Endothelial146.35
CD14+_Monocytes656.35
CD19+_BCells(neg._sel.)565.75
CD33+_Myeloid875.65
CD34+315.7
CD4+_Tcells987.4
CD56+_NKCells1172.2
CD71+_EarlyErythroid165.25
CD8+_Tcells987.3
CardiacMyocytes186.65
Caudatenucleus124.75
Cerebellum91.4
CerebellumPeduncles191.25
CiliaryGanglion120.3
CingulateCortex114.45
Colorectaladenocarcinoma165.75
DorsalRootGanglion131.35
FetalThyroid173.2
Fetalbrain111.7
Fetalliver56.65
Fetallung295.75
GlobusPallidus106.55
Heart310.8
Hypothalamus150.1
Kidney140.75
Leukemia_chronicMyelogenousK-562101.25
Leukemia_promyelocytic-HL-60229.4
Leukemialymphoblastic(MOLT-4)140.45
Liver230.35
Lung1021.6
Lymphnode557
Lymphoma_burkitts(Daudi)302.75
Lymphoma_burkitts(Raji)543.6
MedullaOblongata106.45
OccipitalLobe107.5
OlfactoryBulb199.7
Ovary117.35
Pancreas147.05
PancreaticIslet428.75
ParietalLobe124.9
Pituitary234.8
Placenta525.75
Pons106.4
PrefrontalCortex115.4
Prostate237.15
Salivarygland146
SkeletalMuscle81.8
Skin132.8
SmoothMuscle223.75
Spinalcord171.55
SubthalamicNucleus156.6
SuperiorCervicalGanglion149.7
TemporalLobe102.55
Testis114.3
TestisGermCell143.45
TestisIntersitial123.35
TestisLeydigCell154
TestisSeminiferousTubule145.35
Thalamus114
Thymus277.85
Thyroid286.2
Tongue137.1
Tonsil588.05
Trachea198.15
TrigeminalGanglion144.25
Uterus171.8
UterusCorpus157.1
WholeBlood794.65
Wholebrain104
colon627.7
pineal_day226.48
pineal_night301.36
retina216.825
small_intestine434.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P230288
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.24 ± 1.05
Basal Forebrain2.75 ± 0.44
Basal Part of Pons2.85 ± 0.44
Cerebellar Cortex3.04 ± 0.61
Cerebellar Nuclei3.18 ± 0.69
Claustrum3.27 ± 0.52
Epithalamus2.91 ± 0.74
Frontal Lobe2.78 ± 0.71
Globus Pallidus3 ± 1.17
Hypothalamus2.86 ± 0.81
Insula2.81 ± 0.72
Limbic Lobe2.93 ± 0.59
Mesencephalon3.03 ± 0.99
Myelencephalon2.93 ± 0.63
Occipital Lobe2.9 ± 0.9
Parietal Lobe2.96 ± 0.7
Pontine Tegmentum2.84 ± 0.49
Striatum3.02 ± 0.66
Subthalamus2.96 ± 0.65
Temporal Lobe2.87 ± 0.71
Thalamus2.86 ± 0.69
White Matter3.36 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
H2-M3CBCerebellum2.54
3.84
H2-M3CTXCerebral cortex2.73
2.08
H2-M3HIPHippocampal region1.49
1.46
H2-M3HPFHippocampal formation1.68
1.51
H2-M3HYHypothalamus1.11
1.2
H2-M3LSXLateral septal complex0.11
0.16
H2-M3MBMidbrain1.54
1.9
H2-M3MYMedulla3.69
4.25
H2-M3OLFOlfactory bulb5.71
4.71
H2-M3PPons4.19
5.69
H2-M3PALPallidum0.69
0.6
H2-M3RHPRetrohippocampal region2.2
1.53
H2-M3sAMYStriatum-like amygdalar nuclei0.49
0.47
H2-M3STRStriatum0.7
0.71
H2-M3STRdStriatum dorsal region0.43
0.48
H2-M3STRvStriatum ventral region2.04
1.83
H2-M3THThalamus1.17
1
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00146839 13 268 280 WAAVVVPSGEEQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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