AutismKB 2.0

Annotation Detail for MR1


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Basic Information Top
Gene Symbol:MR1 ( FLJ31593,HLALS )
Gene Full Name: major histocompatibility complex, class I-related
Band: 1q25.3
Quick LinksEntrez ID:3140; OMIM: 600764; Uniprot ID:HMR1_HUMAN; ENSEMBL ID: ENSG00000153029; HGNC ID: 4975
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus2 / 5640123
neonate2 / 3109764
infant1 / 2362042
juvenile0 / 555560 
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma5 / 10688346
head and neck tumor7 / 13630251
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal57 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood9 / 12347872
bone3 / 7165541
bone marrow0 / 488010 
brain16 / 110098914
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine3 / 23447212
kidney8 / 21177737
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph1 / 4427022
lymph node1 / 9161010
mammary gland4 / 15327126
mouth6 / 6705289
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland2 / 16585120
placenta9 / 28082532
prostate4 / 18934521
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach1 / 9661910
testis11 / 33044233
thymus2 / 8113124
thyroid1 / 4747321
tonsil1 / 1699958
trachea4 / 5241376
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210223_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts58
Adipocyte56.8
AdrenalCortex62.5
Adrenalgland52.9
Amygdala51.65
Appendix66.9
AtrioventricularNode47.6
BDCA4+_DentriticCells38
Bonemarrow70.6
BronchialEpithelialCells78.15
CD105+_Endothelial28.05
CD14+_Monocytes53.1
CD19+_BCells(neg._sel.)32.7
CD33+_Myeloid64.4
CD34+45.9
CD4+_Tcells49.55
CD56+_NKCells65.7
CD71+_EarlyErythroid27.15
CD8+_Tcells42.95
CardiacMyocytes73.55
Caudatenucleus46
Cerebellum46.05
CerebellumPeduncles60.85
CiliaryGanglion43
CingulateCortex56.1
Colorectaladenocarcinoma51.5
DorsalRootGanglion42.75
FetalThyroid32.8
Fetalbrain48.45
Fetalliver50.8
Fetallung41.6
GlobusPallidus39.9
Heart148.7
Hypothalamus50.7
Kidney63.4
Leukemia_chronicMyelogenousK-56266.35
Leukemia_promyelocytic-HL-6046.65
Leukemialymphoblastic(MOLT-4)37.05
Liver80.9
Lung60.1
Lymphnode61.6
Lymphoma_burkitts(Daudi)89.65
Lymphoma_burkitts(Raji)81.9
MedullaOblongata45.9
OccipitalLobe37.95
OlfactoryBulb36.1
Ovary42.2
Pancreas40.6
PancreaticIslet63.85
ParietalLobe78.55
Pituitary93.05
Placenta42.35
Pons50.4
PrefrontalCortex51.5
Prostate79.9
Salivarygland38.7
SkeletalMuscle99.25
Skin54.2
SmoothMuscle57.3
Spinalcord54.4
SubthalamicNucleus38.75
SuperiorCervicalGanglion90.45
TemporalLobe45.6
Testis43.55
TestisGermCell39.25
TestisIntersitial44.4
TestisLeydigCell60.9
TestisSeminiferousTubule41.95
Thalamus45.15
Thymus58.1
Thyroid64.65
Tongue56.4
Tonsil57
Trachea56.95
TrigeminalGanglion63
Uterus48.3
UterusCorpus64.15
WholeBlood60.85
Wholebrain38.25
colon42.15
pineal_day58.76
pineal_night54.62
retina61.65
small_intestine42.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P74928
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.9 ± 0.58
Basal Forebrain4.03 ± 0.78
Basal Part of Pons3.57 ± 0.76
Cerebellar Cortex3.29 ± 0.54
Cerebellar Nuclei3.44 ± 0.56
Claustrum3.82 ± 0.55
Epithalamus4.1 ± 0.49
Frontal Lobe3.68 ± 0.58
Globus Pallidus4.5 ± 0.34
Hypothalamus3.55 ± 0.7
Insula3.69 ± 0.65
Limbic Lobe3.87 ± 0.61
Mesencephalon3.72 ± 0.64
Myelencephalon3.73 ± 0.62
Occipital Lobe3.55 ± 0.58
Parietal Lobe3.56 ± 0.64
Pontine Tegmentum3.69 ± 0.59
Striatum4.27 ± 0.39
Subthalamus3.95 ± 0.46
Temporal Lobe3.7 ± 0.59
Thalamus3.49 ± 0.65
White Matter3.15 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mr1CBCerebellum1.01
1.48
Mr1CTXCerebral cortex0.67
0.57
Mr1HIPHippocampal region1.06
1.06
Mr1HPFHippocampal formation1.02
0.97
Mr1HYHypothalamus0.32
0.23
Mr1LSXLateral septal complex0.04
0
Mr1MBMidbrain0.77
1.18
Mr1MYMedulla3.49
4.62
Mr1OLFOlfactory bulb0.61
0.44
Mr1PPons0.53
0.55
Mr1PALPallidum0.64
0.69
Mr1RHPRetrohippocampal region0.93
0.81
Mr1sAMYStriatum-like amygdalar nuclei2.13
2.91
Mr1STRStriatum1.1
1.03
Mr1STRdStriatum dorsal region0.88
0.64
Mr1STRvStriatum ventral region1.4
1.5
Mr1THThalamus0.61
0.55
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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