AutismKB 2.0

Annotation Detail for AOX1


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Basic Information Top
Gene Symbol:AOX1 ( AO,AOH1 )
Gene Full Name: aldehyde oxidase 1
Band: 2q33.1
Quick LinksEntrez ID:316; OMIM: 602841; Uniprot ID:ADO_HUMAN; ENSEMBL ID: ENSG00000138356; HGNC ID: 553
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult63 / 193912132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma14 / 82823169
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal121 / 336030736
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland12 / 33197361
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone6 / 7165583
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart2 / 8962622
intestine3 / 23447212
kidney16 / 21177775
larynx0 / 241450 
liver44 / 207743211
lung4 / 33697411
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate10 / 18934552
salivary gland0 / 201550 
skin5 / 21057423
spleen2 / 5395237
stomach1 / 9661910
testis12 / 33044236
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus4 / 23287817
vascular2 / 5178038
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205083_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.65
Adipocyte366.25
AdrenalCortex548.75
Adrenalgland347.4
Amygdala3.9
Appendix4
AtrioventricularNode3.2
BDCA4+_DentriticCells4.1
Bonemarrow3.65
BronchialEpithelialCells4.25
CD105+_Endothelial3.75
CD14+_Monocytes4
CD19+_BCells(neg._sel.)3.95
CD33+_Myeloid4.8
CD34+4.7
CD4+_Tcells4.05
CD56+_NKCells4.45
CD71+_EarlyErythroid3.4
CD8+_Tcells3.6
CardiacMyocytes4.75
Caudatenucleus3.3
Cerebellum3
CerebellumPeduncles4.15
CiliaryGanglion2.8
CingulateCortex3.75
Colorectaladenocarcinoma3.7
DorsalRootGanglion2.85
FetalThyroid3.6
Fetalbrain3.7
Fetalliver3.2
Fetallung3.1
GlobusPallidus2.75
Heart4.85
Hypothalamus4.05
Kidney87.7
Leukemia_chronicMyelogenousK-5623.35
Leukemia_promyelocytic-HL-603.2
Leukemialymphoblastic(MOLT-4)2.9
Liver39.65
Lung4.15
Lymphnode3.25
Lymphoma_burkitts(Daudi)4.7
Lymphoma_burkitts(Raji)5.15
MedullaOblongata4.65
OccipitalLobe3.35
OlfactoryBulb2.95
Ovary7.85
Pancreas18.5
PancreaticIslet104.05
ParietalLobe3.85
Pituitary4.35
Placenta3.8
Pons3.5
PrefrontalCortex4.45
Prostate7
Salivarygland7.05
SkeletalMuscle5.1
Skin3
SmoothMuscle4.4
Spinalcord3.95
SubthalamicNucleus3.4
SuperiorCervicalGanglion15.65
TemporalLobe3.35
Testis3.9
TestisGermCell10.1
TestisIntersitial3.15
TestisLeydigCell3.8
TestisSeminiferousTubule5.4
Thalamus3.8
Thymus2.9
Thyroid12.05
Tongue3.65
Tonsil3.6
Trachea3.2
TrigeminalGanglion6.05
Uterus3.1
UterusCorpus3.3
WholeBlood3.8
Wholebrain3.05
colon3.75
pineal_day5.82
pineal_night7.02
retina8.35
small_intestine3.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P154037
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.94 ± 0.83
Basal Forebrain2.09 ± 0.43
Basal Part of Pons3.76 ± 0.7
Cerebellar Cortex3.25 ± 0.59
Cerebellar Nuclei2.69 ± 0.87
Claustrum3.04 ± 0.97
Epithalamus2.35 ± 1
Frontal Lobe2.44 ± 0.83
Globus Pallidus2.61 ± 0.89
Hypothalamus2.3 ± 0.55
Insula2.28 ± 0.62
Limbic Lobe3.01 ± 1.01
Mesencephalon2.54 ± 0.73
Myelencephalon2.59 ± 0.89
Occipital Lobe2.56 ± 0.63
Parietal Lobe2.49 ± 0.83
Pontine Tegmentum2.24 ± 0.58
Striatum2.07 ± 0.69
Subthalamus2.7 ± 0.79
Temporal Lobe2.43 ± 0.83
Thalamus2.3 ± 0.77
White Matter2.34 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Aox1CBCerebellum4.47
6.42
Aox1CTXCerebral cortex3.14
2.49
Aox1HIPHippocampal region2.46
2.33
Aox1HPFHippocampal formation3.07
2.8
Aox1HYHypothalamus3.26
5.87
Aox1LSXLateral septal complex1.32
1.43
Aox1MBMidbrain2.73
4.19
Aox1MYMedulla6.32
9.31
Aox1OLFOlfactory bulb5.87
5.8
Aox1PPons3.97
5.38
Aox1PALPallidum1.18
1.72
Aox1RHPRetrohippocampal region4.88
3.98
Aox1sAMYStriatum-like amygdalar nuclei1.82
1.85
Aox1STRStriatum1.67
1.53
Aox1STRdStriatum dorsal region1.18
1
Aox1STRvStriatum ventral region2.59
2.05
Aox1THThalamus2.27
2.42
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010371 22 363 384 HPDSDLNPILAVGNCTLNLLSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018