AutismKB 2.0

Annotation Detail for HMOX2


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Basic Information Top
Gene Symbol:HMOX2 ( HO-2 )
Gene Full Name: heme oxygenase (decycling) 2
Band: 16p13.3
Quick LinksEntrez ID:3163; OMIM: 141251; Uniprot ID:HMOX2_HUMAN; ENSEMBL ID: ENSG00000103415; HGNC ID: 5014
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult98 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor9 / 11936975
germ cell tumor9 / 26384534
glioma9 / 10688384
head and neck tumor2 / 13630214
kidney tumor10 / 68959145
leukemia4 / 9584241
liver tumor8 / 9635983
lung tumor10 / 10312796
lymphoma11 / 71755153
non-neoplasia6 / 9725061
normal150 / 336030744
ovarian tumor10 / 76682130
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer7 / 10268068
retinoblastoma7 / 46356151
skin tumor21 / 124949168
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood5 / 12347840
bone3 / 7165541
bone marrow2 / 4880140
brain78 / 110098970
cervix1 / 4817120
connective tissue7 / 14925546
ear1 / 1621261
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye19 / 21105490
heart4 / 8962644
intestine17 / 23447272
kidney20 / 21177794
larynx0 / 241450 
liver14 / 20774367
lung17 / 33697450
lymph10 / 44270225
lymph node2 / 9161021
mammary gland10 / 15327165
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary13 / 102051127
pancreas10 / 21481246
parathyroid4 / 20539194
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta7 / 28082524
prostate15 / 18934579
salivary gland1 / 2015549
skin22 / 210574104
spleen3 / 5395255
stomach4 / 9661941
testis33 / 33044299
thymus2 / 8113124
thyroid0 / 474730 
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218120_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts125.95
Adipocyte46
AdrenalCortex30.9
Adrenalgland39.45
Amygdala82.35
Appendix28.7
AtrioventricularNode22.8
BDCA4+_DentriticCells45.9
Bonemarrow30.3
BronchialEpithelialCells206.4
CD105+_Endothelial24.5
CD14+_Monocytes37.25
CD19+_BCells(neg._sel.)41.15
CD33+_Myeloid25.15
CD34+29.05
CD4+_Tcells226.15
CD56+_NKCells214.75
CD71+_EarlyErythroid20.4
CD8+_Tcells186.15
CardiacMyocytes61.45
Caudatenucleus56.75
Cerebellum38.45
CerebellumPeduncles72.65
CiliaryGanglion18.55
CingulateCortex73.45
Colorectaladenocarcinoma61.35
DorsalRootGanglion22.7
FetalThyroid32
Fetalbrain41.5
Fetalliver17.2
Fetallung31.65
GlobusPallidus35.75
Heart144
Hypothalamus101.65
Kidney39.5
Leukemia_chronicMyelogenousK-56233.35
Leukemia_promyelocytic-HL-6049.25
Leukemialymphoblastic(MOLT-4)28.1
Liver133.45
Lung119.55
Lymphnode32.85
Lymphoma_burkitts(Daudi)41.65
Lymphoma_burkitts(Raji)62.9
MedullaOblongata82.25
OccipitalLobe102.25
OlfactoryBulb25.9
Ovary20.05
Pancreas40.3
PancreaticIslet41.5
ParietalLobe94.05
Pituitary49.75
Placenta36.65
Pons56.05
PrefrontalCortex96.45
Prostate48.65
Salivarygland26.4
SkeletalMuscle56.85
Skin22.7
SmoothMuscle96.65
Spinalcord49.05
SubthalamicNucleus38.85
SuperiorCervicalGanglion34.25
TemporalLobe57.75
Testis198.45
TestisGermCell109.1
TestisIntersitial282.9
TestisLeydigCell100.05
TestisSeminiferousTubule129.2
Thalamus114.4
Thymus42.15
Thyroid38.6
Tongue32.1
Tonsil37.55
Trachea27.55
TrigeminalGanglion29.85
Uterus24.7
UterusCorpus31.95
WholeBlood112.85
Wholebrain220.7
colon36.1
pineal_day48.9
pineal_night55.96
retina61.575
small_intestine36.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P100501
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.53 ± 0.51
Basal Forebrain9.78 ± 0.46
Basal Part of Pons10.64 ± 0.2
Cerebellar Cortex9.68 ± 0.16
Cerebellar Nuclei10.74 ± 0.21
Claustrum9.84 ± 0.49
Epithalamus9.66 ± 0.29
Frontal Lobe10.28 ± 0.34
Globus Pallidus9.55 ± 0.47
Hypothalamus10.04 ± 0.16
Insula10.11 ± 0.25
Limbic Lobe9.84 ± 0.6
Mesencephalon9.83 ± 0.44
Myelencephalon9.94 ± 0.53
Occipital Lobe9.33 ± 0.6
Parietal Lobe10.03 ± 0.47
Pontine Tegmentum9.95 ± 0.32
Striatum9.71 ± 0.58
Subthalamus10.61 ± 0.36
Temporal Lobe10.13 ± 0.41
Thalamus9.94 ± 0.3
White Matter10.15 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hmox2CBCerebellum41.12
74.22
Hmox2CTXCerebral cortex87.09
90.12
Hmox2HIPHippocampal region93.09
100
Hmox2HPFHippocampal formation96.1
100
Hmox2HYHypothalamus81.62
67.55
Hmox2LSXLateral septal complex53.73
38.84
Hmox2MBMidbrain66.99
60.75
Hmox2MYMedulla71.33
88.2
Hmox2OLFOlfactory bulb77.2
82.42
Hmox2PPons73.88
85.82
Hmox2PALPallidum75.45
74.42
Hmox2RHPRetrohippocampal region100
100
Hmox2sAMYStriatum-like amygdalar nuclei80.97
70.94
Hmox2STRStriatum66.53
51.76
Hmox2STRdStriatum dorsal region62.95
46.19
Hmox2STRvStriatum ventral region76.01
63.58
Hmox2THThalamus78.09
85.52
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
HMOX2_HUMAN_2 28 2 29 SAEVETSEGVDESEKKNSGALEKENQMR PRIDE
HMOX2_HUMAN_226 21 226 246 AFEYNMQIFNELDQAGSTLAR PRIDE
HMOX2_HUMAN_90 16 90 105 DHPAFAPLYFPMELHR PRIDE
PAp00001624 16 90 105 DHPAFAPLYFPMELHR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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