AutismKB 2.0

Annotation Detail for DDX51


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Basic Information Top
Gene Symbol:DDX51 ( DKFZp686N2081,MGC42193 )
Gene Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
Band: 12q24.33
Quick LinksEntrez ID:317781; OMIM: NA; Uniprot ID:DDX51_HUMAN; ENSEMBL ID: ENSG00000185163; HGNC ID: 20082
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult83 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor5 / 26384518
glioma7 / 10688365
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma10 / 71755139
non-neoplasia0 / 972500 
normal112 / 336030733
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites3 / 4001574
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain17 / 110098915
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye52 / 211054246
heart1 / 8962611
intestine2 / 2344728
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung11 / 33697432
lymph8 / 44270180
lymph node0 / 916100 
mammary gland8 / 15327152
mouth3 / 6705244
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta4 / 28082514
prostate5 / 18934526
salivary gland0 / 201550 
skin6 / 21057428
spleen1 / 5395218
stomach0 / 966190 
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214968_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.7
Adipocyte3.35
AdrenalCortex3.5
Adrenalgland2.85
Amygdala3.55
Appendix3.4
AtrioventricularNode2.55
BDCA4+_DentriticCells7.3
Bonemarrow3.3
BronchialEpithelialCells3.35
CD105+_Endothelial3.85
CD14+_Monocytes3.65
CD19+_BCells(neg._sel.)4.2
CD33+_Myeloid6
CD34+5.05
CD4+_Tcells3.85
CD56+_NKCells4.5
CD71+_EarlyErythroid3.15
CD8+_Tcells3.7
CardiacMyocytes4.3
Caudatenucleus3.2
Cerebellum2.7
CerebellumPeduncles3.8
CiliaryGanglion2.35
CingulateCortex3.45
Colorectaladenocarcinoma3.4
DorsalRootGanglion2.6
FetalThyroid3.3
Fetalbrain3.35
Fetalliver2.9
Fetallung2.8
GlobusPallidus2.6
Heart4.3
Hypothalamus3.7
Kidney2.75
Leukemia_chronicMyelogenousK-5623.05
Leukemia_promyelocytic-HL-603
Leukemialymphoblastic(MOLT-4)2.7
Liver4.65
Lung3.7
Lymphnode2.95
Lymphoma_burkitts(Daudi)4.3
Lymphoma_burkitts(Raji)5.35
MedullaOblongata3.1
OccipitalLobe3.05
OlfactoryBulb2.65
Ovary2.25
Pancreas2.7
PancreaticIslet3.6
ParietalLobe3.55
Pituitary3.9
Placenta3.5
Pons3.3
PrefrontalCortex4.25
Prostate3.9
Salivarygland2.7
SkeletalMuscle4
Skin2.55
SmoothMuscle3.8
Spinalcord3.55
SubthalamicNucleus3.1
SuperiorCervicalGanglion4.25
TemporalLobe3.1
Testis2.9
TestisGermCell2.8
TestisIntersitial2.8
TestisLeydigCell3.4
TestisSeminiferousTubule2.9
Thalamus3.45
Thymus2.7
Thyroid4.25
Tongue3.7
Tonsil3.3
Trachea2.8
TrigeminalGanglion3.3
Uterus2.8
UterusCorpus3.1
WholeBlood3.65
Wholebrain2.85
colon3.4
pineal_day4.26
pineal_night4.12
retina4.1
small_intestine3.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6270_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.86 ± 0.59
Basal Forebrain4.89 ± 0.52
Basal Part of Pons5.45 ± 0.45
Cerebellar Cortex5.31 ± 0.57
Cerebellar Nuclei4.9 ± 0.55
Claustrum4.57 ± 0.86
Epithalamus5.28 ± 0.69
Frontal Lobe5.38 ± 0.56
Globus Pallidus4.56 ± 0.44
Hypothalamus5.35 ± 0.57
Insula5.44 ± 0.33
Limbic Lobe5.16 ± 0.59
Mesencephalon5.14 ± 0.57
Myelencephalon5.15 ± 0.64
Occipital Lobe4.85 ± 0.58
Parietal Lobe5.2 ± 0.57
Pontine Tegmentum5.12 ± 0.62
Striatum4.73 ± 0.63
Subthalamus5.23 ± 0.77
Temporal Lobe5.41 ± 0.55
Thalamus5.16 ± 0.48
White Matter5.04 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ddx51CBCerebellum3.01
4.05
Ddx51CTXCerebral cortex1.25
1.06
Ddx51HIPHippocampal region2.99
3.02
Ddx51HPFHippocampal formation4.83
4.29
Ddx51HYHypothalamus0.26
0.31
Ddx51LSXLateral septal complex0
0
Ddx51MBMidbrain0.77
0.74
Ddx51MYMedulla3.13
3.14
Ddx51OLFOlfactory bulb3.22
3.64
Ddx51PPons2.23
2.2
Ddx51PALPallidum0.11
0.2
Ddx51RHPRetrohippocampal region8.33
6.36
Ddx51sAMYStriatum-like amygdalar nuclei0
0
Ddx51STRStriatum0.34
0.3
Ddx51STRdStriatum dorsal region0.47
0.43
Ddx51STRvStriatum ventral region0.22
0.2
Ddx51THThalamus0.64
0.77
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00074290 17 350 366 LVDHIDQTPGFSLQQLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018