AutismKB 2.0

Annotation Detail for HNRNPK


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HNRNPK ( CSBP,FLJ41122,HNRPK,TUNP )
Gene Full Name: heterogeneous nuclear ribonucleoprotein K
Band: 9q21.32
Quick LinksEntrez ID:3190; OMIM: 600712; Uniprot ID:HNRPK_HUMAN; ENSEMBL ID: ENSG00000165119; HGNC ID: 5044
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body36 / 70761508
blastocyst36 / 62319577
fetus270 / 564012478
neonate37 / 310971189
infant30 / 236201270
juvenile68 / 555561223
adult753 / 1939121388
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor8 / 12794625
bladder carcinoma14 / 17475801
breast (mammary gland) tumor88 / 94178934
cervical tumor15 / 34366436
chondrosarcoma28 / 82823338
colorectal tumor37 / 114246323
esophageal tumor19 / 172901098
gastrointestinal tumor51 / 119369427
germ cell tumor243 / 263845920
glioma37 / 106883346
head and neck tumor84 / 136302616
kidney tumor38 / 68959551
leukemia49 / 95842511
liver tumor46 / 96359477
lung tumor25 / 103127242
lymphoma35 / 71755487
non-neoplasia34 / 97250349
normal1446 / 3360307430
ovarian tumor28 / 76682365
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS101 / 125680803
prostate cancer36 / 102680350
retinoblastoma36 / 46356776
skin tumor62 / 124949496
soft tissue/muscle tissue tumor45 / 125191359
uterine tumor51 / 90257565
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland21 / 33197632
ascites14 / 40015349
bladder27 / 29757907
blood89 / 123478720
bone17 / 71655237
bone marrow26 / 48801532
brain668 / 1100989606
cervix16 / 48171332
connective tissue46 / 149255308
ear3 / 16212185
embryonic tissue132 / 215722611
esophagus23 / 202091138
eye82 / 211054388
heart39 / 89626435
intestine78 / 234472332
kidney106 / 211777500
larynx29 / 241451201
liver67 / 207743322
lung91 / 336974270
lymph11 / 44270248
lymph node21 / 91610229
mammary gland120 / 153271782
mouth44 / 67052656
muscle30 / 107715278
nerve9 / 15768570
ovary31 / 102051303
pancreas32 / 214812148
parathyroid7 / 20539340
pharynx52 / 413281258
pituitary gland3 / 16585180
placenta82 / 280825291
prostate57 / 189345301
salivary gland4 / 20155198
skin105 / 210574498
spleen32 / 53952593
stomach36 / 96619372
testis187 / 330442565
thymus120 / 811311479
thyroid17 / 47473358
tonsil1 / 1699958
trachea23 / 52413438
umbilical cord4 / 13680292
uterus127 / 232878545
vascular24 / 51780463
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200097_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1904.2
Adipocyte519.65
AdrenalCortex380.15
Adrenalgland356.75
Amygdala958.15
Appendix304.55
AtrioventricularNode114.65
BDCA4+_DentriticCells1663.7
Bonemarrow390.3
BronchialEpithelialCells922.25
CD105+_Endothelial1489.75
CD14+_Monocytes1270.6
CD19+_BCells(neg._sel.)1712.6
CD33+_Myeloid2125.35
CD34+1959.3
CD4+_Tcells1516.1
CD56+_NKCells1938.3
CD71+_EarlyErythroid1369.65
CD8+_Tcells1674.55
CardiacMyocytes520.95
Caudatenucleus364.7
Cerebellum325.7
CerebellumPeduncles522.05
CiliaryGanglion154.75
CingulateCortex452.25
Colorectaladenocarcinoma695.65
DorsalRootGanglion186.1
FetalThyroid611.3
Fetalbrain785.5
Fetalliver418.1
Fetallung592.4
GlobusPallidus284.55
Heart79.35
Hypothalamus932.8
Kidney240.1
Leukemia_chronicMyelogenousK-562350.4
Leukemia_promyelocytic-HL-60615.2
Leukemialymphoblastic(MOLT-4)471.35
Liver126.7
Lung375.6
Lymphnode488.5
Lymphoma_burkitts(Daudi)783
Lymphoma_burkitts(Raji)639.75
MedullaOblongata393.25
OccipitalLobe574.45
OlfactoryBulb491.2
Ovary293.95
Pancreas369.05
PancreaticIslet699.95
ParietalLobe401.9
Pituitary878.7
Placenta848.05
Pons269
PrefrontalCortex736.05
Prostate737.5
Salivarygland494.25
SkeletalMuscle74.1
Skin288.95
SmoothMuscle951.8
Spinalcord499.95
SubthalamicNucleus264.2
SuperiorCervicalGanglion107
TemporalLobe329.15
Testis378.9
TestisGermCell627.1
TestisIntersitial294.05
TestisLeydigCell301.65
TestisSeminiferousTubule292.95
Thalamus411.65
Thymus790.35
Thyroid1296.45
Tongue223.95
Tonsil620.25
Trachea570.7
TrigeminalGanglion114.9
Uterus590.4
UterusCorpus268.2
WholeBlood859.45
Wholebrain470.25
colon1443.1
pineal_day1338.62
pineal_night1376.18
retina1365.575
small_intestine1472.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P389517
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.7 ± 0.2
Basal Forebrain9.53 ± 0.15
Basal Part of Pons9.6 ± 0.28
Cerebellar Cortex9.67 ± 0.29
Cerebellar Nuclei9.6 ± 0.25
Claustrum9.62 ± 0.48
Epithalamus9.73 ± 0.21
Frontal Lobe9.56 ± 0.24
Globus Pallidus9.69 ± 0.24
Hypothalamus9.65 ± 0.34
Insula9.66 ± 0.22
Limbic Lobe9.76 ± 0.28
Mesencephalon9.66 ± 0.26
Myelencephalon9.63 ± 0.25
Occipital Lobe9.92 ± 0.33
Parietal Lobe9.58 ± 0.24
Pontine Tegmentum9.65 ± 0.25
Striatum9.74 ± 0.27
Subthalamus9.48 ± 0.14
Temporal Lobe9.57 ± 0.24
Thalamus9.64 ± 0.22
White Matter10.29 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
HnrpkCBCerebellum24.16
42.2
HnrpkCTXCerebral cortex81.34
77.43
HnrpkHIPHippocampal region79.04
100
HnrpkHPFHippocampal formation87.01
100
HnrpkHYHypothalamus20.63
19.43
HnrpkLSXLateral septal complex30.9
28.85
HnrpkMBMidbrain28.65
30.36
HnrpkMYMedulla17.5
23.54
HnrpkOLFOlfactory bulb63.13
68.18
HnrpkPPons23.06
29.61
HnrpkPALPallidum23.48
25.54
HnrpkRHPRetrohippocampal region97.16
100
HnrpksAMYStriatum-like amygdalar nuclei60.19
52.85
HnrpkSTRStriatum39.82
35.92
HnrpkSTRdStriatum dorsal region40.97
37.21
HnrpkSTRvStriatum ventral region31.6
27.96
HnrpkTHThalamus38.48
39.2
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
HNRPK_HUMAN_0 0 0 0 IILDLISESPIK PRIDE
HNRPK_HUMAN_0 0 0 0 IITITGTQDQIQNAQYLLQNSVK PRIDE
HNRPK_HUMAN_0 0 0 0 ILSISADIETIGEILKK PRIDE
HNRPK_HUMAN_0 0 0 0 TDYNASVSVPDSSGPER PRIDE
HNRPK_HUMAN_1 22 1 22 METEQPEETFPNTETNGEFGKR PRIDE
HNRPK_HUMAN_139 9 139 147 GSDFDCELR PRIDE
HNRPK_HUMAN_148 15 148 162 LLIHQSLAGGIIGVK PRIDE
HNRPK_HUMAN_179 12 179 190 LFQECCPHSTDR PRIDE
HNRPK_HUMAN_192 10 192 201 VVLIGGKPDR PRIDE
HNRPK_HUMAN_207 12 207 218 IILDLISESPIK PRIDE
HNRPK_HUMAN_207 14 207 220 IILDLISESPIKGR PRIDE
HNRPK_HUMAN_208 12 208 219 IILDLISESPIK PRIDE
HNRPK_HUMAN_21 14 21 34 RPAEDMEEEQAFKR PRIDE
HNRPK_HUMAN_22 13 22 34 RPAEDMEEEQAFK PRIDE
HNRPK_HUMAN_278 9 278 286 RDYDDMSPR PRIDE
HNRPK_HUMAN_279 8 279 286 DYDDMSPR PRIDE
HNRPK_HUMAN_305 11 305 315 NLPLPPPPPPR PRIDE
HNRPK_HUMAN_307 10 307 316 LPLPPPPPPR PRIDE
HNRPK_HUMAN_317 9 317 325 GGDLMAYDR PRIDE
HNRPK_HUMAN_35 11 35 45 SRNTDEMVELR PRIDE
HNRPK_HUMAN_377 19 377 395 GSYGDLGGPIITTQVTIPK PRIDE
HNRPK_HUMAN_38 9 38 46 NTDEMVELR PRIDE
HNRPK_HUMAN_39 8 39 46 TDEMVELR PRIDE
HNRPK_HUMAN_414 19 414 432 HESGASIKIDEPLEGSEDR PRIDE
HNRPK_HUMAN_422 11 422 432 IDEPLEGSEDR PRIDE
HNRPK_HUMAN_423 11 423 433 IDEPLEGSEDR PRIDE
HNRPK_HUMAN_433 23 433 455 IITITGTQDQIQNAQYLLQNSVK PRIDE
HNRPK_HUMAN_434 23 434 456 IITITGTQDQIQNAQYLLQNSVK PRIDE
HNRPK_HUMAN_66 20 66 85 ALRTDYNASVSVPDSSGPER PRIDE
HNRPK_HUMAN_69 17 69 85 TDYNASVSVPDSSGPER PRIDE
HNRPK_HUMAN_70 17 70 86 TDYNASVSVPDSSGPER PRIDE
HNRPK_HUMAN_86 16 86 101 ILSISADIETIGEILK PRIDE
HNRPK_HUMAN_86 17 86 102 ILSISADIETIGEILKK PRIDE
PAp00003099 9 140 148 GSDFDCELR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved