AutismKB 2.0

Annotation Detail for HNRNPU


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Basic Information Top
Gene Symbol:HNRNPU ( HNRPU,SAF-A,U21.1,hnRNP U )
Gene Full Name: heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
Band: 1q44
Quick LinksEntrez ID:3192; OMIM: 602869; Uniprot ID:HNRPU_HUMAN; ENSEMBL ID: ENSG00000153187; HGNC ID: 5048
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body42 / 70761593
blastocyst35 / 62319561
fetus163 / 564012289
neonate12 / 31097385
infant8 / 23620338
juvenile18 / 55556323
adult604 / 1939121311
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma10 / 17475572
breast (mammary gland) tumor23 / 94178244
cervical tumor15 / 34366436
chondrosarcoma26 / 82823313
colorectal tumor47 / 114246411
esophageal tumor4 / 17290231
gastrointestinal tumor30 / 119369251
germ cell tumor162 / 263845613
glioma28 / 106883261
head and neck tumor53 / 136302388
kidney tumor15 / 68959217
leukemia47 / 95842490
liver tumor23 / 96359238
lung tumor22 / 103127213
lymphoma38 / 71755529
non-neoplasia19 / 97250195
normal949 / 3360307282
ovarian tumor13 / 76682169
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS39 / 125680310
prostate cancer24 / 102680233
retinoblastoma10 / 46356215
skin tumor44 / 124949352
soft tissue/muscle tissue tumor36 / 125191287
uterine tumor18 / 90257199
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland4 / 33197120
ascites17 / 40015424
bladder17 / 29757571
blood61 / 123478494
bone27 / 71655376
bone marrow18 / 48801368
brain325 / 1100989295
cervix18 / 48171373
connective tissue37 / 149255247
ear2 / 16212123
embryonic tissue111 / 215722514
esophagus4 / 20209197
eye49 / 211054232
heart18 / 89626200
intestine64 / 234472272
kidney56 / 211777264
larynx4 / 24145165
liver50 / 207743240
lung132 / 336974391
lymph36 / 44270813
lymph node9 / 9161098
mammary gland40 / 153271260
mouth36 / 67052536
muscle20 / 107715185
nerve8 / 15768507
ovary17 / 102051166
pancreas25 / 214812116
parathyroid4 / 20539194
pharynx4 / 4132896
pituitary gland5 / 16585301
placenta66 / 280825235
prostate34 / 189345179
salivary gland3 / 20155148
skin82 / 210574389
spleen14 / 53952259
stomach10 / 96619103
testis158 / 330442478
thymus40 / 81131493
thyroid16 / 47473337
tonsil1 / 1699958
trachea22 / 52413419
umbilical cord2 / 13680146
uterus58 / 232878249
vascular13 / 51780251
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216855_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts21.15
Adipocyte5.1
AdrenalCortex5.45
Adrenalgland4.35
Amygdala5
Appendix5.15
AtrioventricularNode4.05
BDCA4+_DentriticCells7.5
Bonemarrow5.1
BronchialEpithelialCells5
CD105+_Endothelial5.4
CD14+_Monocytes5.45
CD19+_BCells(neg._sel.)5.55
CD33+_Myeloid8.1
CD34+6.6
CD4+_Tcells5.7
CD56+_NKCells6.2
CD71+_EarlyErythroid6.15
CD8+_Tcells5.05
CardiacMyocytes6.85
Caudatenucleus4.6
Cerebellum4.15
CerebellumPeduncles6.1
CiliaryGanglion3.7
CingulateCortex6.1
Colorectaladenocarcinoma5.1
DorsalRootGanglion4.05
FetalThyroid5
Fetalbrain5.2
Fetalliver4.4
Fetallung3.95
GlobusPallidus3.75
Heart6.7
Hypothalamus5.5
Kidney4.2
Leukemia_chronicMyelogenousK-5624.6
Leukemia_promyelocytic-HL-604.45
Leukemialymphoblastic(MOLT-4)4.3
Liver6.7
Lung5.35
Lymphnode4.35
Lymphoma_burkitts(Daudi)6.5
Lymphoma_burkitts(Raji)7.2
MedullaOblongata4.75
OccipitalLobe4.6
OlfactoryBulb3.95
Ovary3.4
Pancreas4.15
PancreaticIslet5.45
ParietalLobe5.45
Pituitary6.1
Placenta4.95
Pons4.85
PrefrontalCortex6.25
Prostate5.9
Salivarygland4.05
SkeletalMuscle6.25
Skin4
SmoothMuscle5.8
Spinalcord5.45
SubthalamicNucleus4.65
SuperiorCervicalGanglion6.1
TemporalLobe4.6
Testis4.35
TestisGermCell4.35
TestisIntersitial4.3
TestisLeydigCell5.05
TestisSeminiferousTubule4.65
Thalamus5.2
Thymus4.05
Thyroid6.05
Tongue5.1
Tonsil5
Trachea4.3
TrigeminalGanglion5.3
Uterus3.95
UterusCorpus4.55
WholeBlood5.35
Wholebrain4.15
colon5.05
pineal_day6.26
pineal_night6.04
retina6.05
small_intestine4.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P51894
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.68 ± 0.49
Basal Forebrain7.75 ± 0.23
Basal Part of Pons7.43 ± 0.26
Cerebellar Cortex8.12 ± 0.22
Cerebellar Nuclei7.7 ± 0.25
Claustrum7.26 ± 0.34
Epithalamus8.04 ± 0.37
Frontal Lobe7.64 ± 0.33
Globus Pallidus7.48 ± 0.27
Hypothalamus7.72 ± 0.25
Insula7.66 ± 0.22
Limbic Lobe7.72 ± 0.35
Mesencephalon7.74 ± 0.32
Myelencephalon7.68 ± 0.36
Occipital Lobe8.02 ± 0.29
Parietal Lobe7.7 ± 0.32
Pontine Tegmentum7.68 ± 0.32
Striatum7.81 ± 0.41
Subthalamus7.77 ± 0.11
Temporal Lobe7.65 ± 0.29
Thalamus7.57 ± 0.27
White Matter8.05 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
HnrpuCBCerebellum100
100
HnrpuCTXCerebral cortex100
100
HnrpuHIPHippocampal region100
100
HnrpuHPFHippocampal formation100
100
HnrpuHYHypothalamus100
100
HnrpuLSXLateral septal complex100
100
HnrpuMBMidbrain100
100
HnrpuMYMedulla100
100
HnrpuOLFOlfactory bulb100
100
HnrpuPPons100
100
HnrpuPALPallidum100
100
HnrpuRHPRetrohippocampal region100
100
HnrpusAMYStriatum-like amygdalar nuclei100
100
HnrpuSTRStriatum100
100
HnrpuSTRdStriatum dorsal region100
100
HnrpuSTRvStriatum ventral region100
100
HnrpuTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
HNRPU_HUMAN_0 0 0 0 DIDIHEVR PRIDE
HNRPU_HUMAN_0 0 0 0 DLPEHAVLK PRIDE
HNRPU_HUMAN_0 0 0 0 EKPYFPIPEEYTFIQNVPLEDR PRIDE
HNRPU_HUMAN_0 0 0 0 NFILDQTNVSAAAQR PRIDE
HNRPU_HUMAN_0 0 0 0 SSGPTSLFAVTVAPPGAR PRIDE
HNRPU_HUMAN_1 22 1 22 SSSPVNVKKLKVSELKEELKKR PRIDE
HNRPU_HUMAN_186 18 186 203 SSGPTSLFAVTVAPPGAR PRIDE
HNRPU_HUMAN_2 22 2 23 SSSPVNVKKLKVSELKEELKKR PRIDE
HNRPU_HUMAN_232 12 232 243 GKTEQKGGDKKR PRIDE
HNRPU_HUMAN_254 13 254 266 GYFEYIEENKYSR PRIDE
HNRPU_HUMAN_330 8 330 337 GKVCFEMK PRIDE
HNRPU_HUMAN_351 8 351 358 DIDIHEVR PRIDE
HNRPU_HUMAN_435 26 435 460 EVLAGRPLFPHVLCHNCAVEFNFGQK PRIDE
HNRPU_HUMAN_461 22 461 482 EKPYFPIPEEYTFIQNVPLEDR PRIDE
HNRPU_HUMAN_494 15 494 508 DCEVVMMIGLPGAGK PRIDE
HNRPU_HUMAN_515 20 515 534 HAAENPGKYNILGTNTIMDK PRIDE
HNRPU_HUMAN_523 12 523 534 YNILGTNTIMDK PRIDE
HNRPU_HUMAN_523 20 523 542 YNILGTNTIMDKMMVAGFKK PRIDE
HNRPU_HUMAN_543 14 543 556 QMADTGKLNTLLQR PRIDE
HNRPU_HUMAN_564 7 564 570 FIEIAAR PRIDE
HNRPU_HUMAN_573 16 573 588 RNFILDQTNVSAAAQR PRIDE
HNRPU_HUMAN_574 15 574 588 NFILDQTNVSAAAQR PRIDE
HNRPU_HUMAN_574 16 574 589 NFILDQTNVSAAAQRR PRIDE
HNRPU_HUMAN_591 9 591 599 MCLFAGFQR PRIDE
HNRPU_HUMAN_625 9 625 633 DLPEHAVLK PRIDE
PAp00000803 12 603 614 AVVVCPKDEDYK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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