Annotation Detail for ACACB
Basic Information Top
| Gene Symbol: | ACACB ( ACC2,ACCB,HACC275 ) |
|---|---|
| Gene Full Name: | acetyl-CoA carboxylase beta |
| Band: | 12q24.11 |
| Quick Links | Entrez ID:32; OMIM: 601557; Uniprot ID:ACACB_HUMAN; ENSEMBL ID: ENSG00000076555; HGNC ID: 85 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.234898
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 16 / 564012 | 28 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 89 / 1939121 | 45 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 |  |
| breast (mammary gland) tumor | 27 / 94178 | 286 |  |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 6 / 263845 | 22 | |
| glioma | 1 / 106883 | 9 |  |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 100 / 3360307 | 29 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 4 / 90257 | 44 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 14 / 13106 | 1068 |  |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 0 / 123478 | 0 | |
| bone | 4 / 71655 | 55 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 20 / 1100989 | 18 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 5 / 211054 | 23 | |
| heart | 3 / 89626 | 33 | |
| intestine | 7 / 234472 | 29 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 2 / 24145 | 82 | |
| liver | 2 / 207743 | 9 | |
| lung | 2 / 336974 | 5 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 37 / 153271 | 241 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 3 / 15768 | 190 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 8 / 214812 | 37 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 3 / 210574 | 14 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 1 / 96619 | 10 | |
| testis | 36 / 330442 | 108 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 4 / 47473 | 84 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 221928_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6.05 | |
| Adipocyte | 573.45 | |
| AdrenalCortex | 26.25 | |
| Adrenalgland | 8.4 | |
| Amygdala | 5.9 | |
| Appendix | 6.85 | |
| AtrioventricularNode | 5.5 | |
| BDCA4+_DentriticCells | 6 | |
| Bonemarrow | 5.65 | |
| BronchialEpithelialCells | 4.95 | |
| CD105+_Endothelial | 5.3 | |
| CD14+_Monocytes | 5.95 | |
| CD19+_BCells(neg._sel.) | 5.2 | |
| CD33+_Myeloid | 6.95 | |
| CD34+ | 7.5 | |
| CD4+_Tcells | 6.5 | |
| CD56+_NKCells | 5.75 | |
| CD71+_EarlyErythroid | 5 | |
| CD8+_Tcells | 6.45 | |
| CardiacMyocytes | 6.05 | |
| Caudatenucleus | 5.7 | |
| Cerebellum | 5.05 | |
| CerebellumPeduncles | 6.55 | |
| CiliaryGanglion | 5.95 | |
| CingulateCortex | 8.25 | |
| Colorectaladenocarcinoma | 4.9 | |
| DorsalRootGanglion | 4.6 | |
| FetalThyroid | 27.1 | |
| Fetalbrain | 6.15 | |
| Fetalliver | 5.85 | |
| Fetallung | 4.8 | |
| GlobusPallidus | 4.15 | |
| Heart | 6.85 | |
| Hypothalamus | 8.1 | |
| Kidney | 9.25 | |
| Leukemia_chronicMyelogenousK-562 | 4.35 | |
| Leukemia_promyelocytic-HL-60 | 5.5 | |
| Leukemialymphoblastic(MOLT-4) | 4.75 | |
| Liver | 31.55 | |
| Lung | 8.45 | |
| Lymphnode | 5.1 | |
| Lymphoma_burkitts(Daudi) | 6.9 | |
| Lymphoma_burkitts(Raji) | 8 | |
| MedullaOblongata | 5.85 | |
| OccipitalLobe | 4.8 | |
| OlfactoryBulb | 7.15 | |
| Ovary | 3.95 | |
| Pancreas | 4.55 | |
| PancreaticIslet | 9.65 | |
| ParietalLobe | 6.1 | |
| Pituitary | 16.45 | |
| Placenta | 5.75 | |
| Pons | 6.65 | |
| PrefrontalCortex | 8.4 | |
| Prostate | 6.4 | |
| Salivarygland | 4.45 | |
| SkeletalMuscle | 12.95 | |
| Skin | 4.65 | |
| SmoothMuscle | 3.9 | |
| Spinalcord | 6.6 | |
| SubthalamicNucleus | 5.4 | |
| SuperiorCervicalGanglion | 7.8 | |
| TemporalLobe | 5.35 | |
| Testis | 4.8 | |
| TestisGermCell | 4.7 | |
| TestisIntersitial | 4.75 | |
| TestisLeydigCell | 5.65 | |
| TestisSeminiferousTubule | 5 | |
| Thalamus | 6.35 | |
| Thymus | 6.95 | |
| Thyroid | 19.35 | |
| Tongue | 12.15 | |
| Tonsil | 5.6 | |
| Trachea | 6.1 | |
| TrigeminalGanglion | 7.45 | |
| Uterus | 6.3 | |
| UterusCorpus | 5.1 | |
| WholeBlood | 6.05 | |
| Wholebrain | 4.3 | |
| colon | 11.85 | |
| pineal_day | 14.38 | |
| pineal_night | 8.28 | |
| retina | 12.35 | |
| small_intestine | 7.6 | |
- Probe name: A_23_P87791
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.26 ± 0.9 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.6 ± 0.5 | |
| Basal Part of Pons | 2.82 ± 0.47 | |
| Cerebellar Cortex | 3.14 ± 0.72 | |
| Cerebellar Nuclei | 3.18 ± 0.83 | |
| Claustrum | 3.07 ± 0.62 | |
| Epithalamus | 3.88 ± 0.77 | |
| Frontal Lobe | 3.12 ± 0.68 | |
| Globus Pallidus | 4.49 ± 0.42 | |
| Hypothalamus | 2.81 ± 0.4 | |
| Insula | 2.79 ± 0.53 | |
| Limbic Lobe | 3.08 ± 0.66 | |
| Mesencephalon | 3.39 ± 0.67 | |
| Myelencephalon | 3.26 ± 0.67 | |
| Occipital Lobe | 3.51 ± 0.59 | |
| Parietal Lobe | 3.16 ± 0.61 | |
| Pontine Tegmentum | 3.35 ± 0.7 | |
| Striatum | 3.4 ± 0.75 | |
| Subthalamus | 3.24 ± 0.45 | |
| Temporal Lobe | 3.13 ± 0.61 | |
| Thalamus | 3.63 ± 0.55 | |
| White Matter | 4.13 ± 0.47 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Acacb | CB | Cerebellum | 1.04 | |
| 1.2 | | |||
| Acacb | CTX | Cerebral cortex | 1.14 | |
| 1.12 | | |||
| Acacb | HIP | Hippocampal region | 1.11 | |
| 1.01 | | |||
| Acacb | HPF | Hippocampal formation | 0.86 | |
| 0.71 | | |||
| Acacb | HY | Hypothalamus | 0.51 | |
| 0.33 | | |||
| Acacb | LSX | Lateral septal complex | 0.25 | |
| 0.21 | | |||
| Acacb | MB | Midbrain | 0.5 | |
| 0.49 | | |||
| Acacb | MY | Medulla | 2.56 | |
| 3.05 | | |||
| Acacb | OLF | Olfactory bulb | 2.11 | |
| 2.23 | | |||
| Acacb | P | Pons | 1.12 | |
| 1.35 | | |||
| Acacb | PAL | Pallidum | 1.23 | |
| 0.99 | | |||
| Acacb | RHP | Retrohippocampal region | 0.43 | |
| 0.31 | | |||
| Acacb | sAMY | Striatum-like amygdalar nuclei | 0.43 | |
| 0.3 | | |||
| Acacb | STR | Striatum | 0.56 | |
| 0.44 | | |||
| Acacb | STRd | Striatum dorsal region | 0.27 | |
| 0.21 | | |||
| Acacb | STRv | Striatum ventral region | 1.46 | |
| 0.95 | | |||
| Acacb | TH | Thalamus | 0.83 | |
| 0.77 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00006676 | 19 | 341 | 359 | RIPVQAVWAGWGHASENPK | Peptide Atlas |