AutismKB 2.0

Annotation Detail for HPCA


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Basic Information Top
Gene Symbol:HPCA ( BDR2 )
Gene Full Name: hippocalcin
Band: 1p35.1
Quick LinksEntrez ID:3208; OMIM: 142622; Uniprot ID:HPCA_HUMAN; ENSEMBL ID: ENSG00000121905; HGNC ID: 5144
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult23 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma5 / 10688346
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal78 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma6 / 46356129
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain70 / 110098963
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye17 / 21105480
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205454_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.9
Adipocyte8.85
AdrenalCortex18.95
Adrenalgland6.5
Amygdala468.2
Appendix8.15
AtrioventricularNode8.75
BDCA4+_DentriticCells7.3
Bonemarrow7.9
BronchialEpithelialCells7.9
CD105+_Endothelial7.05
CD14+_Monocytes7.7
CD19+_BCells(neg._sel.)7.4
CD33+_Myeloid9.1
CD34+8.85
CD4+_Tcells7.3
CD56+_NKCells8.05
CD71+_EarlyErythroid6.85
CD8+_Tcells6.45
CardiacMyocytes10.25
Caudatenucleus3924.8
Cerebellum10.75
CerebellumPeduncles36.8
CiliaryGanglion6.6
CingulateCortex489.85
Colorectaladenocarcinoma7.4
DorsalRootGanglion6.8
FetalThyroid7.15
Fetalbrain276.3
Fetalliver6.65
Fetallung5.7
GlobusPallidus130.25
Heart11.5
Hypothalamus18
Kidney7.15
Leukemia_chronicMyelogenousK-5627.65
Leukemia_promyelocytic-HL-606.5
Leukemialymphoblastic(MOLT-4)6
Liver11.5
Lung7.95
Lymphnode7.1
Lymphoma_burkitts(Daudi)12.9
Lymphoma_burkitts(Raji)11.2
MedullaOblongata1381
OccipitalLobe326.1
OlfactoryBulb6.35
Ovary8.1
Pancreas6.05
PancreaticIslet7.95
ParietalLobe220.85
Pituitary10
Placenta7.1
Pons721.95
PrefrontalCortex825.2
Prostate8.15
Salivarygland9
SkeletalMuscle17.35
Skin17.15
SmoothMuscle9.8
Spinalcord9.4
SubthalamicNucleus236.1
SuperiorCervicalGanglion10.95
TemporalLobe449.4
Testis7.7
TestisGermCell6.1
TestisIntersitial13.15
TestisLeydigCell7.25
TestisSeminiferousTubule7.6
Thalamus128.15
Thymus6.05
Thyroid8.45
Tongue13.7
Tonsil7.95
Trachea6.6
TrigeminalGanglion13.65
Uterus8.1
UterusCorpus9.8
WholeBlood7.6
Wholebrain606.9
colon7.45
pineal_day11.94
pineal_night10.54
retina9.125
small_intestine7.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P126159
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.25 ± 0.91
Basal Forebrain5.7 ± 1.28
Basal Part of Pons5.5 ± 0.37
Cerebellar Cortex5.85 ± 0.59
Cerebellar Nuclei4.98 ± 0.79
Claustrum6.36 ± 0.71
Epithalamus5.23 ± 0.53
Frontal Lobe6.4 ± 0.87
Globus Pallidus5.11 ± 1
Hypothalamus5.71 ± 0.9
Insula6.61 ± 0.41
Limbic Lobe7.54 ± 1.17
Mesencephalon5.86 ± 0.8
Myelencephalon6.24 ± 1
Occipital Lobe5.86 ± 0.73
Parietal Lobe6.22 ± 0.61
Pontine Tegmentum6.57 ± 0.99
Striatum9.33 ± 1.04
Subthalamus5.48 ± 0.27
Temporal Lobe6.5 ± 0.47
Thalamus5.53 ± 0.8
White Matter2.45 ± 0.75
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
HpcaCBCerebellum37.13
100
HpcaCTXCerebral cortex100
100
HpcaHIPHippocampal region100
100
HpcaHPFHippocampal formation100
100
HpcaHYHypothalamus100
100
HpcaLSXLateral septal complex100
100
HpcaMBMidbrain100
100
HpcaMYMedulla86.14
98.91
HpcaOLFOlfactory bulb100
100
HpcaPPons83.51
85.71
HpcaPALPallidum93.51
96.92
HpcaRHPRetrohippocampal region100
100
HpcasAMYStriatum-like amygdalar nuclei100
100
HpcaSTRStriatum100
100
HpcaSTRdStriatum dorsal region100
100
HpcaSTRvStriatum ventral region100
100
HpcaTHThalamus66.2
66.86
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064680 14 37 50 DCPTGILNVDEFKK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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